Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mohammad Bagher Shahsavani"'
Autor:
Anis Barati, Leila Rezaei Somee, Mohammad Bagher Shahsavani, Atiyeh Ghasemi, Masaru Hoshino, Jun Hong, Ali Akbar Saboury, Ali Akbar Moosavi-Movahedi, Giulio Agnetti, Reza Yousefi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The substitution of leucine to proline at position 39 (p.P39L) in human αB-crystallin (αB-Cry) has been associated with conflicting interpretations of pathogenicity in cataracts and cardiomyopathy. This study aimed to investigate the effec
Externí odkaz:
https://doaj.org/article/872c6124bb044f8cb49a8c3a62b11322
Autor:
Behnaz Mirzaei-Behbahani, Ali Akbar Meratan, Beitollah Moosakhani, Mahya Mohammad-Zaheri, Zahra Mousavi-Jarrahi, Nasser Nikfarjam, Mohammad Bagher Shahsavani, Ali Akbar Saboury
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Green tea polyphenols (GTPs), particularly epigallocatechin-3-gallate, stand out among natural small molecules screened for their ability to target protein aggregates due to their potent anti-amyloidogenic and neuroprotective activities agai
Externí odkaz:
https://doaj.org/article/a05b0ee1006e493f962acc9511317d7c
Autor:
Samaneh Ahmadi, Mohammad Bagher Shahsavani, Zohreh Tavaf, Rawayh Muslim Albaghlany, Ashutosh Kumar, Ali Akbar Moosavi-Movahedi, Reza Yousefi
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Nowadays, a small number of incretin mimics are used to treat type 2 diabetes mellitus (T2DM) due to their longer half-life. The present study aimed to introduce a novel method for producing the liraglutide precursor peptide (LPP) and developing a po
Externí odkaz:
https://doaj.org/article/929a02986a2544da938f157b5ccac695
Autor:
Fatemeh Mamashli, Ali Akbar Meratan, Atiyeh Ghasemi, Nahal Obeidi, Bahram Salmani, Deyhim Atarod, Mitra Pirhaghi, Faezeh Moosavi-Movahedi, Mahya Mohammad-Zaheri, Mohammad Bagher Shahsavani, Zahra Habibi-Kelishomi, Bahram Goliaei, Mahdi Gholami, Ali Akbar Saboury
Publikováno v:
ACS Chemical Neuroscience. 14:851-863
Autor:
Fatemeh Khosravi, Mansi Upadhyay, Ashutosh Kumar, Mohammad Bagher Shahsavani, Mohsen Akbarian, Haniyeh Najafi, Ali Mohammad Tamaddon, Reza Yousefi
Publikováno v:
Journal of Biotechnology. 346:35-46
With the rapid spread of diabetes in human society, the demand for insulin and its precursor (proinsulin) continues to rise. Therefore, the introduction of new methods for their production is essential. In the present study, human proinsulin, while l
Publikováno v:
International Journal of Biological Macromolecules. 242:124590
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1870(7)
Previous research has shown that production of the high levels of oxidants overwhelms the body's antioxidant defense system during diabetes mellitus. Under this circumstance, ocular lens proteins are one of the main molecular targets for oxidative da
Autor:
Samaneh Ahmadi, Mohammad Bagher Shahsavani, Zohreh Tavaf, Rawayh Muslim Albaghlany, Ashutosh Kumar, Ali Akbar Moosavi-Movahedi, Reza Yousefi
Publikováno v:
PloS one. 17(5)
Nowadays, a small number of incretin mimics are used to treat type 2 diabetes mellitus (T2DM) due to their longer half-life. The present study aimed to introduce a novel method for producing the liraglutide precursor peptide (LPP) and developing a po
Autor:
Kazem Khoshaman, Maryam Ghahramani, Mohammad Bagher Shahsavani, Ali Akbar Moosavi-Movahedi, Boris I. Kurganov, Reza Yousefi
Publikováno v:
Biophysical chemistry. 282
Glycine to serine substitution at position 154 of human αB-crystallin (αB-Cry) is behind the development of cardiomyopathy and late-onset distal myopathy. The current study was conducted with the aim to investigate the structural and functional fea
Autor:
Mohammad Mehdi Ghanbarnezhad, Mohammad Bagher Shahsavani, Pramod S. Mali, Mansi Upadhyay, Ashutosh Kumar, Rawayh Muslim Albaghlani, Ali Niazi, Reza Yousefi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1866:130150
Among the various treatments, GLP-1 receptor agonists (incretin mimics) such as liraglutide and exenatide have been well received in treating type 2 diabetes mellitus (T2DM) and obesity. In this study, an exenatide analogue, in which methionine at po