Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Mohamed Z, Gad"'
Autor:
Alyaa Dawoud, Rana A. Youness, Kareem Elsayed, Heba Nafae, Hoda Allam, Hager Adel Saad, Carole Bourquin, Csaba Szabo, Reham Abdel-Kader, Mohamed Z. Gad
Publikováno v:
Redox Report, Vol 29, Iss 1 (2024)
Gasotransmitters play crucial roles in regulating many physiological processes, including cell signaling, cellular proliferation, angiogenesis, mitochondrial function, antioxidant production, nervous system functions and immune responses. Hydrogen su
Externí odkaz:
https://doaj.org/article/80ba841df7354ce5806657a1c6a6fb21
Autor:
Alyaa Dawoud, Rana A. Youness, Heba Nafea, Tamer Manie, Carole Bourquin, Csaba Szabo, Reham M. Abdel-Kader, Mohamed Z. Gad
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC). Cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE), and 3-
Externí odkaz:
https://doaj.org/article/4d093e2dbc304a5a9126e4cd65249f52
Autor:
Heba Nafea, Rana A. Youness, Alyaa Dawoud, Nour Khater, Tamer Manie, Reham Abdel-Kader, Carole Bourquin, Csaba Szabo, Mohamed Z. Gad
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e21063- (2023)
Introduction: Hydrogen sulfide (H2S) has been recently scrutinized for its critical role in aggravating breast cancer (BC) tumorigenicity. Several cancers aberrantly express H2S synthesizing enzymes; Cystathionine-β-synthase (CBS) and cystathionine-
Externí odkaz:
https://doaj.org/article/f0c83e05459b42a9abe929163a168cb5
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract N6-methyl-adenosine (m6A) is the most prevalent modification on mRNAs and long noncoding RNAs (lnRNAs) in higher eukaryotes. Modulation of m6A relies on m6A writers, erasers and readers. m6A modification contributes to diverse fundamental bi
Externí odkaz:
https://doaj.org/article/1e867e9c4a0f4a868c688ddb2c2827df
Autor:
Rana A. Youness, Danira Ashraf Habashy, Nour Khater, Kareem Elsayed, Alyaa Dawoud, Sousanna Hakim, Heba Nafea, Carole Bourquin, Reham M. Abdel-Kader, Mohamed Z. Gad
Publikováno v:
Non-Coding RNA, Vol 10, Iss 1, p 7 (2024)
Recently, myriad studies have defined the versatile abilities of gasotransmitters and their synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non-oncological circuits and, thus, nominated them as possible ther
Externí odkaz:
https://doaj.org/article/8ed9621647dd4bb49fa74bb5764a0756
Autor:
Mohamed A. Farag, Mohamed Z. Gad
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Omega-9 fatty acids represent one of the main mono-unsaturated fatty acids (MUFA) found in plant and animal sources. They are synthesized endogenously in humans, though not fully compensating all body requirements. Consequently, t
Externí odkaz:
https://doaj.org/article/1e8ba8b36d3b4fc8a0a59729ab0deb09
Publikováno v:
Non-coding RNA Research, Vol 6, Iss 4, Pp 174-186 (2021)
Long non-coding RNAs (LncRNAs) play a vital role in the process of malignant transformation. In breast cancer (BC), lncRNAs field is currently under intensive investigations. Yet, the role of lncRNAs as promising diagnostic and/or prognostic biomarke
Externí odkaz:
https://doaj.org/article/668b632131db412d8b68d661cb8e1c7e
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Background Cardiovascular disease (CVD) remains the major cause of death worldwide. Most CVD can be prevented by addressing risk factors. Acute myocardial infarction (AMI) is an inflammatory disorder characterized by changes in several cytok
Externí odkaz:
https://doaj.org/article/9b5bf10b639347309600e9ab0d0a3196
Publikováno v:
Journal of Advanced Research, Vol 27, Iss , Pp 1-10 (2021)
Introduction: Hydrogen sulphide (H2S) is one of the gasotransmitters that was reported to have a cardioprotective effect at its physiological levels in blood. Previous determinations of H2S levels in cardiovascular disease (CVD) patients suffered fro
Externí odkaz:
https://doaj.org/article/efcbc16443f54067a3c263df910f9895
Autor:
Sidneia Sousa Santos, Larissa de Oliveira Cavalcanti Peres Rodrigues, Vanessa Martins, Maria Petrosino, Karim Zuhra, Kelly Ascenção, Abhishek Anand, Reham Mahmoud Abdel-Kader, Mohamed Z. Gad, Carole Bourquin, Csaba Szabo
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 647 (2023)
Cystathionine β-synthase (CBS), CSE (cystathionine γ-lyase) and 3-mercaptopyruvate sulfurtransferase (3-MST) have emerged as three significant sources of hydrogen sulfide (H2S) in various forms of mammalian cancer. Here, we investigated the functio
Externí odkaz:
https://doaj.org/article/3415f81c337d409ea93fdfac71801fc6