Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mohamed Y. Siraj"'
Publikováno v:
Journal of food protection. 41(5)
To study the interference by mycotoxins in protein measurements, solutions of various concentrations of aflatoxin B1, citrinin, cytochalasin B, ochratoxin A, patulin, penicillic acid, rubratoxins A and B, T-2 toxin and zearalenone were tested for a p
Publikováno v:
Food and Cosmetics Toxicology. 18:261-266
The effects of aflatoxin B 1 and/or rubratoxin B on hepatic monooxygenase and hepatic, brain and renal ATPase activities were examined in neonatal rats exposed to a single treatment of one or both toxins. Animals received orally 0·4 mg aflatoxin B 1
Publikováno v:
Experimental and Molecular Pathology. 34:94-109
Rubratoxin B, the principal toxin produced by Penicillium rubrum , causes hepatic damage. The present study describes ultrastructural changes in rat livers at intervals of 3, 6, 24, and 72 hr following administration of 0.36 mg/kg rubratoxin B. Three
Publikováno v:
Toxicology and Applied Pharmacology. 73:195-203
The pharmacokinetics of penicillic acid (PA), a carcinogenic mycotoxin, was investigated in male mice. Absorption of PA after po administration of [14C]PA was rapid. Only a small percentage of the radioactivity in the plasma was unchanged PA. After i
Autor:
Mohamed Y. Siraj, A. Wallace Hayes
Publikováno v:
Toxicology. 17:17-28
Alterations in the hepatic microsomal monooxygenase system and in the concentrations of rubratoxin B in urine and feces were examined in male mice pretreated with corn oil, phenobarbital or 3-methylcholanthrene (3MC) and then given a single i.p. dose
Publikováno v:
Journal of AOAC INTERNATIONAL. 61:601-604
Using ultraviolet absorption spectrometry, rubratoxin B can be quantitatively determined over the concentration range 1.0 × 10−3 to 3.8 × 10×5M in acetonitrile or p-dioxane. Fluorescence, while observable, is a practical method only with apparat
Autor:
Mohamed Y. Siraj, A. Wallace Hayes
Publikováno v:
Toxicology and Applied Pharmacology. 48:351-359
The in vivo effects of rubratoxin B on hepatic mixed-function oxidase enzymes in male mice were examined. Animals were exposed to a single ip dose of 0.25, 0.5, 1.0, or 1.5 mg rubratoxin B/kg or daily doses of 0.5 mg/kg rubratoxin B for 14 days. Rubr
Publikováno v:
Food and cosmetics toxicology. 17(2)
The metabolism of rubratoxin B was studied in vitro using rat hepatic subcellular fractions. Primarily, metabolism of rubratoxin B involved a non-enzymatic process in the microsomal supernatant fluid. The transformation products were mainly water-sol
Publikováno v:
Journal of toxicology and environmental health. 8(1-2)
The effects of citrinin, ochratoxin A, or a combination of the two mycotoxins on the hepatic monooxygenase system and on hepatic and renal adenosinetriphosphatase (A TPase) activities were examined in neonatal rats exposed to a single treatment of on