Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mohamed X, Ibrahim"'
Autor:
Mohamed X. Ibrahim, Martin O. Bergo
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1292-1294 (2021)
Externí odkaz:
https://doaj.org/article/7e7578a08c4f4bd08e4d47803e97d077
Autor:
Murali K. Akula, Mohamed X. Ibrahim, Emil G. Ivarsson, Omar M. Khan, Israiel T. Kumar, Malin Erlandsson, Christin Karlsson, Xiufeng Xu, Mikael Brisslert, Cord Brakebusch, Donghai Wang, Maria Bokarewa, Volkan I. Sayin, Martin O. Bergo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Macrophage specific deletion of GGTase-I, a prenylation enzyme, in mice induces inflammatory response and rheumatoid arthritis. Here the authors show that GGTase-I deficiency and the resulting reduction of RAC1 prenylation increase RAC1 interaction w
Externí odkaz:
https://doaj.org/article/64e45db836524099a563e469b049824a
Autor:
Xue Chen, Haidong Yao, Muhammad Kashif, Gwladys Revêchon, Maria Eriksson, Jianjiang Hu, Ting Wang, Yiran Liu, Elin Tüksammel, Staffan Strömblad, Ian M Ahearn, Mark R Philips, Clotilde Wiel, Mohamed X Ibrahim, Martin O Bergo
Publikováno v:
eLife, Vol 10 (2021)
A farnesylated and methylated form of prelamin A called progerin causes Hutchinson-Gilford progeria syndrome (HGPS). Inhibiting progerin methylation by inactivating the isoprenylcysteine carboxylmethyltransferase (ICMT) gene stimulates proliferation
Externí odkaz:
https://doaj.org/article/af9f4ea451d04c5cba3ce05449cb18c3
Autor:
Zhiyuan V. Zou, Kristell Le Gal, Ahmed E. El Zowalaty, Lara E. Pehlivanoglu, Viktor Garellick, Nadia Gul, Mohamed X. Ibrahim, Per-Olof Bergh, Marcus Henricsson, Clotilde Wiel, Levent M. Akyürek, Martin O. Bergo, Volkan I. Sayin, Per Lindahl
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 241 (2021)
Dietary antioxidants and supplements are widely used to protect against cancer, even though it is now clear that antioxidants can promote tumor progression by helping cancer cells to overcome barriers of oxidative stress. Although recent studies have
Externí odkaz:
https://doaj.org/article/080aefb9e0cd473fb29d3da2d5029ec5
Autor:
Kristell Le Gal, Clotilde Wiel, Mohamed X. Ibrahim, Marcus Henricsson, Volkan I. Sayin, Martin O. Bergo
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 163 (2021)
Cancer cells produce high levels of mitochondria-associated reactive oxygen species (ROS) that can damage macromolecules, but also promote cell signaling and proliferation. Therefore, mitochondria-targeted antioxidants have been suggested to be usefu
Externí odkaz:
https://doaj.org/article/78b032b081434a858965530fd6f66556
Autor:
Mohamed X. Ibrahim, Anna Staffas, Volkan I. Sayin, Per Lindahl, Christin Karlsson, Murali K. Akula, Martin O. Bergo, Jaroslaw Cisowski
Publikováno v:
Leukemia. 35:606-609
Autor:
Donghai Wang, Malin C. Erlandsson, Mohamed X. Ibrahim, Israiel T. Kumar, Christin Karlsson, Cord Brakebusch, Xiufeng Xu, Volkan I. Sayin, Maria Bokarewa, Omar M. Khan, Emil G. Ivarsson, Martin O. Bergo, Murali K. Akula, Mikael Brisslert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Akula, M K, Ibrahim, M X, Ivarsson, E G, Khan, O M, Kumar, I T, Erlandsson, M, Karlsson, C, Xu, X, Brisslert, M, Brakebusch, C, Wang, D, Bokarewa, M, Sayin, V I & Bergo, M O 2019, ' Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions ', Nature Communications, vol. 10, no. 1, 3975, pp. 1-13 . https://doi.org/10.1038/s41467-019-11606-x
Nature Communications
Akula, M K, Ibrahim, M X, Ivarsson, E G, Khan, O M, Kumar, I T, Erlandsson, M, Karlsson, C, Xu, X, Brisslert, M, Brakebusch, C, Wang, D, Bokarewa, M, Sayin, V I & Bergo, M O 2019, ' Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions ', Nature Communications, vol. 10, no. 1, 3975, pp. 1-13 . https://doi.org/10.1038/s41467-019-11606-x
Rho family proteins are prenylated by geranylgeranyltransferase type I (GGTase-I), which normally target proteins to membranes for GTP-loading. However, conditional deletion of GGTase-I in mouse macrophages increases GTP-loading of Rho proteins, lead
Autor:
Jianjiang Hu, Maria Eriksson, Clotilde Wiel, Ian M. Ahearn, Ting Wang, Staffan Strömblad, Martin O. Bergo, Elin Tüksammel, Muhammad Kashif, Mohamed X. Ibrahim, Mark R. Philips, Haidong Yao, Gwladys Revêchon, Yiran Liu, Xue Chen
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
A farnesylated and methylated form of prelamin A called progerin causes Hutchinson-Gilford progeria syndrome (HGPS). Inhibiting progerin methylation by inactivating the isoprenylcysteine carboxylmethyltransferase (ICMT) gene stimulates proliferation
Autor:
Per Lindahl, Martin O. Bergo, Zhiyuan V. Zou, Lara E. Pehlivanoglu, Clotilde Wiel, Levent M. Akyürek, Volkan I. Sayin, Mohamed X. Ibrahim, Per-Olof Bergh, Marcus Henricsson, Nadia Gul, Ahmed E. El Zowalaty, Kristell Le Gal, Viktor Garellick
Publikováno v:
Antioxidants, Vol 10, Iss 241, p 241 (2021)
Antioxidants
Volume 10
Issue 2
Antioxidants
Volume 10
Issue 2
Dietary antioxidants and supplements are widely used to protect against cancer, even though it is now clear that antioxidants can promote tumor progression by helping cancer cells to overcome barriers of oxidative stress. Although recent studies have
Autor:
Elin Tüksammel, Clotilde Wiel, Mark R. Philips, Ting Wang, Mohamed X. Ibrahim, Haidong Yao, Staffan Strömblad, Gwladys Revêchon, Muhammad Kashif, Jianjiang Hu, Maria Eriksson, Ian M. Ahearn, Yiran Liu, Martin O. Bergo, Xue Chen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8714222d18d7b1841bfe7780f20f834
https://doi.org/10.7554/elife.63284.sa2
https://doi.org/10.7554/elife.63284.sa2