Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Mohammad Shaquiquzzaman"'
Autor:
Garima Verma, Mohemmed Faraz Khan, Wasim Akhtar, Mohammad Mumtaz Alam, Mymoona Akhter, Ozair Alam, Syed Misbahul Hasan, Mohammad Shaquiquzzaman
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4815-4839 (2019)
Pharmacophore modeling, molecular docking and in silico ADME prediction have been performed for quinazoline based EGFR inhibitors. This study has been carried out to determine the binding mode and drug likeliness nature of compounds. A five point mod
Externí odkaz:
https://doaj.org/article/83178623bd9140449a1b276965888699
Autor:
Mohemmed Faraz Khan, Garima Verma, Wasim Akhtar, Mohammad Shaquiquzzaman, Mymoona Akhter, Moshahid Alam Rizvi, Mohammad Mumtaz Alam
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 5000-5018 (2019)
Pharmacophore modeling, molecular docking, and in silico ADME studies have been carried out to determine the binding mode and drug likeliness profile of acyl 1,3,4-thiadiazole amides and sulfonamides as antitubulin agents. A four point pharmacophore
Externí odkaz:
https://doaj.org/article/fa1dd03d3f9946499838fa3c4042bb9f
Autor:
Mohammad Amir, payal kamboj, null Anjali, Asif Husain, Mohammad shaquiquzzaman, M.Mumtaz Alam
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 23
Abstract: Cancer is one of the severe diseases in which abnormal cells divide and proliferate in an uncontrolled manner without any regulation. Globally cancer is among the leading causes of death; according to a recent report of by the WHO, around 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d00b12b5f50f5ab32f69b9e9d38cb5ff
https://doi.org/10.2174/1389557523666230201113237
https://doi.org/10.2174/1389557523666230201113237
Autor:
Mohammad Shaquiquzzaman, Barkha Sharma, Mohammad Ahmed Khan, Mohammad Mumtaz Alam, Mymoona Akhter, Ashif Iqubal, Anish Madan, Garvit Satija, Suhel Parvez
Publikováno v:
Journal of Heterocyclic Chemistry. 59:22-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b6743f9682047872208bae4ca17e02
https://doi.org/10.1002/jhet.4355
https://doi.org/10.1002/jhet.4355
Autor:
Garima Verma, Akranth Marella, Mohammad Shaquiquzzaman, Mymoona Akhtar, Mohammad Rahmat Ali, Mohammad Mumtaz Alam
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 6, Iss 2, Pp 69-80 (2014)
The development of novel compounds, hydrazones has shown that they possess a wide variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti-inflammatory, analgesic, antiplatelet, antimalarial, anticancer, antifungal, a
Externí odkaz:
https://doaj.org/article/1503adeeae164d5cba7c81f15e7fa10e
Autor:
Mymoona Akhter, Nadeem Siddiqui, Abul Kalam Najmi, Asif Husain, Shaista Amin, Mohammad Mumtaz Alam, Mohammad Shaquiquzzaman
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 196:211-274
Phosphorus oxychloride, POCl3, an important phosphorus compound, has diverse applications in synthetic chemistry. It plays an important role in chlorination, Vilsmeier Haack reaction, dehydration a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a2f1c57ecc25d140fd44a0cf89e40a0
https://doi.org/10.1080/10426507.2020.1831499
https://doi.org/10.1080/10426507.2020.1831499
Autor:
Sharba Tasneem, Khursheed A. Sheikh, Md Naematullah, M. Mumtaz Alam, Farah Khan, Manika Garg, Mohd. Amir, Mymoona Akhter, Shaista Amin, Anzarul Haque, Mohammad Shaquiquzzaman
Publikováno v:
Bioorganic chemistry. 126
A series of novel cyanopyrimidine-hydrazone hybrids were synthesized and characterized with various spectroscopic techniques. The synthesized compounds were tested at NCI, USA, on a 60-cell line panel and most of the compounds showed remarkable cytot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594c021c1d6573d4b620a322de7ec113
https://pubmed.ncbi.nlm.nih.gov/35636128
https://pubmed.ncbi.nlm.nih.gov/35636128
Autor:
Garima Verma, Meher Rizvi, Mohemmed Faraz Khan, Wasim Akhtar, Mymoona Akhter, Mohammad Mumtaz Alam, Mohammad Shaquiquzzaman
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 5000-5018 (2019)
Pharmacophore modeling, molecular docking, and in silico ADME studies have been carried out to determine the binding mode and drug likeliness profile of acyl 1,3,4-thiadiazole amides and sulfonamides as antitubulin agents. A four point pharmacophore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333dca9391c2f6f8620e8780ec18aa9
https://doi.org/10.1016/j.arabjc.2016.11.004
https://doi.org/10.1016/j.arabjc.2016.11.004
Autor:
Sharba Tasneem, Mohammad Mumtaz Alam, Mohammad Amir, Mymoona Akhter, Suhel Parvez, Garima Verma, Lalit Mohan Nainwal, Ashif Equbal, Tarique Anwer, Mohammad Shaquiquzzaman
Publikováno v:
Mini reviews in medicinal chemistry. 22(12)
Abstract: ‘Epigenetic’ regulation of genes via post-translational modulation of proteins is a wellexplored approach for disease therapies, particularly cancer chemotherapeutics. Histone deacetylases (HDACs) are one of the important epigenetic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfcd0ece9c92a7fc01aa3e0a8dca1c7
https://pubmed.ncbi.nlm.nih.gov/34939540
https://pubmed.ncbi.nlm.nih.gov/34939540
Autor:
Garima Verma, Mohammad Shaquiquzzaman, Perwez Alam, Mohammad Mumtaz Alam, Afroz Bakht, Mymoona Akhter, Syed Misbahul Hasan, Mohemmed Faraz Khan
Publikováno v:
Computers in Biology and Medicine. 110:175-185
In the present study, a series of dibenzepinones, dibenzoxepines, and benzosuberones targeting p38α MAP kinase were subjected to pharmacophore modelling, 3D-QSAR and molecular docking studies. The IC50 values for these 67 compounds ranged between 0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef134ef58bf1e5557224a641b9d607bb
https://doi.org/10.1016/j.compbiomed.2019.05.023
https://doi.org/10.1016/j.compbiomed.2019.05.023