Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mohammad Bakhutma"'
Autor:
Antanina Voit, Vishwendra Patel, Ronald Pachon, Vikas Shah, Mohammad Bakhutma, Erik Kohlbrenner, Joseph J. McArdle, Louis J. Dell’Italia, Jerry R. Mendell, Lai-Hua Xie, Roger J. Hajjar, Dongsheng Duan, Diego Fraidenraich, Gopal J. Babu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Sarcolipin is an inhibitor of the ATP dependent calcium pump SERCA, and is abnormally elevated in Duchenne muscular dystrophy. The authors show that reducing sarcolipin expression ameliorates skeletal muscle pathology and cardiomyopathy and extends l
Externí odkaz:
https://doaj.org/article/201501e20c1241caab7a1010c329171a
Autor:
Louis J. Dell'Italia, Antanina Voit, Vishwendra Patel, Dongsheng Duan, Joseph J. McArdle, Ronald Pachon, Lai-Hua Xie, Erik Kohlbrenner, Jerry R. Mendell, Gopal J. Babu, Mohammad Bakhutma, Vikas Shah, Diego Fraidenraich, Roger J. Hajjar
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Sarcolipin (SLN) is an inhibitor of the sarco/endoplasmic reticulum (SR) Ca2+ ATPase (SERCA) and is abnormally elevated in the muscle of Duchenne muscular dystrophy (DMD) patients and animal models. Here we show that reducing SLN levels ameliorates d