Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Mohammad Shahjahani"'
Autor:
Mohammad Shahjahani, Elham Homaei Hadad, Shirin Azizidoost, Kowsar Chenani Nezhad, Saeid Shahrabi
Publikováno v:
Oncology Reviews, Vol 13, Iss 1 (2019)
Complex karyotype (CK) is a poor prognosis factor in hematological malignancies. Studies have shown that the presence of CK in myelodysplastic syndrome (MDS) can be associated with MDS progression to acute myeloid leukemia. The goal of this review wa
Externí odkaz:
https://doaj.org/article/d40ab3694fcf4b28bd7cac68d4c5a089
Autor:
Najmaldin Saki, Saeid Abroun, Fatemeh Salari, Fakher Rahim, Mohammad Shahjahani, Javad Mohammadi-Asl
Publikováno v:
Cell Journal, Vol 17, Iss 2, Pp 193-200 (2016)
β-thalassemia is the most common single gene disorder worldwide, in which hemoglobin β-chain production is decreased. Today, the life expectancy of thalassemic patients is increased because of a variety of treatment methods; however treatment rel
Externí odkaz:
https://doaj.org/article/b4e65cda2fdc43ed8d6178d677bef03a
Expression of CD markers in JAK2V617F positive myeloproliferative neoplasms: Prognostic significance
Publikováno v:
Oncology Reviews, Vol 12, Iss 2 (2018)
Myeloproliferative neoplasms (MPNs) are clonal stem cell disorders characterized by the presence of JAK2V617F mutation. Thrombohemorrhagic as well as autoimmune or inflammatory phenomena are common clinical outcomes of these disorders. Recent studies
Externí odkaz:
https://doaj.org/article/25adac0ad0a946aa90fd66c86e16a418
Autor:
Seyed Mohammad Sadegh Pezeshki, Ali Amin Asnafi, Abbas Khosravi, Mohammad Shahjahani, Shirin Azizidoost, Saeid Shahrabi
Publikováno v:
Oncology Reviews, Vol 12, Iss 2 (2018)
Several factors such as chromosomal translocations, gene mutations, and polymorphisms are involved in the pathogenesis of leukemia/lymphoma. Recently, the role of vitamin D (VD) and vitamin D receptor (VDR) polymorphisms in hematologic malignancies h
Externí odkaz:
https://doaj.org/article/a1acaa24fa684050b6c6f4e479d23ac1
Publikováno v:
Cell Journal, Vol 16, Iss 2, Pp 99-110 (2014)
Multiple myeloma (MM), is the second most common blood cancer after non-Hodgkin’s lymphoma. Genetic changes, structural and numerical chromosome anomalies, are involved in pathogenesis of MM, and are among the most important prognostic factors of d
Externí odkaz:
https://doaj.org/article/a1203ccd0e464b66858cd1b4f00c9908
Publikováno v:
Oncology Reviews, Vol 10, Iss 2 (2016)
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic neoplasms ocurring mostly in the elderly. The clinical outcome of MDS patients is still poor despite progress in treatment approaches. About 90% of patients harbor at least one
Externí odkaz:
https://doaj.org/article/988ec0d3fa564b1c86424c2f46b73612
Autor:
Fakher Rahim, Hossein Allahmoradi, Fatemeh Salari, Mohammad Shahjahani, Ali Dehghani Fard, Seyed Ahmad Hosseini, Hadi Mousakhani
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 7, Iss 3, Pp 40-45 (2013)
Potent induction of fetal hemoglobin (HbF) production results in alleviating the complications of β-thalassemia and sickle cell disease (SCD). HbF inducer agents can trigger several molecular signaling pathways critical for erythropoiesis. Janus kin
Externí odkaz:
https://doaj.org/article/deb35d2a03ac4acabb2522b65ab1017e
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 7, Iss 3, Pp 46-53 (2013)
Objective: The use of fetal hemoglobin (HbF) inducer drugs is considered as a novel approach in treatment of β-hemoglobinopathies, especially β- thalassemia and sickle cell disease. HbF inducers including hydroxyurea, histone deacetylase (HDAC) inh
Externí odkaz:
https://doaj.org/article/ee94c8037bf341fe828390eeb22938d8
Autor:
Mehdi Azad, Saeid Kaviani, Mehrdad Noruzinia, Yousef Mortazavi, Naser Mobarra, Shaban Alizadeh, Mohammad Shahjahani, Fatemeh Skandari, Mohammad Hosein Ahmadi, Amir Atashi, Saeid Abroun, Zahra Zonoubi
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 16, Iss 7, Pp 822-828 (2013)
Objective(s): Stem cell differentiation into different cell lineages depends upon several factors, cell cycle control elements and intracellular signaling elements, including P15INK4b and P16INK4a genes. Epigenetics may be regarded as a control mecha
Externí odkaz:
https://doaj.org/article/ce65fabab761436998c50296b4ed829c
Autor:
Ali Dehghanifard, Mohammad Shahjahani, Hamid Galehdari, Fakher Rahim, Fatemeh Hamid, Kaveh Jaseb, Asnafi Ali Amin, Mohammad Ali Jalalifar, Najmaldin Saki
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 7, Iss 2, Pp 17-22 (2013)
Background: Hemoglobinopathy and thalassemia are prevalent genetic disorders throughout the world. Beta thalassemia is one of these disorders with high prevalence in Iran, especially in Khuzestan province. In this study, the rate of different mutatio
Externí odkaz:
https://doaj.org/article/166e03ed48944cb2ab0e1e95373720c8