Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Mohammad O Hoque"'
Autor:
Mariana Brait, Leonel Maldonado, Maartje G Noordhuis, Shahnaz Begum, Myriam Loyo, Maria Luana Poeta, Alvaro Barbosa, Vito M Fazio, Roberto Angioli, Carla Rabitti, Luigi Marchionni, Pauline de Graeff, Ate G J van der Zee, G Bea A Wisman, David Sidransky, Mohammad O Hoque
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e70878 (2013)
PURPOSE:To elucidate the role of biological and clinical impact of aberrant promoter hypermethylation (PH) in ovarian cancer (OC). EXPERIMENTAL DESIGN:PH of PGP9.5, HIC1, AIM1, APC, PAK3, MGMT, KIF1A, CCNA1, ESR1, SSBP2, GSTP1, FKBP4 and VGF were ass
Externí odkaz:
https://doaj.org/article/2ab100d75e0c413ab21f75fa8d3ab044
Autor:
Xiaoli Zhong, Sumit Isharwal, Jean M Naples, Clive Shiff, Robert W Veltri, Chunbo Shao, Kwabena M Bosompem, David Sidransky, Mohammad O Hoque
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59089 (2013)
Schistosoma haematobium is associated with chronic bladder damage and may subsequently induce bladder cancer in humans, thus posing a serious threat where the parasite is endemic. Here we evaluated aberrant promoter DNA methylation as a potential bio
Externí odkaz:
https://doaj.org/article/f62d671e782a4d8cb0db54e59c1f1d42
Autor:
Megan L Durr, Wojciech K Mydlarz, Chunbo Shao, Marianna L Zahurak, Alice Y Chuang, Mohammad O Hoque, William H Westra, Nanette J Liegeois, Joseph A Califano, David Sidransky, Patrick K Ha
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10828 (2010)
Methylation profiling of tumor suppressor gene (TSGs) promoters is quickly becoming a powerful diagnostic tool for the early detection, prognosis, and even prediction of clinical response to treatment. Few studies address this in salivary gland tumor
Externí odkaz:
https://doaj.org/article/ac6e9c54c38641f4aa5ff3b9f06610a6
Autor:
Anju Singh, Vikas Misra, Rajesh K Thimmulappa, Hannah Lee, Stephen Ames, Mohammad O Hoque, James G Herman, Stephen B Baylin, David Sidransky, Edward Gabrielson, Malcolm V Brock, Shyam Biswal
Publikováno v:
PLoS Medicine, Vol 3, Iss 10, p e420 (2006)
Nuclear factor erythroid-2 related factor 2 (NRF2) is a redox-sensitive transcription factor that positively regulates the expression of genes encoding antioxidants, xenobiotic detoxification enzymes, and drug efflux pumps, and confers cytoprotection
Externí odkaz:
https://doaj.org/article/bf99d43e16034fc6bac611416d4d67b7
Autor:
Yoshikuni Inokawa, Masamichi Hayashi, Shahnaz Begum, Maartje G. Noordhuis, Daivd Sidransky, Joseph Califano, Wayne Koch, Mariana Brait, William H. Westra, Mohammad O. Hoque
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background HPV-positive oropharyngeal squamous cell carcinomas (OPSCCs) are sensitive to chemo-radiation therapy and have favorable survival outcomes compared with HPV-negative cancers. These tumors are usually not related to tobacco and alc
Externí odkaz:
https://doaj.org/article/51d677fd606a4d56ae1d84b4059ade0d
Publikováno v:
Cancers, Vol 13, Iss 20, p 5098 (2021)
Resistance to cancer therapy remains a significant obstacle in treating patients with various solid malignancies. Exposure to current chemotherapeutics and targeted agents invariably leads to therapy resistance, heralding the need for novel agents. C
Externí odkaz:
https://doaj.org/article/5939a24a260a462e9aa29766d5c72f10
Autor:
Trinity J. Bivalacqua, Charles G. Drake, Alex S. Baras, David J. McConkey, Noah M. Hahn, Mohammad O. Hoque, George J. Netto, Leonardo O. Reis, Christina M. Kochel, Hotaka Matsui, Nikolai A. Sopko, Thomas Nirschl, Max Kates
Flow cytometry gating strategy is outlined. After digestion of tumor infiltrated bladders, samples yielded 1-2 million cells per bladder. A) Live T lymphocyte subpopulations were then gated from spleen tissue, and B) bladder T cells of interest were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a28516db5a71f94f433d77db32a5912
https://doi.org/10.1158/2326-6066.22537631.v1
https://doi.org/10.1158/2326-6066.22537631.v1
Autor:
Trinity J. Bivalacqua, Charles G. Drake, Alex S. Baras, David J. McConkey, Noah M. Hahn, Mohammad O. Hoque, George J. Netto, Leonardo O. Reis, Christina M. Kochel, Hotaka Matsui, Nikolai A. Sopko, Thomas Nirschl, Max Kates
Intravesical bacillus Calmette–Guérin (BCG) immunotherapy is the standard of care in treating non–muscle-invasive bladder cancer, yet its mechanism of action remains elusive. Both innate and adaptive immune responses have been implicated in BCG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cdfa57569b053c19c69a49a053c436a
https://doi.org/10.1158/2326-6066.c.6548501.v1
https://doi.org/10.1158/2326-6066.c.6548501.v1
Autor:
Trinity J. Bivalacqua, Charles G. Drake, Alex S. Baras, David J. McConkey, Noah M. Hahn, Mohammad O. Hoque, George J. Netto, Leonardo O. Reis, Christina M. Kochel, Hotaka Matsui, Nikolai A. Sopko, Thomas Nirschl, Max Kates
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94632deba59d6a7d01b2a02ae2d6df40
https://doi.org/10.1158/2326-6066.22537619.v1
https://doi.org/10.1158/2326-6066.22537619.v1
Autor:
Trinity J. Bivalacqua, Charles G. Drake, Alex S. Baras, David J. McConkey, Noah M. Hahn, Mohammad O. Hoque, George J. Netto, Leonardo O. Reis, Christina M. Kochel, Hotaka Matsui, Nikolai A. Sopko, Thomas Nirschl, Max Kates
(A) Rats 8 weeks post MNU were treated intravesically with MMC, MMC+BCG, and Cisplatin for 6 weeks (n=5 for each group). Bladders were harvested at week 16 and then digested into single cell suspensions and T cell populations analyzed with flow cytom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e69f563171ad6367ffade54d2c67ba7
https://doi.org/10.1158/2326-6066.22537628.v1
https://doi.org/10.1158/2326-6066.22537628.v1