Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Mohammad F Kiani"'
Autor:
Jordan C Langston, Michael T Rossi, Qingliang Yang, William Ohley, Edwin Perez, Laurie E Kilpatrick, Balabhaskar Prabhakarpandian, Mohammad F Kiani
Publikováno v:
Vascular Biology, Vol 4, Iss 1, Pp R15-R34 (2022)
During sepsis, defined as life-threatening organ dysfunction due to dysregulated host response to infection, systemic inflammation activates endothelial cells and initiates a multifaceted cascade of pro-inflammatory signaling events, resulting in inc
Externí odkaz:
https://doaj.org/article/95cdab2dcca64d429a1149bc75f259c8
Autor:
Xiaoyi Zheng, Fariborz Soroush, Jin Long, Evan T Hall, Puneeth K Adishesha, Sanchita Bhattacharya, Mohammad F Kiani, Vivek Bhalla
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185250 (2017)
Diabetic nephropathy (DN) is the leading cause of kidney disease; however, there are no early biomarkers and no cure. Thus, there is a large unmet need to predict which individuals will develop nephropathy and to understand the molecular mechanisms t
Externí odkaz:
https://doaj.org/article/12f64a90f16e43c4ad6965dd57d96bd2
Autor:
Sudhir P Deosarkar, Balabhaskar Prabhakarpandian, Bin Wang, Joel B Sheffield, Barbara Krynska, Mohammad F Kiani
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142725 (2015)
Studies of neonatal neural pathologies and development of appropriate therapeutics are hampered by a lack of relevant in vitro models of neonatal blood-brain barrier (BBB). To establish such a model, we have developed a novel blood-brain barrier on a
Externí odkaz:
https://doaj.org/article/1576842059894909bb1e15dc22952f10
Autor:
Qingliang Yang, Jordan C. Langston, Roman Prosniak, Samantha Pettigrew, Huaqing Zhao, Edwin Perez, Hannah Edelmann, Nadia Mansoor, Carmen Merali, Salim Merali, Nathaniel Marchetti, Balabhaskar Prabhakarpandian, Mohammad F. Kiani, Laurie E. Kilpatrick
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeSepsis is a clinical syndrome defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis is a highly heterogeneous syndrome with distinct phenotypes that impact immune function and response to inf
Externí odkaz:
https://doaj.org/article/4a549513b5354850bcc150fe7987e872
Autor:
Dan Liu, Jordan C. Langston, Balabhaskar Prabhakarpandian, Mohammad F. Kiani, Laurie E. Kilpatrick
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
Sepsis is a global health concern accounting for more than 1 in 5 deaths worldwide. Sepsis is now defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis can develop from bacterial (gram negative or g
Externí odkaz:
https://doaj.org/article/2075bf0ecf0a44f586a6623f3f920686
Publikováno v:
Shock. 59:224-231
Sepsis is a major health issue and a leading cause of death in hospitals globally. The treatment of sepsis is largely supportive and there are no therapeutics available that target the underlying pathophysiology of the disease. The development of the
Autor:
Qingliang Yang, Harshani Wijerathne, Jordan C. Langston, Mohammad F. Kiani, Laurie E. Kilpatrick
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7770 (2021)
The endothelium is the inner layer of all blood vessels and it regulates hemostasis. It also plays an active role in the regulation of the systemic inflammatory response. Systemic inflammatory disease often results in alterations in vascular endothel
Externí odkaz:
https://doaj.org/article/c34f57b236214d4ba7a530a9d97e4d56
Publikováno v:
Shock
Sepsis is a life-threatening syndrome of organ dysfunction caused by a dysregulated host response to infection characterized by excessive neutrophil infiltration into vital organs. In sepsis, patients often die of organ failure and therapies directed
Autor:
Mohammad F. Kiani, Laurie E. Kilpatrick, Balabhaskar Prabhakarpandian, Yuan Tang, Jordan C. Langston, Qingliang Yang
Publikováno v:
Journal of Visualized Experiments.
Leukocyte-endothelial cell interactions play an important role in inflammatory diseases such as sepsis. During inflammation, excessive migration of activated leukocytes across the vascular endothelium into key organs can lead to organ failure. A phys
Autor:
Peyman Beigi, Ali Allahgholipour, Jamshid S. Khorashad, Mohammad F. Kiani, Negar Goudarzi, Seyed Mohammadreza Bolandi, Anna M. Eiring, Mahdi Pakjoo
Publikováno v:
Cells
Cells, Vol 10, Iss 2833, p 2833 (2021)
Cells, Vol 10, Iss 2833, p 2833 (2021)
Acute myeloid leukemia (AML) is a heterogeneous disease with a poor prognosis and remarkable resistance to chemotherapeutic agents. Understanding resistance mechanisms against currently available drugs helps to recognize the therapeutic obstacles. Va