Zobrazeno 1 - 10
of 308
pro vyhledávání: '"Mohammad R K Mofrad"'
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0244430 (2021)
Understanding the functionality of proteins has emerged as a critical problem in recent years due to significant roles of these macro-molecules in biological mechanisms. However, in-laboratory techniques for protein function prediction are not as eff
Externí odkaz:
https://doaj.org/article/3d20d88b0a2a4db696fb9eec5b972696
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract The gut microbiome plays a major role in human health; however, little is known about the structural arrangement of microbes and factors governing their distribution. In this work, we present an in silico agent-based model (ABM) to conceptua
Externí odkaz:
https://doaj.org/article/1426d470ec2141a6ae40abba8bf83214
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179601 (2017)
Bacterial adhesion to collagen, the most abundant protein in humans, is a critical step in the initiation and persistence of numerous bacterial infections. In this study, we explore the collagen binding mechanism of the multi-modular cell wall anchor
Externí odkaz:
https://doaj.org/article/d09a2885e6fb490ab7f3be78b9b3df9e
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Deep learning has demonstrated significant advancements across various domains. However, its implementation in specialized areas, such as medical settings, remains approached with caution. In these high-stake environments, underst
Externí odkaz:
https://doaj.org/article/d70101377721430091fe589808137498
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143745 (2015)
Nucleocytoplasmic transport has been the subject of a large body of research in the past few decades. Recently, the focus of investigations in this field has shifted from studies of the overall function of the nuclear pore complex (NPC) to the examin
Externí odkaz:
https://doaj.org/article/5aed37c5d6f748dc8543f8efab2414ba
Autor:
Ehsaneddin Asgari, Mohammad R K Mofrad
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141287 (2015)
We introduce a new representation and feature extraction method for biological sequences. Named bio-vectors (BioVec) to refer to biological sequences in general with protein-vectors (ProtVec) for proteins (amino-acid sequences) and gene-vectors (Gene
Externí odkaz:
https://doaj.org/article/156bb7072a664ffd9c89158608d7a03f
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0112969 (2015)
Molecular traffic between the nucleus and the cytoplasm is regulated by the nuclear pore complex (NPC), which acts as a highly selective channel perforating the nuclear envelope in eukaryotic cells. The human immunodeficiency virus (HIV) exploits the
Externí odkaz:
https://doaj.org/article/e708b34cab5844a9806147bf6c217ed4
Publikováno v:
Nucleus, Vol 15, Iss 1 (2024)
The nuclear pore complex (NPC) is a critical gateway regulating molecular transport between the nucleus and cytoplasm. It allows small molecules to pass freely, while larger molecules require nuclear transport receptors to traverse the barrier. This
Externí odkaz:
https://doaj.org/article/4e9fb2de625d4b60930a0fb866d9b359
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93709 (2014)
While much has been devoted to the study of transport mechanisms through the nuclear pore complex (NPC), the specifics of interactions and binding between export transport receptors and the NPC periphery have remained elusive. Recent work has demonst
Externí odkaz:
https://doaj.org/article/dcca44e1138a48b6af954d67ca6d8f7c
Autor:
Javad Golji, Mohammad R K Mofrad
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 4, p e1002995 (2013)
Vinculin can interact with F-actin both in recruitment of actin filaments to the growing focal adhesions and also in capping of actin filaments to regulate actin dynamics. Using molecular dynamics, both interactions are simulated using different vinc
Externí odkaz:
https://doaj.org/article/b7bdcfb925ee4e20b4af0812c92d142a