Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mohammad A.M. Momin"'
Autor:
Connor Howe, Mohammad A.M. Momin, Karl Bass, Ghali Aladwani, Serena Bonasera, Michael Hindle, Philip Worth Longest
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 35:196-211
Autor:
Mohammad A.M. Momin, Serena Bonasera, Michael Hindle, P. Worth Longest, Dale Farkas, Connor Howe
Publikováno v:
Pharm Res
PURPOSE: In order to improve the delivery of dry powder aerosol formulations to the lungs of infants, this study implemented an infant air-jet platform and explored the effects of different air sources, flow rates, and pulmonary mechanics on aerosoli
Excipient Enhanced Growth Aerosol Surfactant Replacement Therapy in an In Vivo Rat Lung Injury Model
Autor:
P. Worth Longest, Michael Hindle, Sahil R Chindal, Michael S. Valentine, Franck J. Kamga Gninzeko, Sneha Dhapare, Amr Hassan, Susan Boc, Dale Farkas, Rebecca L. Heise, Cindy K. Tho, Mohammad A.M. Momin
Publikováno v:
J Aerosol Med Pulm Drug Deliv
Background: In neonatal respiratory distress syndrome, breathing support and surfactant therapy are commonly used to enable the alveoli to expand. Surfactants are typically delivered through liquid instillation. However, liquid instillation does not
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1254, p 1254 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1254, p 1254 (2021)
Roflumilast is currently administered orally to control acute exacerbations in chronic obstructive pulmonary disease (COPD). However, side effects such as gastrointestinal disturbance and weight loss have limited its application. This work aimed to d
Publikováno v:
Advanced Powder Technology. 30:2473-2482
The purpose of this study was to develop an inhalable combination dry powder formulation of bedaquiline and pyrazinamide and study their physicochemical properties and safety since this combination acts synergistically against Mycobacterium tuberculo
Publikováno v:
AAPS PharmSciTech
Efficient delivery of dry powder aerosols dispersed with low volumes of air is challenging. This study aims to develop an efficient dry powder inhaler (DPI) capable of delivering spray-dried Survanta-EEG powders (3-10 mg) with a low volume (3 mL) of
Publikováno v:
AAPS PharmSciTech
This study aimed to develop and characterize a spray-dried powder aerosol formulation of a commercially available surfactant formulation, Survanta(®) intratracheal suspension, using the excipient enhanced growth (EEG) approach. Survanta EEG powders
Publikováno v:
International Journal of Pharmaceutics. 550:398-417
Tuberculosis (TB) is a major global health burden. The emergence of the human immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB control. Pulmonary delivery of drugs using dry powder inhalers (DPI) is an emerging appr
Autor:
Shubhra Sinha, C. S. Doyle, John A. Denman, Ian G. Tucker, Mohammad A.M. Momin, Shyamal C. Das
Publikováno v:
International Journal of Pharmaceutics. 541:26-36
High dose delivery of drugs to the lung using a dry powder inhaler (DPI) is an emerging approach to combat drug-resistant local infections. To achieve this, highly aerosolizable powders are required. We hypothesized that co-spray-drying kanamycin, a
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 41:415-421
A reversed phase high performance liquid chromatography (RP-HPLC) method for the simultaneous quantification of bedaquiline (TMC207), moxifloxacin and pyrazinamide in a pharmaceutical powder formulation for inhalation has been developed and validated