Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mohammad Mehrian"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Stem cell expansion on 3D porous scaffolds cultured in bioreactor systems has been shown to be beneficial for maintenance of the original cell functionality in tissue engineering strategies (TE). However, the production of extracellular matrix (ECM)
Externí odkaz:
https://doaj.org/article/6c53cc4dd9f5409c92327ac0ddb330ca
Autor:
Liesbet Geris, Mohammad Mehrian
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering
Tissue engineering is a fast progressing domain where solutions are provided for organ failure or tissue damage. In this domain, computer models can facilitate the design of optimal production process conditions leading to robust and economically via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8e2417a7787e6e42c8e1f12af803c8
https://pubmed.ncbi.nlm.nih.gov/31996043
https://pubmed.ncbi.nlm.nih.gov/31996043
Autor:
Liesbet Geris, Mohammad Mehrian, Marc Peter Deisenroth, Simon Olofsson, Ruth Misener, Roberto Calandra
Publikováno v:
IEEE Transactions on Biomedical Engineering
Tissue engineering and regenerative medicine looks at improving or restoring biological tissue function in humans and animals. We consider optimising neotissue growth in a three-dimensional scaffold during dynamic perfusion bioreactor culture, in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68026ef64a634492becca5a0f7b57119
Autor:
Ruth Misener, Liesbet Geris, Mohammad Mehrian, Maarten Sonnaert, Ioannis Papantoniou, Simon Olofsson, Yann Guyot
Publikováno v:
Biotechnology and Bioengineering
In regenerative medicine, computer models describing bioreactor processes can assist in designing optimal process conditions leading to robust and economically viable products. In this study, we started from a (3D) mechanistic model describing the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e3e55d1cd2b9d87ed742f061fd7a53
https://lirias.kuleuven.be/handle/20.500.12942/689645
https://lirias.kuleuven.be/handle/20.500.12942/689645
Publikováno v:
Computational Biology and Chemistry. 48:21-28
Exposure-response modeling and simulation is especially useful in oncology as it permits to predict and design un-experimented clinical trials as well as dose selection. Dendritic cells (DC) are the most effective immune cells in the regulation of im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac34e7c40e1e38db247fed40a434154
https://doi.org/10.1016/j.compbiolchem.2013.09.007
https://doi.org/10.1016/j.compbiolchem.2013.09.007
We consider optimising bone neotissue growth in a 3D scaffold during dynamic perfusion bioreactor culture. The goal is to choose design variables by optimising two conflicting objectives: (i) maximising neotissue growth and (ii) minimising operating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa2697ef07b8d71e16621adcb23aaf5
https://doi.org/10.1016/b978-0-444-63965-3.50361-5
https://doi.org/10.1016/b978-0-444-63965-3.50361-5
Autor:
Frank P. Luyten, Liesbet Geris, Toon Lambrechts, Ioannis Papantoniou, Marina Marechal, Mohammad Mehrian
Publikováno v:
Cytotherapy
Background Human mesenchymal stromal cells (hMSCs) have become attractive candidates for advanced medical cell-based therapies. An in vitro expansion step is routinely used to reach the required clinical quantities. However, this is influenced by man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4979c8c5be657a4448e965b67d3ef4