Physics of Brain Cancer: Multiscale Alterations of Glioblastoma Cells under Extracellular Matrix Stiffening

Autor: Mohammad Khoonkari, Dong Liang, Marleen Kamperman, Frank A. E. Kruyt, Patrick van Rijn

Publikováno v: Pharmaceutics, Vol 14, Iss 5, p 1031 (2022)

The biology and physics underlying glioblastoma is not yet completely understood, resulting in the limited efficacy of current clinical therapy. Recent studies have indicated the importance of mechanical stress on the development and malignancy of ca

Externí odkaz: https://doaj.org/article/ef9b51427b0d4227a75a31dd60ae40cf

Bioinspired Processing: Complex Coacervates as Versatile Inks for 3D Bioprinting

Autor: Mohammad Khoonkari, Julien Es Sayed, Marta Oggioni, Armin Amirsadeghi, Daniele Parisi, Frank Kruyt, Patrick van Rijn, Małgorzata Katarzyna Włodarczyk‐Biegun, Marleen Kamperman

Publikováno v: Advanced materials. WILEY-V C H VERLAG GMBH

3D bioprinting is a powerful fabrication technique in biomedical engineering, which is currently limited by the number of available materials that meet all physicochemical and cytocompatibility requirements for biomaterial inks. Inspired by the key r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d130062cbf0888788e10cb925d528112
https://doi.org/10.1002/adma.202210769

The unfolded protein response as regulator of cancer stemness and differentiation: Mechanisms and implications for cancer therapy

Autor: Mohammad Khoonkari, Frank A.E. Kruyt, Eric Chevet, Tony Avril, Dong Liang

Publikováno v: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩
Biochemical Pharmacology, 2021, 192, pp.114737. ⟨10.1016/j.bcp.2021.114737⟩

International audience; The unfolded protein response (UPR) is an adaptive mechanism that regulates protein and cellular homeostasis. Three endoplasmic reticulum (ER) membrane localized stress sensors, IRE1, PERK and ATF6, coordinate the UPR in order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a338143af981480beeebe73580705
https://hal.archives-ouvertes.fr/hal-03334034/document

The Unfolded Protein Response Sensor PERK Mediates Stiffness-Dependent Adaptation in Glioblastoma Cells.

Autor: Khoonkari, Mohammad^1,2 (AUTHOR) jianwu.sun@rug.nl, Liang, Dong¹ (AUTHOR) d.liang01@umcg.nl, Lima, Marina Trombetta³ (AUTHOR) m.trombetta.lima@rug.nl, van der Land, Tjitze⁴ (AUTHOR) t.van.der.land.1@student.rug.nl, Liang, Yuanke^1,5 (AUTHOR) ykliang12345@163.com, Sun, Jianwu² (AUTHOR) marleen.kamperman@rug.nl, Dolga, Amalia³ (AUTHOR) a.m.dolga@rug.nl, Kamperman, Marleen² (AUTHOR), van Rijn, Patrick^4,6 (AUTHOR) p.van.rijn@umcg.nl, Kruyt, Frank A. E.¹ (AUTHOR) p.van.rijn@umcg.nl

Publikováno v: International Journal of Molecular Sciences. Jun2022, Vol. 23 Issue 12, p6520-6520. 19p.

Multi‐Responsive Jammed Micro‐Gels Ink: Toward Control over the Resolution and the Stability of 3D Printed Scaffolds.

Autor: Es Sayed, Julien, Khoonkari, Mohammad, Oggioni, Marta, Perrin, Patrick, Sanson, Nicolas, Kamperman, Marleen, Włodarczyk‐Biegun, Małgorzata Katarzyna

Publikováno v: Advanced Functional Materials; 11/24/2022, Vol. 32 Issue 48, p1-10, 10p