Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mohammad H, Alshaer"'
Autor:
Mohammad H. Alshaer, PharmD, PhD, Roy Williams, MPH, Mays J. Mousa, PharmD, MBA, Kaitlin M. Alexander, PharmD, Kelly L. Maguigan, PharmD, Kayihura Manigaba, PharmD, Nicole Maranchick, PharmD, Bethany R. Shoulders, PharmD, Timothy W. Felton, MBBS, PhD, Sumith K. Mathew, MD, Charles A. Peloquin, PharmD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0993 (2023)
IMPORTANCE:. Sepsis and septic shock are major healthcare problems that need early and appropriate management. OBJECTIVES:. To evaluate the association of daily cefepime pharmacokinetic/pharmacodynamic (PK/PD) parameters with change in Sequential Org
Externí odkaz:
https://doaj.org/article/5bf159a8cfa740ee8799b467d4b4c8cf
Autor:
Nicole F. Maranchick, Jessica Webber, Mohammad H. Alshaer, Timothy W. Felton, Charles A. Peloquin
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1696 (2023)
Background: The objective was to identify associations between beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) targets and Gram-negative bacteria resistance emergence in patients. Methods: Retrospective data were collected between 2016 to 2019 at
Externí odkaz:
https://doaj.org/article/f04399bc18b84c49959109bff8c455cb
Autor:
Nicole F. Maranchick, Mohammad H. Alshaer, Alison G. C. Smith, Teona Avaliani, Mariam Gujabidze, Tinatin Bakuradze, Shorena Sabanadze, Zaza Avaliani, Maia Kipiani, Charles A. Peloquin, Russell R. Kempker
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Tuberculosis meningitis (TBM) is the most lethal form of TB. It is difficult to treat in part due to poor or uncertain drug penetration into the central nervous system (CNS). To help fill this knowledge gap, we evaluated the cerebrospinal
Externí odkaz:
https://doaj.org/article/42c5acdd55164357a1147124e1c4e097
Autor:
Maria A. Mendoza MD, Mohammad H. Alshaer PharmD, PhD, Giovanni Roldan MD, Jose Guillermo Castro MD, David Ashkin MD, Charles A. Peloquin PharmD, Catherine V. Boulanger MD
Publikováno v:
Journal of the International Association of Providers of AIDS Care, Vol 21 (2022)
Background: Tuberculosis (TB) is the leading cause of death in human immunodeficiency virus (HIV)-infected people worldwide. Currently there are no studies examining the use of Rifabutin (RBN) and Dolutegravir (DTG) in co-infected persons. This is a
Externí odkaz:
https://doaj.org/article/31fff5377c7a4841b5fe67945c0a22b7
Autor:
Erin F. Barreto, Andrew D. Rule, Mohammad H. Alshaer, Jason A. Roberts, Mohd Hafiz Abdul Aziz, Marc H. Scheetz, Kristin C. Mara, Paul J. Jannetto, Ognjen Gajic, John C. O’Horo, Kasey R. Boehmer
Publikováno v:
Implementation Science Communications, Vol 2, Iss 1, Pp 1-9 (2021)
Abstract Background Beta-lactams (i.e., penicillins, cephalosporins, carbapenems, monobactams) are the most widely used class of antibiotics in critically ill patients. There is substantial interpatient variability in beta-lactam pharmacokinetics whi
Externí odkaz:
https://doaj.org/article/e7b3dbe583004badb22ad8cb0fb1adc9
Autor:
Gwendolyn M. Pais, Jack Chang, Erin F. Barreto, Gideon Stitt, Kevin J. Downes, Mohammad H. Alshaer, Emily Lesnicki, Vaidehi Panchal, Maria Bruzzone, Argyle V. Bumanglag, Sara N. Burke, Marc H. Scheetz
Publikováno v:
Clin Pharmacokinet
Cefepime is a broad-spectrum fourth-generation cephalosporin with activity against Gram-positive and Gram-negative pathogens. It is generally administered as an infusion over 30-60 min or as a prolonged infusion with infusion times from 3 h to contin
Autor:
Daniel, Van Aartsen, Museveni, Justine, Estomih, Mduma, Stellah G, Mpagama, Mohammad H, Alshaer, Charles A, Peloquin, Buliga, Mujaga, Athanasia, Maro, Jean, Gratz, Margaret, Kosek, Jie, Liu, Elizabeth T, Rogawski McQuade, Eric R, Houpt, Tania A, Thomas, Scott K, Heysell
Publikováno v:
The Lancet Microbe. 3:e408-e416
Enteropathy is prevalent in tuberculosis-endemic areas, and it has been shown to impair intestinal absorptive function; therefore, enteropathogen burden might negatively affect antimycobacterial pharmacokinetics, particularly among malnourished child
Autor:
Erin F. Barreto, Pooja N. Chitre, Kathleen H. Pine, Kathryn K. Shepel, Andrew D. Rule, Mohammad H. Alshaer, Mohd Hafiz Abdul Aziz, Jason A. Roberts, Marc H. Scheetz, Sara E. Ausman, Lindsay N. Moreland-Head, Christina G. Rivera, Paul J. Jannetto, Kristin C. Mara, Kasey R. Boehmer
Publikováno v:
Therapeutic Drug Monitoring.
Autor:
Daniel S. Graciaa, Maia Kipiani, Matthew J. Magee, Lali Mikiashvili, Ketevan Barbakadze, Nino Bablishvili, Sara C. Auld, Wael A. Alghamdi, Mohammad H. Alshaer, Charles A. Peloquin, Zaza Avaliani, Henry M. Blumberg, Russell R. Kempker
Publikováno v:
Antimicrob Agents Chemother
Although linezolid is effective for multidrug-resistant TB (MDR-TB) tuberculosis treatment, it is associated with cytopenias after 4 weeks of administration. Data on toxicities with long-term use of linezolid and drug pharmacodynamics in MDR-TB treat
Autor:
Sara Ausman, Kasey Boehmer, Pooja Chitre, Kathleen H Pine, Omar M Abu Saleh, Hafiz Abdul-Aziz, Mohammad H Alshaer, Ognjen Gajic, Paul J Jannetto, Kristin Mara, Lindsay Moreland-Head, Christina G Rivera, Jason Roberts, Andrew D Rule, Marc H Scheetz, Kathryn Shepel, Erin F Barreto
Publikováno v:
Open Forum Infectious Diseases. 9
Background Beta-lactam therapeutic drug monitoring (BL TDM; drug level testing) can facilitate improved outcomes in critically ill patients. Yet less than 20% of hospitals have implemented BL TDM. The purpose of this study was to characterize provide