Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Mohammad AlYamani"'
Autor:
Sultan Alshehri, Rehab Alshammari, Mohammad Alyamani, Rufaidah Dabbagh, Bander Almalki, Omamah Aldosari, Renad Alsowayigh, Amirah Alkudeer, Fatimah Aldosari, Jumana Sabr, Faiyaz Shakeel
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 4, Pp 605-616 (2023)
This observational descriptive study that was carried out with the objective of exploring the contribution of the local pharmaceutical industry to the Saudi drug security. Using a drug formulary provided from the Saudi Food and Drug Authority, contai
Externí odkaz:
https://doaj.org/article/59f665207c4e400c90193747102c05c8
Autor:
Mohammad Alyamani, Patrick Michael, Daniel Hettel, Lewis Thomas, Scott D. Lundy, Mike Berk, Mona Patel, Jianbo Li, Hooman Rashidi, Jesse K. McKenney, Eric A. Klein, Nima Sharifi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
BACKGROUND Generally, clinical assessment of gonadal testosterone (T) in human physiology is determined using concentrations measured in peripheral blood. Prostatic T exposure is similarly thought to be determined from peripheral T exposure. Despite
Externí odkaz:
https://doaj.org/article/cb9eecfac3654ec18ebc89de894e1654
Autor:
Mohammad Alyamani, Sultan Alshehri, Prawez Alam, Shahid Ud Din Wani, Mohammed M. Ghoneim, Faiyaz Shakeel
Publikováno v:
Alexandria Engineering Journal, Vol 61, Iss 11, Pp 9119-9128 (2022)
The solubility of the poorly soluble drug raloxifene hydrochloride (3) in binary {dimethyl sulfoxide (DMSO) (1) + water (2)} mixtures have been recorded at several temperatures under atmospheric pressure. Four different computational models were appl
Externí odkaz:
https://doaj.org/article/fad898538fdf4862b11b832855a35767
Autor:
Di Cui, Jianneng Li, Ziqi Zhu, Michael Berk, Aimalie Hardaway, Jeffrey McManus, Yoon-Mi Chung, Mohammad Alyamani, Shelley Valle, Ritika Tiwari, Bangmin Han, Maryam Goudarzi, Belinda Willard, Nima Sharifi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
After androgen deprivation, prostate cancer frequently becomes castration resistant (CRPC), with intratumoral androgen production from extragonadal precursors that activate the androgen receptor pathway. 3β-Hydroxysteroid dehydrogenase-1 (3βHSD1) i
Externí odkaz:
https://doaj.org/article/35efcccf9f7f4527b57a4702b4953aac
Autor:
Amnah Alamer, Syed Mohammed Basheeruddin Asdaq, Mohammad AlYamani, Hussain AlGhadeer, Zahra H. Alnasser, Zainab Aljassim, Maryam Albattat, Ahmed Alhajji, Ahmed Alrashed, Yahya Mohzari, Abrar Aledrees, Badr Almuhainy, Ivo Abraham, Ahmad Alamer
Publikováno v:
Annals of Saudi Medicine, Vol 42, Iss 3, Pp 165-173 (2022)
BACKGROUND: About 5-10% of coronavirus disease 2019 (COVID-19) infected patients require critical care hospitalization and a variety of respiratory support, including invasive mechanical ventilation. Several nationwide studies from Saudi Arabia have
Externí odkaz:
https://doaj.org/article/d7e2944ce7894d7c91d0909fadd24976
Autor:
Xiuxiu Li, Michael Berk, Christopher Goins, Mohammad Alyamani, Yoon-Mi Chung, Chenyao Wang, Monaben Patel, Nityam Rathi, Ziqi Zhu, Belinda Willard, Shaun Stauffer, Eric Klein, Nima Sharifi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Prostate cancer is highly dependent on androgens and the androgen receptor (AR). Hormonal therapies inhibit gonadal testosterone production, block extragonadal androgen biosynthesis, or directly antagonize AR. Resistance to medical castration occurs
Externí odkaz:
https://doaj.org/article/d2278fb65c7b4d3d983deade5ad87986
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224081 (2019)
Steroid hormones and their respective nuclear receptors are essential mediators in numerous physiologic and pathophysiologic processes, ranging from regulation of metabolism, immune function, and reproductive processes to the development of hormone-d
Externí odkaz:
https://doaj.org/article/fc38b79f00c646ed98ab7326ac3146d8
Autor:
Jianneng Li, Mohammad Alyamani, Ao Zhang, Kai-Hsiung Chang, Michael Berk, Zhenfei Li, Ziqi Zhu, Marianne Petro, Cristina Magi-Galluzzi, Mary-Ellen Taplin, Jorge A Garcia, Kevin Courtney, Eric A Klein, Nima Sharifi
Publikováno v:
eLife, Vol 6 (2017)
Prostate cancer is driven by androgen stimulation of the androgen receptor (AR). The next-generation AR antagonist, enzalutamide, prolongs survival, but resistance and lethal disease eventually prevail. Emerging data suggest that the glucocorticoid r
Externí odkaz:
https://doaj.org/article/7124e2fdf77d463d93e84cdc2c13fa4f
Autor:
R. Bruce Montgomery, Mary-Ellen Taplin, Peter S. Nelson, Phillip W. Kantoff, Steven P. Balk, Trevor N. Penning, Daniel Tamae, Alvin M. Matsumoto, Massimo Loda, Lawrence D. True, Roman Gulati, Jonathan L. Wright, Nima Sharifi, Brett T. Marck, Sean Green, Arja Kaipainen, Mohammad Alyamani, Ailin Zhang, Eunpi Cho, Elahe A. Mostaghel
Purpose: Germline variation in solute carrier organic anion (SLCO) genes influences cellular steroid uptake and is associated with prostate cancer outcomes. We hypothesized that, due to its steroidal structure, the CYP17A inhibitor abiraterone may un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960aedcb2cca87f10c90a90458710829
https://doi.org/10.1158/1078-0432.c.6525417.v1
https://doi.org/10.1158/1078-0432.c.6525417.v1
Autor:
R. Bruce Montgomery, Mary-Ellen Taplin, Peter S. Nelson, Phillip W. Kantoff, Steven P. Balk, Trevor N. Penning, Daniel Tamae, Alvin M. Matsumoto, Massimo Loda, Lawrence D. True, Roman Gulati, Jonathan L. Wright, Nima Sharifi, Brett T. Marck, Sean Green, Arja Kaipainen, Mohammad Alyamani, Ailin Zhang, Eunpi Cho, Elahe A. Mostaghel
Supplementary Figures and Tables Supplementary Table S1. Baseline Patient Demographic and Clinical Characteristics Supplementary Table S2. Observed and Expected Hardy Weinberg (HW) Frequency of SLCO Genotypes Supplementary Table S3. Distribution of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1732ed920ab277aece5c680c22c57ee3
https://doi.org/10.1158/1078-0432.22463487.v1
https://doi.org/10.1158/1078-0432.22463487.v1