Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mohammad S. Radi"'
Publikováno v:
Membranes, Vol 14, Iss 3, p 70 (2024)
Transport systems play a pivotal role in bacterial physiology and represent potential targets for medical and biotechnological applications. However, even in well-studied organisms like Escherichia coli, a notable proportion of transporters, exceedin
Externí odkaz:
https://doaj.org/article/d0b2415f16794974bbbab1a2cb2879c4
Autor:
Mohammad S. Radi, Lachlan J. Munro, Jesus E. Salcedo-Sora, Se Hyeuk Kim, Adam M. Feist, Douglas B. Kell
Publikováno v:
Membranes, Vol 12, Iss 12, p 1264 (2022)
Multidrug transporters (MDTs) are major contributors to microbial drug resistance and are further utilized for improving host phenotypes in biotechnological applications. Therefore, the identification of these MDTs and the understanding of their mech
Externí odkaz:
https://doaj.org/article/65a4a4026b0a431f9bd77bfbbfb71455
Autor:
Elsayed T. Mohamed, Allison Z. Werner, Davinia Salvachúa, Christine A. Singer, Kiki Szostkiewicz, Manuel Rafael Jiménez-Díaz, Thomas Eng, Mohammad S. Radi, Blake A. Simmons, Aindrila Mukhopadhyay, Markus J. Herrgård, Steven W. Singer, Gregg T. Beckham, Adam M. Feist
Publikováno v:
Metabolic Engineering Communications, Vol 11, Iss , Pp e00143- (2020)
Pseudomonas putida KT2440 is a promising bacterial chassis for the conversion of lignin-derived aromatic compound mixtures to biofuels and bioproducts. Despite the inherent robustness of this strain, further improvements to aromatic catabolism and to
Externí odkaz:
https://doaj.org/article/095611f6aa0a4faea7a5d658dc52663d
Autor:
Mohammad S. Radi, Jesus E. SalcedoSora, Se Hyeuk Kim, Suresh Sudarsan, Anand V. Sastry, Douglas B. Kell, Markus J. Herrgård, Adam M. Feist
Publikováno v:
Radi, M S, SalcedoSora, J E, Kim, S H, Sudarsan, S, Sastry, A V, Kell, D B, Herrgård, M J & Feist, A M 2022, ' Membrane transporter identification and modulation via adaptive laboratory evolution ', Metabolic Engineering, vol. 72, pp. 376-390 . https://doi.org/10.1016/j.ymben.2022.05.004
Membrane transport proteins are potential targets for medical and biotechnological applications. However, more than 30% of reported membrane transporter families are either poorly characterized or lack adequate functional annotation. Here, adaptive l
Autor:
Jens Nielsen, Elsayed Tharwat Tolba Mohamed, Carl Malina, Yun Chen, Mohammad S. Radi, Adam M. Feist, Markus J. Herrgård, Yongjun Wei, Rui Pedro Gomes Pereira
Publikováno v:
Metabolic Engineering. 56:130-141
Improving the growth phenotypes of microbes in high product concentrations is an essential design objective in the development of robust cell factories. However, the limited knowledge regarding tolerance mechanisms makes rational design of such trait
Autor:
Mohammad S. Radi, Solange I. Mussatto, Elsayed Tharwat Tolba Mohamed, Zhijia Liu, Giuliano Dragone, Adam M. Feist
Publikováno v:
Liu, Z, Radi, M, Mohamed, E T T, Feist, A M, Dragone, G & Mussatto, S I 2021, ' Adaptive laboratory evolution of Rhodosporidium toruloides to inhibitors derived from lignocellulosic biomass and genetic variations behind evolution ', Bioresource Technology, vol. 333, 125171 . https://doi.org/10.1016/j.biortech.2021.125171
Using lignocellulosic biomass hydrolysate for the production of microbial lipids and carotenoids is still a challenge due to the poor tolerance of oleaginous yeasts to the inhibitors generated during biomass pretreatment. In this study, a strategy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e9f64d73317f51d8524d88255d885b
https://orbit.dtu.dk/en/publications/09e78785-91f7-4a13-a0f5-f29da2ae18bc
https://orbit.dtu.dk/en/publications/09e78785-91f7-4a13-a0f5-f29da2ae18bc
Autor:
Adam M. Feist, Allison Z. Werner, Blake A. Simmons, Aindrila Mukhopadhyay, Christine A. Singer, Elsayed Tharwat Tolba Mohamed, Steven W. Singer, Manuel Rafael Jiménez-Díaz, Davinia Salvachúa, Gregg T. Beckham, Kiki Szostkiewicz, Mohammad S. Radi, Markus J. Herrgård, Thomas Eng
Publikováno v:
Metabolic Engineering Communications, Vol 11, Iss, Pp e00143-(2020)
Metabolic Engineering Communications
Mohamed, E T T, Werner, A Z, Salvachúa, D, Singer, C A, Szostkiewicz, K, Rafael Jiménez-Díaz, M, Eng, T, Radi, M S, Simmons, B A, Mukhopadhyay, A, Herrgård, M J, Singer, S W, Beckham, G T & Feist, A M 2020, ' Adaptive laboratory evolution of Pseudomonas putida KT2440 improves p-coumaric and ferulic acid catabolism and tolerance ', Metabolic Engineering Communications, vol. 11, e00143 . https://doi.org/10.1016/j.mec.2020.e00143
Metabolic Engineering Communications
Mohamed, E T T, Werner, A Z, Salvachúa, D, Singer, C A, Szostkiewicz, K, Rafael Jiménez-Díaz, M, Eng, T, Radi, M S, Simmons, B A, Mukhopadhyay, A, Herrgård, M J, Singer, S W, Beckham, G T & Feist, A M 2020, ' Adaptive laboratory evolution of Pseudomonas putida KT2440 improves p-coumaric and ferulic acid catabolism and tolerance ', Metabolic Engineering Communications, vol. 11, e00143 . https://doi.org/10.1016/j.mec.2020.e00143
Pseudomonas putida KT2440 is a promising bacterial chassis for the conversion of lignin-derived aromatic compound mixtures to biofuels and bioproducts. Despite the inherent robustness of this strain, further improvements to aromatic catabolism and to
Autor:
Rui, Pereira, Elsayed T, Mohamed, Mohammad S, Radi, Markus J, Herrgård, Adam M, Feist, Jens, Nielsen, Yun, Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Understanding the tolerance mechanism to inhibiting chemicals can help in the design of more robust microbial strains for use in industrial bioprocesses. Aromatic acids are important bioactive molecules and precursors for many plant natu
Autor:
Rui Pedro Gomes Pereira, Adam M. Feist, Markus J. Herrgård, Mohammad S. Radi, Elsayed Tharwat Tolba Mohamed, Jens Nielsen, Yun Chen
Publikováno v:
Pereira, R, Mohamed, E T T, Radi, M S, Herrgård, M J, Feist, A M, Nielsen, J & Chen, Y 2020, ' Elucidating aromatic acid tolerance at low pH in Saccharomyces cerevisiae using adaptive laboratory evolution ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 45, pp. 27954-27961 . https://doi.org/10.1073/pnas.2013044117
Toxicity from the external presence or internal production of compounds can reduce the growth and viability of microbial cell factories and compromise productivity. Aromatic compounds are generally toxic for microorganisms, which makes their producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f5575e8380cb7b3bce2eeba1357ca4
https://orbit.dtu.dk/en/publications/f66a0cf1-8088-44b0-a6c7-74b4735e00c9
https://orbit.dtu.dk/en/publications/f66a0cf1-8088-44b0-a6c7-74b4735e00c9