Potential Efficacy of β-Amyrin Targeting Mycobacterial Universal Stress Protein by In Vitro and In Silico Approach

Autor: Md Amjad Beg, Shivangi, Obaid Afzal, Md Sayeed Akhtar, Abdulmalik S. A. Altamimi, Afzal Hussain, Md Ali Imam, Mohammad Naiyaz Ahmad, Sidharth Chopra, Fareeda Athar

Publikováno v: Molecules, Vol 27, Iss 14, p 4581 (2022)

The emergence of drug resistance and the limited number of approved antitubercular drugs prompted identification and development of new antitubercular compounds to cure Tuberculosis (TB). In this work, an attempt was made to identify potential natura

Externí odkaz: https://doaj.org/article/33597aff753048a6906b105162f01347

Synthesis and evaluation of triazole congeners of nitro-benzothiazinones potentially active against drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy

Autor: Santosh Kumar Sahoo, Mohammad Naiyaz Ahmad, Grace Kaul, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra, Venkata Madhavi Yaddanapudi

Publikováno v: RSC Med Chem

With growing concerns regarding target residue mutation hovering over established anti-TB pharmacophores, it is imperative to have reserve chemotypes at our disposal to curb unrestrained spread of tuberculosis. In this context, we herein present the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ba592e0c5a5bdfae27c33dc6f20b3a
https://doi.org/10.1039/d1md00387a

Tuberculosis: Integrated Studies for a Complex Disease 2050

Autor: Nima Rezaei, Nastaran-Sadat Hosseini, Amene Saghazadeh, Abolfazl Fateh, Adriano Duse, Aijaz Ahmad, Alexander E. Braley, Alican Tahta, Alisha Kamboj, Amer Hayat Khan, Ana Cláudia Coelho, Andrea Fuso, Andrés Varón, Anete Trajman, Anil Kumar Saxena, Ankit Ganeshpurkar, Anthony M. Casapao, Anton Tkachenko, Anushka V. Devnikar, Arfa Moshiri, Arrate Muñoz-Barrutia, Arunava Dasgupta, Arvind Natarajan, Ashish Gupta, Ashlan J. Kunz Coyne, Ashly E. Jordan, Ashok Kumar, Atadzhan Ergeshov, Babak Pourakbari, Basant Joshi, Bibiana Chavarro-Portillo, Carlos Y. Soto, Carly Kanipe, Christiane Mello Schmidt, Christophe Cox, Clara Gómez-Cruz, Claudete Aparecida Araújo Cardoso, Clemax Couto Sant´Anna, Courtney Johnson, Cristhian N. Rodríguez-Silva, Cristian Rosales, Cuauhtémoc Licona-Cassani, Cynthia D. Fast, Damián Pérez-Martínez, Damiano Pizzol, David C. Perlman, Dennis Philips, Diana Viveros, Dina A. Fisher, Dmytro Butov, Eric F. Egelund, Everest de Igartua, Garima Bhatt, Georgies Mgode, Gianluca Quaglio, Giovanni Putoto, G. K. Mini, Govind Thomas-Richardson, Greg Wylie, Guilherme Felipe dos Santos Fernandes, Gustavo Bermúdez, Hélder Quintas, Himanshu Verma, Hyungjin Eoh, Ikhwanuliman Putera, Ilya Sivokozov, Isabel Pires, Jae Jin Lee, Jason E. Lombard, Jean Leandro dos Santos, Jean-Pierre Zellweger, Jenu Thomas-Richardson, Jinbert Lordson, João Lucas Prates, Jorge Cervantes, José M. Porcel, Juan José Vaquero, Justina Prada, Kamal Kamboj, Khalid F. Tabbara, Kirubel Manyazewal Mussie, Krupesh Patel, Laura Porcel, Lena Fiebig, Malu Mohan, Mange Ram Yadav, Marcela López-R, Margarida Correia-Neves, Maria da Conceição Fontes, Maria de Fátima Pombo Bazhuni Sant´Anna, Marina Cañadas-Ortega, Meenakshi Singh, Michael Lause, Milena Maya-Hoyos, Mir Davood Omrani, Mitchell V. Palmer, Mohammad Naiyaz Ahmad, Mohammed Assen Seid, Monica Chauhan, Mridula Saxena, Musa Marimani, Nanduri Srinivas, Negussie Beyene, Nelson E. Arenas, Nicole Cardoso, Olena Oliveira, Om Silakari, Osvaldo Inlamea, Özgür Tanrıverdi, Paola M. Boggiatto, Paola Santos, Paulina Mejía-Ponce, Pedro Soares, Philip Sell, Prashant R. Murumkar, Praveen Devanandan, Qi Zheng, Rachel K. Lim, Rafaela Baroni Aurílio, Rahul B. Ghuge, Rahul R. Barot, null Rahul, Ranadheer Chowdary Puvvada, Raquel Duarte, Ravi Singh, Richa Sinha, Rina La Distia Nora, Robert Burny, Roberto Zenteno-Cuevas, Sagar Mali, Samir S. Shoughy, Samira Tarashi, Sapna Mishra, Satyaveni Malasala, Setareh Mamishi, Seyed Davar Siadat, Shalki Choudhary, Shima Mahmoudi, Sidharth Chopra, Sisir Nandi, Sobia Faisal, Sonu Goel, Stanislav Huszár, Stephen K. Field, Sushil Kumar Singh, Teresa Rito, Tetiana Butova, Thomas Manning, Tjip S. van der Werf, Valeriy Myasoedov, Vanessa Vásquez, Vijey Aanandhi Muthukumar, Vinayak Singh, Walter A. Hall, Wandya Hikmahwati, Yaşar Barış Turgut, Yatri Thaker, Yoshinori Kawabata, Yvette A. de Reus

Publikováno v: Integrated Science ISBN: 9783031159541

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f42d8bf60e80a29de1dee0aaef53f38
https://doi.org/10.1007/978-3-031-15955-8_51

In Vitro and In Vivo Activity of Gepotidacin against Drug-Resistant Mycobacterial Infections

Autor: Mohammad Naiyaz Ahmad, Tanu Garg, Shriya Singh, Richa Shukla, Pradip Malik, Ramya V. Krishnamurthy, Parvinder Kaur, Sidharth Chopra, Arunava Dasgupta

Publikováno v: Antimicrob Agents Chemother

Mycobacterial pathogens, including nontuberculous mycobacteria (NTM) and Mycobacterium tuberculosis, are pathogens of significant worldwide interest owing to their inherent drug resistance to a wide variety of FDA-approved drugs as well as causing a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526f5cd93897a36119df9e7bc01d4b29
https://europepmc.org/articles/PMC9765166/

Identification of 1,3‐Substituted Pyrazole‐Based Carboxamide Derivatives as Potent Antitubercular Agents

Autor: Nikhil Baliram Gaikwad, Santosh Kumar Sahoo, Ojaswitha Ommi, Mohammad Naiyaz Ahmad, Afroz Pathan, Grace Kaul, Srinivas Nanduri, Arunava Dasgupta, Sidharth Chopra, Venkata Madhavi Yaddanapudi

Publikováno v: ChemistrySelect. 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f58cfe4ebf33f65d49f3a87222760f22
https://doi.org/10.1002/slct.202203333