Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Mohammad A, Ghatei"'
Autor:
Lucy Brooks, Alexander Viardot, Anastasia Tsakmaki, Emilie Stolarczyk, Jane K. Howard, Patrice D. Cani, Amandine Everard, Michelle L. Sleeth, Arianna Psichas, Jelena Anastasovskaj, Jimmy D. Bell, Kim Bell-Anderson, Charles R. Mackay, Mohammad A. Ghatei, Stephen R. Bloom, Gary Frost, Gavin A. Bewick
Publikováno v:
Molecular Metabolism, Vol 6, Iss 1, Pp 48-60 (2017)
Objective: Dietary supplementation with fermentable carbohydrate protects against body weight gain. Fermentation by the resident gut microbiota produces short-chain fatty acids, which act at free fatty acid receptor 2 (FFAR2). Our aim was to test the
Externí odkaz:
https://doaj.org/article/6e138d5bb03648ce81d279034f1eb881
Publikováno v:
Jundishapur Journal of Microbiology. 14
Background: Uropathogenic Escherichia coli (UPEC) strains encoding superficial and secretory virulence factors leads to colonization and facilitation of bacterial growth in the host urinary tract, causing urinary tract infection (UTIs). Objectives: T
Autor:
Katalin Skrapits, Beáta Á Borsay, László Herczeg, Philippe Ciofi, Stephen R Bloom, Mohammad A Ghatei, Waljit S Dhillo, Zsolt Liposits, Erik Hrabovszky
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103977 (2014)
Kisspeptin (KP)- and neurokinin B (NKB)- synthesizing neurons of the hypothalamic arcuate nucleus play a pivotal role in the regulation of pulsatile gonadotropin-releasing hormone (GnRH) secretion. Unlike in rodents and sheep, the homologous KP and N
Externí odkaz:
https://doaj.org/article/86fff0829ce74c7ca53bd69640d490cf
Autor:
Erik Hrabovszky, Beáta Á Borsay, Kálmán Rácz, László Herczeg, Philippe Ciofi, Stephen R Bloom, Mohammad A Ghatei, Waljit S Dhillo, Zsolt Liposits
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72369 (2013)
Neurons synthesizing neurokinin B (NKB) and kisspeptin (KP) in the hypothalamic arcuate nucleus represent important upstream regulators of pulsatile gonadotropin-releasing hormone (GnRH) neurosecretion. In search of neuropeptides co-expressed in anal
Externí odkaz:
https://doaj.org/article/473b5db447464acb8b82dad3555863f7
Autor:
Erik eHrabovszky, Csilla S. Molnar, Mate eSipos, Barbara eVida, Philippe eCiofi, Beata Agnes Borsay, Laszlo eSarkadi, Laszlo eHerczeg, Stephen R. Bloom, Mohammad A. Ghatei, Waljit S. Dhillo, Imre eKallo, Zsolt eLiposits
Publikováno v:
Frontiers in Endocrinology, Vol 2 (2011)
The secretory output of gonadotropin-releasing hormone (GnRH) neurons is critically influenced by peptidergic neurons synthesizing kisspeptins (KP) and neurokinin B (NKB) in the hypothalamic infundibular nucleus (Inf). These cells mediate negative fe
Externí odkaz:
https://doaj.org/article/2a371c2191ac4d1aace4e450bc3725bb
Publikováno v:
Journal of Obesity, Vol 2011 (2011)
Endocannabinoid antagonism as a treatment for obesity and the metabolic syndrome became a hugely anticipated area of pharmacology at the start of the century. The CB1 receptor antagonist Rimonabant entered the European mass market on the back of seve
Externí odkaz:
https://doaj.org/article/fd1c393f894b4564b5eb27ae2753773a
Autor:
Julie Bakker, Stephen R. Bloom, Dick F. Swaab, Mélanie Taziaux, Annemieke S. Staphorsius, Mohammad A. Ghatei
Publikováno v:
The Journal of clinical endocrinology and metabolism, 101(6), 2380-9. The Endocrine Society
Context: Since the discovery of its central role in reproduction, our functional neuroanatomical knowledge of the hypothalamic kisspeptin system is predominantly based on animal studies. Although sex differences in kisspeptin expression have been sho
Autor:
Alexander N Comninos, Channa N. Jayasena, Shengyun Li, Minghan Hu, Mohammad A. Ghatei, Paul M. Matthews, Jelena Anastasovska, Jimmy D. Bell, Kevin T. O'Byrne, Xiao Feng Li, Meliz Sahuri-Arisoylu, Waljit S. Dhillo, Stephen R. Bloom
Publikováno v:
Brain Structure & Function
Comninos, A N, Anastasovska, J, Sahuri-Arisoylu, M, Li, X F, Li, S, Hu, M, Jayasena, C N, Ghatei, M A, Bloom, S R, Matthews, P M, O'Byrne, K T, Bell, J D & Dhillo, W S 2016, ' Kisspeptin signaling in the amygdala modulates reproductive hormone secretion ', Brain structure & function, vol. 221, no. 4, pp. 2035-47 . https://doi.org/10.1007/s00429-015-1024-9
Comninos, A N, Anastasovska, J, Sahuri-Arisoylu, M, Li, X F, Li, S, Hu, M, Jayasena, C N, Ghatei, M A, Bloom, S R, Matthews, P M, O'Byrne, K T, Bell, J D & Dhillo, W S 2016, ' Kisspeptin signaling in the amygdala modulates reproductive hormone secretion ', Brain structure & function, vol. 221, no. 4, pp. 2035-47 . https://doi.org/10.1007/s00429-015-1024-9
Kisspeptin (encoded by KISS1) is a crucial activator of reproductive function. The role of kisspeptin has been studied extensively within the hypothalamus but little is known about its significance in other areas of the brain. KISS1 and its cognate r
Autor:
Neil E. Hill, Christian Ardley, Joanne L. Fallowfield, Gary Frost, Duncan R. Wilson, Kevin Murphy, Mike Stacey, Mohammad A. Ghatei, Stephen R. Bloom, Simon K. Delves, Stephen J. Brett
Publikováno v:
Obesity. 23:608-614
OBJECTIVE: Understanding the mechanisms that drive weight loss in a lean population may elucidate systems that regulate normal energy homeostasis. This prospective study of British military volunteers investigated the effects of a 6-month deployment
Autor:
Ian F. Godsland, Ali Alsafi, Rachel C. Troke, Victoria Salem, Mandy Donaldson, Mohammad A. Ghatei, Kevin C.R. Baynes, James Minnion, Benjamin C. T. Field, Stephen R. Bloom, Tricia Tan, Akila De Silva, Shivani Misra
Publikováno v:
E2324
E2317
The Journal of Clinical Endocrinology and Metabolism
E2317
The Journal of Clinical Endocrinology and Metabolism
Context: The combination of peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) has been proposed as a potential treatment for diabetes and obesity. However, the combined effects of these hormones, PYY3–36 and GLP-17–36 amide, on glucose homeost