Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mohammad R Ahmadian"'
Autor:
Franziska Altmüller, Santosh Pothula, Anil Annamneedi, Saeideh Nakhaei-Rad, Carolina Montenegro-Venegas, Eneko Pina-Fernández, Claudia Marini, Monica Santos, Denny Schanze, Dirk Montag, Mohammad R Ahmadian, Oliver Stork, Martin Zenker, Anna Fejtova
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006843 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006684.].
Externí odkaz:
https://doaj.org/article/9f508d33e6cd48faa1a9521ab6557376
Autor:
Franziska Altmüller, Santosh Pothula, Anil Annamneedi, Saeideh Nakhaei-Rad, Carolina Montenegro-Venegas, Eneko Pina-Fernández, Claudia Marini, Monica Santos, Denny Schanze, Dirk Montag, Mohammad R Ahmadian, Oliver Stork, Martin Zenker, Anna Fejtova
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006684 (2017)
Noonan syndrome (NS) is characterized by reduced growth, craniofacial abnormalities, congenital heart defects, and variable cognitive deficits. NS belongs to the RASopathies, genetic conditions linked to mutations in components and regulators of the
Externí odkaz:
https://doaj.org/article/4d79c075e1a8490e85b7c3fa7893b496
Autor:
Kazem Nouri, Jens M Moll, Lech-Gustav Milroy, Anika Hain, Radovan Dvorsky, Ehsan Amin, Michael Lenders, Luitgard Nagel-Steger, Sebastian Howe, Sander H J Smits, Hartmut Hengel, Lutz Schmitt, Carsten Münk, Luc Brunsveld, Mohammad R Ahmadian
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143634 (2015)
Nucleophosmin (NPM1, also known as B23, numatrin or NO38) is a pentameric RNA-binding protein with RNA and protein chaperon functions. NPM1 has increasingly emerged as a potential cellular factor that directly associates with viral proteins; however,
Externí odkaz:
https://doaj.org/article/67bcfb11095e42e4b4a741f5615c7956
Autor:
Mohamed S Taha, Kazem Nouri, Lech G Milroy, Jens M Moll, Christian Herrmann, Luc Brunsveld, Roland P Piekorz, Mohammad R Ahmadian
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91465 (2014)
Fragile X mental Retardation Protein (FMRP) is a well-known regulator of local translation of its mRNA targets in neurons. However, despite its ubiquitous expression, the role of FMRP remains ill-defined in other cell types. In this study we investig
Externí odkaz:
https://doaj.org/article/7f8f0b5a676e458898981b70a8a74a0b
Autor:
Nils Hampel, Jacqueline Georgy, Mehrnaz Mehrabipour, Alexander Lang, Isabell Lehmkuhl, Jürgen Scheller, Mohammad R. Ahmadian, Doreen M. Floss, Roland P. Piekorz
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2187-2199 (2023)
SIRT4, together with SIRT3 and SIRT5, comprises the mitochondrially localized subgroup of sirtuins. SIRT4 regulates mitochondrial bioenergetics, dynamics (mitochondrial fusion), and quality control (mitophagy) via its NAD+‐dependent enzymatic activ
Externí odkaz:
https://doaj.org/article/3f16df6f448a42b7bf36896ed4596877
Autor:
Saeideh Nakhaei-Rad, Fereshteh Haghighi, Farhad Bazgir, Julia Dahlmann, Alexandra Viktoria Busley, Marcel Buchholzer, Karolin Kleemann, Anne Schänzer, Andrea Borchardt, Andreas Hahn, Sebastian Kötter, Denny Schanze, Ruchika Anand, Florian Funk, Annette Vera Kronenbitter, Jürgen Scheller, Roland P. Piekorz, Andreas S. Reichert, Marianne Volleth, Matthew J. Wolf, Ion Cristian Cirstea, Bruce D. Gelb, Marco Tartaglia, Joachim P. Schmitt, Martina Krüger, Ingo Kutschka, Lukas Cyganek, Martin Zenker, George Kensah, Mohammad R. Ahmadian
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-18 (2023)
Abstract Noonan syndrome (NS), the most common among RASopathies, is caused by germline variants in genes encoding components of the RAS-MAPK pathway. Distinct variants, including the recurrent Ser257Leu substitution in RAF1, are associated with seve
Externí odkaz:
https://doaj.org/article/334fbffc3d50486090984e565b31f40f
Autor:
Neda S. Kazemein Jasemi, Mehrnaz Mehrabipour, Eva Magdalena Estirado, Luc Brunsveld, Radovan Dvorsky, Mohammad R. Ahmadian
Publikováno v:
Cells, Vol 13, Iss 2, p 195 (2024)
SRC homology 3 (SH3) domains are critical interaction modules that orchestrate the assembly of protein complexes involved in diverse biological processes. They facilitate transient protein–protein interactions by selectively interacting with prolin
Externí odkaz:
https://doaj.org/article/c7001b3fff9d4e5b9493001e5111db30
Autor:
Silke Pudewell, Jana Lissy, Hossein Nakhaeizadeh, Niloufar Mosaddeghzadeh, Saeideh Nakhaei-Rad, Radovan Dvorsky, Mohammad R. Ahmadian
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stress-activated MAP kinase-interacting protein 1 (SIN1) is a central member of the mTORC2 complex that contains an N-terminal domain (NTD), a conserved region in the middle (CRIM), a RAS-binding domain (RBD), and a pleckstrin homology domain. Recent
Externí odkaz:
https://doaj.org/article/5d40e5ad25814d9da32bd2c0caba6148
Publikováno v:
Cells, Vol 12, Iss 16, p 2054 (2023)
SRC homology 3 (SH3) domains are fundamental modules that enable the assembly of protein complexes through physical interactions with a pool of proline-rich/noncanonical motifs from partner proteins. They are widely studied modular building blocks ac
Externí odkaz:
https://doaj.org/article/c0c8478fe4e743c4bd4e18a159599ba2
Autor:
Silke Pudewell, Christoph Wittich, Neda S. Kazemein Jasemi, Farhad Bazgir, Mohammad R. Ahmadian
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Pudewell et al. discuss and advance our understanding of accessory proteins, which are crucial for the RTK-RAS-MAPK signalling cascade. They consider the therapeutic potential of targeting such modulators as an alternative to targeting constituent co
Externí odkaz:
https://doaj.org/article/b0d12c1b52df4beda6fee1cbf96887b8