Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mohammad Aarif Siddiqui"'
Autor:
Vignesh Ramesh, Paradesi Naidu Gollavilli, Luisa Pinna, Mohammad Aarif Siddiqui, Adriana Martinez Turtos, Francesca Napoli, Yasmin Antonelli, Aldo Leal‐Egaña, Jesper Foged Havelund, Simon Toftholm Jakobsen, Elisa Le Boiteux, Marco Volante, Nils Joakim Færgeman, Ole N Jensen, Rasmus Siersbæk, Kumar Somyajit, Paolo Ceppi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp n/a-n/a (2023)
Abstract The epithelial‐to‐mesenchymal transition (EMT) plays a central role in the development of cancer metastasis and resistance to chemotherapy. However, its pharmacological treatment remains challenging. Here, we used an EMT‐focused integr
Externí odkaz:
https://doaj.org/article/f6a02b7c4b9e494a97d706c0ba7228b7
Autor:
Vignesh Ramesh, Paradesi Naidu Gollavilli, Luisa Pinna, Mohammad Aarif Siddiqui, Simon Toftholm Jakobsen, Elisa Le Boiteux, Karen Ege Olsen, Ole Nørregaard Jensen, Rasmus Siersbæk, Kumar Somyajit, Paolo Ceppi
Epithelial to mesenchymal transition (EMT) is a developmental cellular program driving metastasis and chemo-resistance in cancer, but its pharmacological treatment has been so far challenging. Targeting deregulated metabolic processes in cancer is em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229a5b93a3c21e71de0a819e454b6871
https://doi.org/10.1101/2023.01.19.524677
https://doi.org/10.1101/2023.01.19.524677
Autor:
Mohammad Aarif Siddiqui, Barbara Guerra, Maja Dembic, Paolo Ceppi, Isabel Dominguez, Brage S. Andresen
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 6, Pp 1177-1198 (2020)
Guerra, B, Dembic, M, Siddiqui, M A, Dominguez, I, Ceppi, P & Andresen, B S 2020, ' Down-regulation of CK2α leads to up-regulation of the cyclin-dependent kinase inhibitor p27KIP1 in conditions unfavorable for the growth of myoblast cells ', Cellular Physiology and Biochemistry, vol. 54, no. 6, pp. 1177-1198 . https://doi.org/10.33594/000000308
Guerra, B, Dembic, M, Siddiqui, M A, Dominguez, I, Ceppi, P & Andresen, B S 2020, ' Down-regulation of CK2α leads to up-regulation of the cyclin-dependent kinase inhibitor p27KIP1 in conditions unfavorable for the growth of myoblast cells ', Cellular Physiology and Biochemistry, vol. 54, no. 6, pp. 1177-1198 . https://doi.org/10.33594/000000308
BACKGROUND/AIMS: Compelling evidence indicates that CK2α, which is one of the two catalytic isoforms of protein kinase CK2, is required for cell viability and plays an important role in cell proliferation and differentiation. While much is known on
Autor:
Harald Schuhwerk, Annemarie Schwab, Ozge Saatci, Ozgur Sahin, Ida Rapa, Paolo Bironzo, Vignesh Ramesh, Paolo Ceppi, Marco Volante, Beatrice Parma, Ramakrishnan Natesan, Paradesi Naidu Gollavilli, Maria Eleni Vazakidou, Mohammad Aarif Siddiqui, Irfan A. Asangani
Publikováno v:
British Journal of Cancer
Siddiqui, M A, Gollavilli, P N, Ramesh, V, Parma, B, Schwab, A, Vazakidou, M E, Natesan, R, Saatci, O, Rapa, I, Bironzo, P, Schuhwerk, H, Asangani, I A, Sahin, O, Volante, M & Ceppi, P 2021, ' Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer ', British Journal of Cancer, vol. 124, pp. 281-289 . https://doi.org/10.1038/s41416-020-01095-x
Siddiqui, M A, Gollavilli, P N, Ramesh, V, Parma, B, Schwab, A, Vazakidou, M E, Natesan, R, Saatci, O, Rapa, I, Bironzo, P, Schuhwerk, H, Asangani, I A, Sahin, O, Volante, M & Ceppi, P 2021, ' Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer ', British Journal of Cancer, vol. 124, pp. 281-289 . https://doi.org/10.1038/s41416-020-01095-x
BackgroundEpithelial-to-mesenchymal transition (EMT) enhances motility, stemness and chemoresistance of carcinomas and is an important determinant of metastasis. Little is known about how various pathways coordinate to elicit EMT’s different functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d929594b980bf4391d950e24b47bc774
https://doi.org/10.1101/2020.08.13.249581
https://doi.org/10.1101/2020.08.13.249581