Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mohammad Afaque Alam"'
Autor:
Chenxiao Wang, Mst Shamima Khatun, Calder R. Ellsworth, Zheng Chen, Mohammad Islamuddin, Ana Karina Nisperuza Vidal, Mohammad Afaque Alam, Shumei Liu, Janet E. Mccombs, Nicholas J. Maness, Robert V. Blair, Jay K. Kolls, Xuebin Qin
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Toll-like receptor 7 (Tlr7) deficiency-accelerated severe COVID-19 is associated with reduced production of interferons (IFNs). However, the underlying mechanisms remain elusive. To address these questions, we utilize Tlr7 and Irf7 deficienc
Externí odkaz:
https://doaj.org/article/5e54acc9b17c45a78d7bba3cb4b56d54
Autor:
Mohammad Afaque Alam, Maurizio Caocci, Mi Ren, Zheng Chen, Fengming Liu, Mst Shamima Khatun, Jay K. Kolls, Xuebin Qin, Tricia H. Burdo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12871 (2023)
Within arterial plaque, HIV infection creates a state of inflammation and immune activation, triggering NLRP3/caspase-1 inflammasome, tissue damage, and monocyte/macrophage infiltration. Previously, we documented that caspase-1 activation in myeloid
Externí odkaz:
https://doaj.org/article/5d52e92326934d7bae911d8b0a4237d7
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background Macrophage migration inhibitory factor (MIF) has been implicated as a protective factor in the development of bronchopulmonary dysplasia (BPD) and is known to be regulated by MicroRNA-451 (miR-451). The aim of this study was to ev
Externí odkaz:
https://doaj.org/article/01c3096316d74ea0a97badeb293dbb62
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/d94216f3259f4f1d9bfd23844a94ea11
Autor:
Mohammad Afaque Alam, Prasun K. Datta
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Excitatory amino acid transporter 2 (EAAT2) is the predominant astrocyte glutamate transporter involved in the reuptake of the majority of the synaptic glutamate in the mammalian central nervous system (CNS). Gene expression can be altered without ch
Externí odkaz:
https://doaj.org/article/703b569ea2094c24baa78bdce07f93df
Autor:
Sushma Chaubey, Sam Thueson, Devasena Ponnalagu, Mohammad Afaque Alam, Ciprian P. Gheorghe, Zubair Aghai, Harpreet Singh, Vineet Bhandari
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-26 (2018)
Abstract Background Mesenchymal stem cells (MSCs) are promising tools for the treatment of human lung disease and other pathologies relevant to newborn medicine. Recent studies have established MSC exosomes (EXO), as one of the main therapeutic vecto
Externí odkaz:
https://doaj.org/article/6b1bfdf36c284ba9af1850ea7871cba3
Autor:
Catherine Gebhard, Eric Rhéaume, Colin Berry, Geneviève Brand, Anne-Elen Kernaleguen, Gabriel Théberge-Julien, Mohammad Afaque Alam, Candace Y W Lee, Laurianne Boileau, Malorie Chabot-Blanchet, Marie-Claude Guertin, Marc-André Lavoie, Jean Grégoire, Réda Ibrahim, Philippe L'Allier, Jean-Claude Tardif
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0168448 (2017)
High-density lipoproteins (HDL) favorably affect endothelial progenitor cells (EPC). Circulating progenitor cell level and function are impaired in patients with acute coronary syndrome (ACS). This study investigates the short-term effects of reconst
Externí odkaz:
https://doaj.org/article/2eea69972c314c95ab6d7ec8d3ade561
Autor:
Bertal H. Aktas, Richard S. Vander Heide, Haoran Yang, Cecily C. Midkiff, Kun Han, Zhongnan Qin, Giovanni Piedimonte, Naoki Iwanaga, Jay K. Kolls, Mohammad Afaque Alam, Robert V Blair, Fengming Liu, Xuebin Qin, Franck Mauvais-Jarvis, Süleyman Ergün, Joseph Mudd, Chenxiao Wang, Joshua M Currey, Jibao He, Nicholas J. Maness, Jay Rappaport, Ronald S. Veazey, Ren Mi
Publikováno v:
Theranostics
Rationale: Pulmonary vascular endotheliitis, perivascular inflammation, and immune activation are observed in COVID-19 patients. While the initial SARS-CoV-2 infection mainly infects lung epithelial cells, whether it also infects endothelial cells (E
Publikováno v:
Pediatric Research. 86:579-588
Background Hyperoxia-induced acute lung injury (HALI) is characterized by increased permeability and infiltration of inflammatory cells, impairment of alveolar development, and compromised lung function. Recent evidence has determined that microRNAs
Autor:
Prasun K. Datta, Mohammad Afaque Alam
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology, Vol 10 (2019)
Excitatory amino acid transporter 2 (EAAT2) is the predominant astrocyte glutamate transporter involved in the reuptake of the majority of the synaptic glutamate in the mammalian central nervous system (CNS). Gene expression can be altered without ch