Zobrazeno 1 - 10
of 10
pro vyhledávání: '"MohamedHusen Munshi"'
Autor:
Iart Luca Shytaj, Francesco Andrea Procopio, Mohammad Tarek, Irene Carlon‐Andres, Hsin‐Yao Tang, Aaron R Goldman, MohamedHusen Munshi, Virender Kumar Pal, Mattia Forcato, Sheetal Sreeram, Konstantin Leskov, Fengchun Ye, Bojana Lucic, Nicolly Cruz, Lishomwa C Ndhlovu, Silvio Bicciato, Sergi Padilla‐Parra, Ricardo Sobhie Diaz, Amit Singh, Marina Lusic, Jonathan Karn, David Alvarez‐Carbonell, Andrea Savarino
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp 1-20 (2021)
Abstract HIV‐1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a determinant of susceptibility to HIV‐1 infection, but i
Externí odkaz:
https://doaj.org/article/c1e843aa09bd42f190c50b143e7746de
Autor:
Shalini Singh, Sourav Ghosh, Virender Kumar Pal, MohamedHusen Munshi, Pooja Shekar, Diwakar Tumkur Narasimha Murthy, Govindasamy Mugesh, Amit Singh
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 5, Pp 1-19 (2021)
Abstract Reactive oxygen species (ROS) regulates the replication of human immunodeficiency virus (HIV‐1) during infection. However, the application of this knowledge to develop therapeutic strategies remained unsuccessful due to the harmful consequ
Externí odkaz:
https://doaj.org/article/f2a2996258c1481ca509ccfa645b570c
Autor:
Ryan C. Burdick, Vinay K. Pathak, Wei-Shau Hu, MohamedHusen Munshi, Jonathan M. O. Rawson, Chenglei Li, Kunio Nagashima
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance For several decades, retroviral core uncoating has been thought to occur in the cytoplasm in coordination with reverse transcription, and while some recent studies have concluded that HIV-1 uncoating occurs at the nuclear envelope during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ce1f643596cb110f3c63162df7f69f
http://europepmc.org/articles/PMC7071919
http://europepmc.org/articles/PMC7071919
Autor:
Govindasamy Mugesh, Diwakar Tumkur Narasimha Murthy, Amit Singh, Virender Kumar Pal, MohamedHusen Munshi, Sourav Ghosh, Shalini Singh, Pooja Shekar
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 5, Pp n/a-n/a (2021)
EMBO Molecular Medicine, Vol 13, Iss 5, Pp n/a-n/a (2021)
Reactive oxygen species (ROS) regulates the replication of human immunodeficiency virus (HIV‐1) during infection. However, the application of this knowledge to develop therapeutic strategies remained unsuccessful due to the harmful consequences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c156de64c638070dfefa160b85e01efb
http://europepmc.org/articles/PMC8103102
http://europepmc.org/articles/PMC8103102
Autor:
Aaron R. Goldman, Fengchun Ye, Andrea Savarino, Konstantin Leskov, Iart Luca Shytaj, Mattia Forcato, David Alvarez-Carbonell, Bojana Lucic, Irene Carlon-Andres, Amit Singh, Marina Lusic, Ricardo Sobhie Diaz, Silvio Bicciato, MohamedHusen Munshi, Nicolly Cruz, Mohammad Tarek, Hsin-Yao Tang, Francesco A. Procopio, Sergi Padilla-Parra
HIV-1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a determinant of susceptibility to HIV-1 infection, but its role in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242cb63dffab6cb78b5ef9e697b8caee
https://doi.org/10.1101/2020.12.30.424810
https://doi.org/10.1101/2020.12.30.424810
Autor:
Govindasamy Mugesh, R. S. Rajmani, Virender Kumar Pal, MohamedHusen Munshi, Amit Singh, Sourav Ghosh, Shalini Singh
Reactive oxygen species (ROS) regulates the proliferation of human immunodeficiency virus (HIV-1) and Mycobacterium tuberculosis (Mtb) inside the infected immune cells. However, the application of this knowledge to develop therapeutic strategies rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c811013bf93c50e40f58778f4af349f
https://doi.org/10.1101/2020.08.15.252098
https://doi.org/10.1101/2020.08.15.252098
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis
Autor:
Vijaykamal Ahuja, Amit Singh, Mansi Mehta, R. S. Rajmani, Parijat Bandyopadhyay, Richa Mishra, Radha Shandil, MohamedHusen Munshi, Vasista Adiga, Sakshi Kohli, Nitish Malhotra, Aswin Sai Narain Seshasayee
Publikováno v:
Sci Transl Med
The capacity of Mycobacterium tuberculosis (Mtb) to tolerate multiple antibiotics represents a major problem in tuberculosis (TB) management. Heterogeneity in Mtb populations is one of the factors that drives antibiotic tolerance during infection. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd68e0a987d5f8e2ab4544045fbf5e0f
https://europepmc.org/articles/PMC7212044/
https://europepmc.org/articles/PMC7212044/
Autor:
Amit Singh, Abhilash Mohan, Chandrani Thakur, Kushi Anand, Jyothi Padiadpu, Priyanka Baloni, Nagasuma Chandra, MohamedHusen Munshi
Publikováno v:
ACS Infectious Diseases. 2:592-607
The global mechanisms and associated molecular alterations that occur in drug-resistant mycobacteria are poorly understood. To address this, we obtain genomics data and then construct a genome-scale response network in isoniazid-resistant Mycobacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64108e8c7f8f0e07d7eaa9945530537
https://doi.org/10.1021/acsinfecdis.6b00004
https://doi.org/10.1021/acsinfecdis.6b00004
Autor:
Shahid Jameel, MohamedHusen Munshi, Sohrab Khan, Ashima Bhaskar, Sadaf Fatima, Amit Singh, Rahul Arya
Publikováno v:
The Journal of Biological Chemistry
Background: Abnormal glutathione poise has been associated with HIV-1 infection; however, the underlying importance is unclear. Results: Measurement of glutathione-redox potential (EGSH) revealed higher capacity of latently infected cells to resist o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103999f8796f0d52f5c7e9889391c86a
https://igi.indrastra.com/items/show/190157
https://igi.indrastra.com/items/show/190157
Autor:
Mansi Mehta, Kevin Redding, Nimi Vashi, Manbeena Chawla, Pankti Parikh, Anup Srivastava, Amit Singh, Adrie J. C. Steyn, Dhiraj Kumar, MohamedHusen Munshi, K. V. Narasimhulu, Alka Saxena, Deborah Mai
Publikováno v:
Molecular Microbiology
Host-generated oxidative stress is considered one of the main mechanisms constraining Mycobacterium tuberculosis (Mtb) growth. The redox-sensing mechanisms in Mtb are not completely understood. Here we show that WhiB4 responds to oxygen (O2) and nitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3687372f830590bb6983419cff7223a5
https://pubmed.ncbi.nlm.nih.gov/22780904
https://pubmed.ncbi.nlm.nih.gov/22780904