Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mohammad Najeeb Al-Hallak"'
Autor:
Md. Hafiz Uddin, Mohammad Najeeb Al‐Hallak, Husain Yar Khan, Amro Aboukameel, Yiwei Li, Sahar F. Bannoura, Gregory Dyson, Seongho Kim, Yosef Mzannar, Ibrahim Azar, Tanya Odisho, Amr Mohamed, Yosef Landesman, Steve Kim, Rafic Beydoun, Ramzi M. Mohammad, Philip A. Philip, Anthony F. Shields, Asfar S. Azmi
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background The majority of pancreatic ductal adenocarcinoma (PDAC) patients experience disease progression while on treatment with gemcitabine and nanoparticle albumin‐bound (nab)‐paclitaxel (GemPac) necessitating the need for a more eff
Externí odkaz:
https://doaj.org/article/746a7f24c49c48c5878e393d3f6d9f55
Autor:
Philip A. Philip, Ramzi M. Mohammad, Vinod Shidham, Steve Kim, Anteneh Tesfaye, Mohammad Najeeb Al-Hallak, Mandana Kamgar, Gregory Dyson, Amit Mahipal, Dirk Daelemans, Jasper E. Neggers, Amro Aboukameel, Irfana Muqbil, Husain Yar Khan, Asfar S. Azmi
Purpose:Pancreatic ductal adenocarcinoma (PDAC) remains a deadly disease urgently requiring new treatments. Overexpression of the protein transporter exportin-1 (XPO1) leads to mislocalization of tumor-suppressor proteins (TSP) and their inactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c0c767791b9d04d1fc3956be154036
https://doi.org/10.1158/1078-0432.c.6528758
https://doi.org/10.1158/1078-0432.c.6528758
Autor:
Philip A. Philip, Ramzi M. Mohammad, Vinod Shidham, Steve Kim, Anteneh Tesfaye, Mohammad Najeeb Al-Hallak, Mandana Kamgar, Gregory Dyson, Amit Mahipal, Dirk Daelemans, Jasper E. Neggers, Amro Aboukameel, Irfana Muqbil, Husain Yar Khan, Asfar S. Azmi
Legends to supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14403f62b4f835c6da1ae61f2f168c98
https://doi.org/10.1158/1078-0432.22474349
https://doi.org/10.1158/1078-0432.22474349
Autor:
Md. Hafiz Uddin, Amro Aboukameel, Yiwei Li, Husain Yar Khan, Rachel E. Sexton, Sahar Bannoura, Gregory Dyson, Mohammad Najeeb Al-Hallak, Yosef Mzannar, Amr Mohamed, Yosef Landesman, Steve Kim, Rafic Beydoun, Ramzi M. Mohammad, Anthony F. Shields, Asfar S. Azmi
The majority of pancreatic ductal adenocarcinoma (PDAC) patients experience disease progression while on treatment with gemcitabine and nab-Paclitaxel (GemPac) treatment indicating the need for more effective combinations for this recalcitrant diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430553d724fed3aabb909abe76f3d148
https://doi.org/10.1101/2022.03.08.481108
https://doi.org/10.1101/2022.03.08.481108
Autor:
Rachel E. Sexton, Md Hafiz Uddin, Sahar Bannoura, Husain Yar Khan, Yousef Mzannar, Yiwei Li, Amro Aboukameel, Mohammad Najeeb Al-Hallak, Bayan Al-Share, Amr Mohamed, Misako Nagasaka, Bassel El-Rayes, Asfar S. Azmi
Publikováno v:
Cancer metastasis reviewsReferences. 41(2)
Pancreatic cancer is a deadly disease that is increasing in incidence throughout the world. There are no clear causal factors associated with the incidence of pancreatic cancer; however, some correlation to smoking, diabetes and alcohol has been desc
Autor:
Husain Yar Khan, Sahar Bannoura, Hirva Mamdani, Amro Aboukameel, Yousef Mzannar, Yiwei Li, Mohammad Najeeb Al-Hallak, Ibrahim Azar, Steve Kim, Rafic Beydoun, Ramzi Mohammad, Yosef Landesman, Yue Zhang, Erkan Baloglu, William Senapedis, Ammar Sukari, Misako Nagasaka, Anthony Shields, Asfar S. Azmi
Publikováno v:
Cancer Research. 82:5315-5315
Background: KRASG12C inhibitors sotorasib and adagrasib have shown impressive results in clinical studies. These inhibitors efficiently block KRAS downstream effectors such as RAF, MEK, and ERK/p-ERK. However, factors such as feedback reactivation or
Autor:
Rachel E. Sexton, Md Hafz Uddin, Sahar Bannoura, Husain Yar Khan, Yousef Mzannar, Yiwei Li, Amro Aboukameel, Mohammad Najeeb Al-Hallak, Bayan Al-Share, Amr Mohamed, Misako Nagasaka, Bassel El-Rayes, Asfar S. Azmi
Publikováno v:
Cancer and Metastasis Reviews. 41:333-333
Autor:
Yosef Landesman, Keerthana Danasekaran, Trinayan Kashyap, Amro Aboukameel, Asfar S. Azmi, Rachel E. Sexton, Mohammad Najeeb Al-Hallak, Hafiz Uddin, Husain Yar Khan, Yiwei Li
Publikováno v:
Journal of Cancer Science and Clinical Therapeutics.
Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide and the third leading cause of cancer related deaths in the United States with a 5-year survival rate of 63%. Depending on the stage of disease, there are differing rates o
Autor:
Trinayan Kashyap, Amro Aboukameel, Bayan Al-Share, Rachel E. Sexton, Steve Kim, Yosef Landesman, Philip A. Philip, Mohammad Najeeb Al-Hallak, Yiwei Li, Asfar S. Azmi, Ramzi M. Mohammad
Publikováno v:
Cancer Research. 81:2383-2383
The global incidence of gastric cancer exceeds 1 million people per year and has a 5-year survival rate of 31%. Current chemotherapies are not effective because of genetic and epigenetic heterogeneity and late stage detection. Previously, we showed t
Autor:
Dirk Daelemans, Vinod B. Shidham, Amit Mahipal, Amro Aboukameel, Steve Kim, Mandana Kamgar, Jasper E. Neggers, Ramzi M. Mohammad, Philip A. Philip, Mohammad Najeeb Al-Hallak, Asfar S. Azmi, Irfana Muqbil, Gregory Dyson, Anteneh Tesfaye, Husain Yar Khan
Publikováno v:
Clin Cancer Res
Purpose: Pancreatic ductal adenocarcinoma (PDAC) remains a deadly disease urgently requiring new treatments. Overexpression of the protein transporter exportin-1 (XPO1) leads to mislocalization of tumor-suppressor proteins (TSP) and their inactivatio