Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mohammad S. Alavijeh"'
Autor:
Mohammad S. Alavijeh, Alan M. Palmer
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 1, Pp 38-47 (2010)
The need to discover and develop safe and effective new medicines is greatest for disorders of the CNS. A core requirement for an effective neurotherapeutic agent is an ability to cross the blood–brain barrier and remain in the brain interstitial f
Externí odkaz:
https://doaj.org/article/f9e5df1ec98846589117233ae5004e72
Autor:
Aaron Tan, Debbie Goh, Yasmin Farhatnia, Natasha G, Jing Lim, Swee-Hin Teoh, Jayakumar Rajadas, Mohammad S Alavijeh, Alexander M Seifalian
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77112 (2013)
In situ endothelialization of cardiovascular implants has emerged in recent years as an attractive means of targeting the persistent problems of thrombosis and intimal hyperplasia. This study aimed to investigate the efficacy of immobilizing anti-CD3
Externí odkaz:
https://doaj.org/article/06223a95f9ee42b297850079221bd57c
Autor:
Krisztina László, Gergely Stankovits, Anil Misra, Mohammad S. Alavijeh, András Szilágyi, Benjámin Gyarmati, Zoltán Varga, Dóra Barczikai, Aysel Mammadova
Publikováno v:
Polymer Degradation and Stability. 188:109577
We describe the controlled degradation of cysteamine-modified polyaspartamides bearing N,N-dimethyl-2-aminoethyl (DME), N,N-dimethyl-3-aminopropyl (DMP) or 2-hydroxyethyl (HE) side groups. The hydrolytic stability of polyaspartamides was studied at p
Publikováno v:
Archiv der Pharmazie. 352(3)
Four series of novel compounds based on 4-aminopyridine, glatiramer acetate, pyrone, and coumarin backbones were sufficiently synthesized and identified by spectroscopic methods. CYP enzyme inhibition assays of five predominate human P450 isozymes in
Autor:
Reza Zadmard, Nahid S. Alavijeh, Saeed Balalaie, Sorour Ramezanpour, Frank Rominger, Mohammad S. Alavijeh
Publikováno v:
New Journal of Chemistry. 39:6578-6584
In this study, we developed an efficient synthesis of α-hydrazino tetrazolocalix[4]arene derivatives in good yields under mild conditions via an Ugi-azide multicomponent reaction. Metal ion binding properties of one of the α-hydrazino tetrazolocali
Autor:
Anil Misra, Sorour Ramezanpour, Saeed Balalaie, Frank Rominger, Hamid Reza Bijanzadeh, Nahid S. Alavijeh, Mohammad S. Alavijeh
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 145:349-356
An efficient synthesis of indole-containing pseudopeptides via an Ugi four-component reaction among indolecarboxylic acids, aromatic aldehydes, primary amines, and isocyanides in methanol is described. The lipophilicity of the synthesized compounds w
Autor:
Alexander M. Seifalian, Aaron Tan, Jayakumar Rajadas, Mohammad S. Alavijeh, Yasmin Farhatnia, Debbie Goh
Publikováno v:
Molecular Pharmaceutics. 10:1279-1298
Cardiovascular disease is one of the major causes of death in the world. Coronary stenting in percutaneous coronary intervention (PCI) has revolutionized the field of cardiology. Coronary stenting is seen as a less invasive procedure compared to coro
Publikováno v:
Organic letters. 18(19)
Water-soluble peptidocalix[4]arenes were synthesized by the introduction of arginine-rich narrow groove-binding residues at lower rims through solid-phase synthesis. The study of binding of these water-soluble bidentate ligands to well-matched and mi
Autor:
Alan M. Palmer, Mohammad S. Alavijeh
Publikováno v:
Drug Discovery Today. 17:1068-1078
The major imperative of the pharmaceutical industry is to effectively translate insights gained from basic research into new medicines. This task is toughest for CNS disorders. Compared with non-CNS drugs, CNS drugs take longer to get to market and t
Autor:
Alan M. Palmer, David R. Howlett, Jill C. Richardson, Mohammad S. Alavijeh, Elizabeth S. Ash, Martin Broadstock, Paul T. Francis, Cathy Mitchelmore
Publikováno v:
Neurochemistry International. 57:504-511
Oxidative stress is implicated in the pathogenesis of Alzheimer's disease (AD) causing neurodegeneration and decreased monoamine neurotransmitters. We investigated the effect of administration of a pro-oxidant diet on the levels of monoamines and met