Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mohammad Behforouz"'
Autor:
Wen Cai, Mary Hassani, Nicholas G. Hermann, Anthony S. Rose, Jennifer S. Lucas, Thomas J. Eads, Ervin D. Walter, Minoo Sedighi, Sahba Charkhzarrin, Katherine H. Koelsch, Mohammad Behforouz, Hamid Mirzaei, Fatemeh Olang, Howard D. Beall, Hassan Seradj, Rajesh Karki, Jayana P. Lineswala, Jeremy S. York
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1899-1909
A series of lavendamycin analogues with two, three or four substituents at the C-6, C-7 N, C-2′, C-3′ and C-11′ positions were synthesized via short and efficient methods and evaluated as potential NAD(P)H:quinone oxidoreductase (NQO1)-directed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1216665b2bf05aa18601a35f725778f6
https://doi.org/10.1016/j.bmc.2010.01.037
https://doi.org/10.1016/j.bmc.2010.01.037
Autor:
Howard D. Beall, Jayana P. Lineswala, William Glen Holloway, Wen Cai, Fatemeh Olang, Mohammad Behforouz, John M. Gerdes, Katherine H. Koelsch, David C. Holley, Mary Hassani, Anthony S. Rose
Publikováno v:
Journal of Medicinal Chemistry. 51:3104-3115
A 1H69 crystal structure-based in silico model of the NAD(P)H:quinone oxidoreductase 1 (NQO1) active site has been developed to facilitate NQO1-directed lavendamycin antitumor agent development. Lavendamycin analogues were designed as NQO1 substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b17e014a7ec0d780a03a98a1fd2fa12
https://doi.org/10.1021/jm701066a
https://doi.org/10.1021/jm701066a
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 60:111-120
FT Raman and FTIR spectra of Naphthazarin (5,8-dihydroxy-1,4-naphthoquinone) and its deuterated analogue are recorded. Comparison between the spectra obtained by two techniques, a series of density functional theory (DFT) calculations and the spectra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4305b75025695871e29199aaeee1836c
https://doi.org/10.1016/s1386-1425(03)00186-0
https://doi.org/10.1016/s1386-1425(03)00186-0
Autor:
Nancy C. Behforouz, Aiqin Wang, Wen Cai, Kevin S. Katen, Daniel Briere, Mark G. Stocksdale, Mohammad Behforouz, Joo Yong Jung, Jennifer S. Lucas
Publikováno v:
Journal of Medicinal Chemistry. 46:5773-5780
Novel lavendamycins including two water soluble derivatives were synthesized via short and efficient methods. Pictet-Spengler condensation of 7-N-acylamino-2-formylquinoline-5,8-diones with tryptophans produced lavendamycin esters or amides 11-17. La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a814ac2ca9de06f09b08854383dfba96
https://doi.org/10.1021/jm0304414
https://doi.org/10.1021/jm0304414
Publikováno v:
Tetrahedron. 56:5259-5288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0927202681be764994ae218c5718d447
https://doi.org/10.1016/s0040-4020(00)00259-3
https://doi.org/10.1016/s0040-4020(00)00259-3
Publikováno v:
The Journal of Organic Chemistry. 63:343-346
Room-temperature acid-catalyzed methanolysis of 7-formamido-, 7-acetamido-, or 7-isobutyramido-2-methylquinoline-5,8-diones (3, 4, 5) gives good to excellent yields of 7-amino-2-methylquinoline-5,8-dione (6). Simple methods for the synthesis of novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3154ec1246ecd8361b6620f83ad3cd5
https://doi.org/10.1021/jo971823i
https://doi.org/10.1021/jo971823i
Autor:
John A. Scherschel, Lindsay S. Stelzer, Mohammad Behforouz, Mohammad Reza Ahmadian, Jalal Haddad, Zhengxiang Gu
Publikováno v:
Tetrahedron Letters. 38:2211-2214
Novel 1-(t-butyldimethylsilyloxy)-1-aza-1,3-butadienes 1 and 2 are prepared by the reaction of O-(t-butyldimethylsilyloxy)hydroxylamine with methyl vinyl ketone and methacrolein, respectively. Azadienes 1 and 2 through sharing of oxygen nonbonding el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd1eb5348c4d4ab55eb304c86d25e61
https://doi.org/10.1016/s0040-4039(97)00326-2
https://doi.org/10.1016/s0040-4039(97)00326-2
Autor:
Aron Sousa, Jalal Haddad, Macklin B. Arnold, Mohammad Behforouz, Wen Cai, Farahnaz Mohammadi, Mark A. Horn
Publikováno v:
The Journal of Organic Chemistry. 61:6552-6555
The novel 7-(N-formyl-, 7-(N-acetyl-, and 7-(N-isobutyrylamino)-2-methylquinoline-5,8-diones were synthesized in excellent overall yields in three steps via the nitration of the commercially available 8-hydroxy-2-methylquinoline followed by a reducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b820f18869df34c00a0c859537cf3a
https://doi.org/10.1021/jo960794t
https://doi.org/10.1021/jo960794t
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa7a7e40371123e96728bc50332b478
https://doi.org/10.1002/chin.199237297
https://doi.org/10.1002/chin.199237297
Publikováno v:
ChemInform. 25
Lavendamycin methyl ester (2), an antitumor antibiotic, was synthesized by a practical and short route in an excellent overallyield of 33% from known starting materials. Pictet-Spengler condensation of 7-acetamido-2-formylquinoline-5,8-dione (4) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95432711370a6274b766ed6965262408
https://doi.org/10.1002/chin.199416278
https://doi.org/10.1002/chin.199416278