Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mohammad KaramiNejadRanjbar"'
Autor:
Eva Gonçalves Serra, Tobias Schwerd, Loukas Moutsianas, Athena Cavounidis, Laura Fachal, Sumeet Pandey, Jochen Kammermeier, Nicholas M. Croft, Carsten Posovszky, Astor Rodrigues, Richard K. Russell, Farah Barakat, Marcus K. H. Auth, Robert Heuschkel, Matthias Zilbauer, Krzysztof Fyderek, Christian Braegger, Simon P. Travis, Jack Satsangi, Miles Parkes, Nikhil Thapar, Helen Ferry, Julie C. Matte, Kimberly C. Gilmour, Andrzej Wedrychowicz, Peter Sullivan, Carmel Moore, Jennifer Sambrook, Willem Ouwehand, David Roberts, John Danesh, Toni A. Baeumler, Tudor A. Fulga, Mohammad Karaminejadranjbar, Ahmed Ahmed, Rachel Wilson, Jeffrey C. Barrett, Abdul Elkadri, Anne M. Griffiths, COLORS in IBD group investigators, Oxford IBD cohort study investigators, INTERVAL Study, Swiss IBD cohort investigators, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, Scott B. Snapper, Neil Shah, Aleixo M. Muise, David C. Wilson, Holm H. Uhlig, Carl A. Anderson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Adult forms of inflammatory bowel disease (IBD) are of a polygenic nature, but paediatric and very early onset (VEO) IBD also occur as monogenic forms. Here, using whole exome sequencing, the authors explore both the monogenic and polygenic contribut
Externí odkaz:
https://doaj.org/article/2613668b99c441b1b30bfa2765e3a533
Autor:
Mara Artibani, Kenta Masuda, Zhiyuan Hu, Pascal C. Rauher, Garry Mallett, Nina Wietek, Matteo Morotti, Kay Chong, Mohammad KaramiNejadRanjbar, Christos E. Zois, Sunanda Dhar, Salma El-Sahhar, Leticia Campo, Sarah P. Blagden, Stephen Damato, Pubudu N. Pathiraja, Shibani Nicum, Fergus Gleeson, Alexandros Laios, Abdulkhaliq Alsaadi, Laura Santana Gonzalez, Takeshi Motohara, Ashwag Albukhari, Zhen Lu, Robert C. Bast Jr., Adrian L. Harris, Christer S. Ejsing, Robin W. Klemm, Christopher Yau, Tatjana Sauka-Spengler, Ahmed Ashour Ahmed
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Similar to tumor-initiating cells (TICs), minimal residual disease (MRD) is capable of reinitiating tumors and causing recurrence. However, the molecular characteristics of solid tumor MRD cells and drivers of their survival have remained elusive. He
Externí odkaz:
https://doaj.org/article/aed4f3377d6c477db1f5a1a0d72b84ea
Autor:
Kolja N. Eckermann, Stefan Dippel, Mohammad KaramiNejadRanjbar, Hassan M. Ahmed, Ingrid M. Curril, Ernst A. Wimmer
Publikováno v:
BMC Genomic Data, Vol 23, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/56133cb314a545f49c1e84065355d710
Autor:
Yiyan Zheng, Ritika Sethi, Lingegowda S. Mangala, Charlotte Taylor, Juliet Goldsmith, Ming Wang, Kenta Masuda, Mohammad Karaminejadranjbar, David Mannion, Fabrizio Miranda, Sandra Herrero-Gonzalez, Karin Hellner, Fiona Chen, Abdulkhaliq Alsaadi, Ashwag Albukhari, Donatien Chedom Fotso, Christopher Yau, Dahai Jiang, Sunila Pradeep, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Stefan Knapp, Nathanael S. Gray, Leticia Campo, Kevin A. Myers, Sunanda Dhar, David Ferguson, Robert C. Bast, Anil K. Sood, Frank von Delft, Ahmed Ashour Ahmed
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Some anticancer drugs target cell microtubules inhibiting mitosis and cell division. Here, the authors show that CRMP2 induces microtubule bundling and that this activity is regulated by the FER kinase, thus providing a rationale for targeting FER in
Externí odkaz:
https://doaj.org/article/3f3066d1a6b14342a99fe65262e6ce95
Autor:
Karin Hellner, Fabrizio Miranda, Donatien Fotso Chedom, Sandra Herrero-Gonzalez, Daniel M. Hayden, Rick Tearle, Mara Artibani, Mohammad KaramiNejadRanjbar, Ruth Williams, Kezia Gaitskell, Samar Elorbany, Ruoyan Xu, Alex Laios, Petronela Buiga, Karim Ahmed, Sunanda Dhar, Rebecca Yu Zhang, Leticia Campo, Kevin A. Myers, María Lozano, María Ruiz-Miró, Sónia Gatius, Alba Mota, Gema Moreno-Bueno, Xavier Matias-Guiu, Javier Benítez, Lorna Witty, Gil McVean, Simon Leedham, Ian Tomlinson, Radoje Drmanac, Jean-Baptiste Cazier, Robert Klein, Kevin Dunne, Robert C. Bast Jr, Stephen H. Kennedy, Bassim Hassan, Stefano Lise, María José Garcia, Brock A. Peters, Christopher Yau, Tatjana Sauka-Spengler, Ahmed Ashour Ahmed
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 137-149 (2016)
Current screening methods for ovarian cancer can only detect advanced disease. Earlier detection has proved difficult because the molecular precursors involved in the natural history of the disease are unknown. To identify early driver mutations in o
Externí odkaz:
https://doaj.org/article/48848af61fb0476781413217637a8181
Autor:
P N Pathiraja, Nina Wietek, Robin W. Klemm, Matteo Morotti, Kay Chong, Christer S. Ejsing, S Nicum, Fergus V. Gleeson, Christos E. Zois, Zhimin Lu, Robert C. Bast, Kenta Masuda, Stephen Damato, P C Rauher, Christopher Yau, Alexandros Laios, Zhiyuan Hu, Abdulkhaliq Alsaadi, Garry Mallett, L Santana Gonzalez, Takeshi Motohara, Salma El-Sahhar, Leticia Campo, Sunanda Dhar, Adrian L. Harris, Mohammad KaramiNejadRanjbar, Ahmed Ashour Ahmed, Ashwag Albukhari, Sarah P. Blagden, Tatjana Sauka-Spengler, Mara Artibani
Publikováno v:
Artibani, M, Masuda, K, Hu, Z, Rauher, P C, Mallett, G, Wietek, N, Morotti, M, Chong, K, Ranjbar, M K N, Zois, C E, Dhar, S, El-Sahhar, S, Campo, L, Blagden, S P, Damato, S, Pathiraja, P N, Nicum, S, Gleeson, F, Laios, A, Alsaadi, A, Gonzalez, L S, Motohara, T, Albukhari, A, Lu, Z, Bast, R C, Harris, A L, Ejsing, C S, Klemm, R W, Yau, C, Sauka-Spengler, T & Ahmed, A A 2021, ' Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumorinitiating cells ', JCI Insight, vol. 6, no. 11, e147929 . https://doi.org/10.1172/jci.insight.147929
JCI Insight
JCI Insight
Similar to tumor-initiating cells (TICs), minimal residual disease (MRD) is capable of reinitiating tumors and causing recurrence. However, the molecular characteristics of solid tumor MRD cells and drivers of their survival have remained elusive. He
Autor:
Christopher Yau, Sahand Sharifzadeh, Volker Tresp, Ahmed Ashour Ahmed, Tatjana Sauka-Spengler, Mara Artibani, Salma El-Sahhar, Mohammad KaramiNejadRanjbar, Nina Wietek
Publikováno v:
KaramiNejadRanjbar, M, Sharifzadeh, S, Wietek, N C, Artibani, M, El-Sahhar, S, Sauka-Spengler, T, Yau, C, Tresp, V & Ahmed, A A 2020, ' A highly accurate platform for clone-specific mutation discovery enables the study of active mutational processes ', eLife, vol. 9, pp. e55207 . https://doi.org/10.7554/eLife.55207
eLife
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
Bulk whole genome sequencing (WGS) enables the analysis of tumor evolution but, because of depth limitations, can only identify old mutational events. The discovery of current mutational processes for predicting the tumor's evolutionary trajectory re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f263cd7fee7b7732b2020fbed22f31
https://doi.org/10.7554/eLife.55207
https://doi.org/10.7554/eLife.55207
Autor:
Salma El-Sahhar, Christopher Yau, Tatjana Sauka-Spengler, Mohammad KaramiNejadRanjbar, Volker Tresp, Nina Wietek, Ahmed Ashour Ahmed, Sahand Sharifzadeh, Mara Artibani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::394c1518c65237ae20fde9119bec1c29
https://doi.org/10.7554/elife.55207.sa2
https://doi.org/10.7554/elife.55207.sa2
Autor:
Abdulkhaliq Alsaadi, Garry Mallett, Yun Feng, Matteo Morotti, Mara Artibani, Tingyan Shi, Salma El-Sahhar, Nina Wietek, Zhiyuan Hu, Leticia Campo, Christopher Yau, Tatjana Sauka-Spengler, Yiyan Zheng, Kenta Masuda, Stephen Damato, Kay Chong, Zhe Zhong, Mohammad KaramiNejadRanjbar, Vincenzo Cerundolo, Sunanda Dhar, Stephanie Jones, Vikram Singh Rai, Ahmed Ashour Ahmed, Riccardo Garruto Campanile, Laura Santana Gonzalez, Hooman Soleymani Majd, David Maldonado-Perez
Publikováno v:
Hu, Z, Artibani, M, Alsaadi, A, Wietek, N, Morotti, M, Shi, T, Zhong, Z, Santana Gonzalez, L, El-Sahhar, S, KaramiNejadRanjbar, M, Mallett, G, Feng, Y, Masuda, K, Zheng, Y, Chong, K, Damato, S, Dhar, S, Campo, L, Garruto Campanile, R, Soleymani majd, H, Rai, V, Maldonado-Perez, D, Jones, S, Cerundolo, V, Sauka-Spengler, T, Yau, C & Ahmed, A A 2020, ' The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells ', Cancer Cell, vol. 37, no. 2, pp. 226-242.e7 . https://doi.org/10.1016/j.ccell.2020.01.003
The inter-differentiation between cell states promotes cancer cell survival under stress and fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience but its quantification is confounded by genetic heterogeneity. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afb1cecb9db03a53b3a1fa3f243a6bc
https://doi.org/10.1016/j.ccell.2020.01.003
https://doi.org/10.1016/j.ccell.2020.01.003
Autor:
Stefan Dippel, John M. Marshall, Hassan M. M. Ahmed, Mohammad KaramiNejadRanjbar, Kolja N. Eckermann, Ernst A. Wimmer, Héctor M. Sánchez C.
Publikováno v:
KaramiNejadRanjbar, M; Eckermann, KN; Ahmed, HMM; Héctor Sánchez, CM; Dippel, S; Marshall, JM; et al.(2018). Consequences of resistance evolution in a Cas9-based sex conversion-suppression gene drive for insect pest management. Proceedings of the National Academy of Sciences of the United States of America, 115(24), 6189-6194. doi: 10.1073/pnas.1713825115. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/2173g08w
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 24
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 24
The use of a site-specific homing-based gene drive for insect pest control has long been discussed, but the easy design of such systems has become possible only with the recent establishment of CRISPR/Cas9 technology. In this respect, novel targets f