Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Mohamed W Attwa"'
Autor:
Abdullah Al-Dhfyan, Ayodele Alaiya, Falah Al-Mohanna, Mohamed W Attwa, Abdullah F AlAsmari, Saleh A Bakheet, Hesham M. Korashy
Publikováno v:
Journal of Advanced Research, Vol 50, Iss , Pp 177-192 (2023)
Introduction: Activating the aryl hydrocarbon receptor upon exposure to environmental pollutants promotes development of breast cancer stem cell (CSCs). BCL-2 family proteins protect cancer cells from the apoptotic effects of chemotherapeutic drugs.
Externí odkaz:
https://doaj.org/article/077aed138a744559b39a47fddf63d0c3
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214598 (2019)
Dacomitinib (DMB) is a second-generation irreversible tyrosine kinase inhibitor (TKI) that is claimed to overcome the disadvantages of the resistance reported for first-line epidermal growth factor receptor (EGFR) TKIs. Towards the end of 2018, the U
Externí odkaz:
https://doaj.org/article/c99039ff952d4259a13f0f1bf5d2e23c
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164967 (2016)
In the current work, a rapid, specific, sensitive and validated liquid chromatography tandem mass-spectrometric method was developed for the quantification of ponatinib (PNT) in human plasma and rat liver microsomes (RLMs) with its application to met
Externí odkaz:
https://doaj.org/article/3c55048d83584519b8d43623e8c2d6bc
Autor:
Ziyad Binkhathlan, Raisuddin Ali, Osman Yusuf, Abdullah H. Alomrani, Mohamed M. Badran, Abdullah K. Alshememry, Aws Alshamsan, Faleh Alqahtani, Wajhul Qamar, Mohamed W. Attwa
Publikováno v:
Polymers, Vol 16, Iss 15, p 2232 (2024)
This study aimed to investigate the potential of polycaprolactone–vitamin E TPGS (PCL-TPGS) micelles as a delivery system for oral administration of paclitaxel (PTX). The PCL-TPGS copolymer was synthesized using ring opening polymerization, and PTX
Externí odkaz:
https://doaj.org/article/7a0a361e661e42d7a7e1cfefe3a8e486
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Simvastatin (SV) is a hypolipidemic agent, and it is the 2nd most widely prescribed lipid-lowering drug. Here, the detection and characterization of SV and its metabolites was studied in selected organs/tissues (lung, liver, brain, heart and
Externí odkaz:
https://doaj.org/article/78526b5b10b64e80b6a158b6a516cb9c
Autor:
Ibrahim A. Darwish, Nourah Z. Alzoman, Aliyah Almomen, Abdulrahman A. Almehizia, Mohamed W. Attwa, Hany W. Darwish, Ahmed Y. Sayed
Publikováno v:
RSC Advances. 13:7929-7938
Duvelisib (DUV) is a new oral phosphoinositide-3-kinase (PI3K)-δ and PI3K-γ inhibitor.
Publikováno v:
Crystals; Volume 13; Issue 7; Pages: 1020
This study investigates the crystal structure, physicochemical properties, and pharmacokinetic profile of Ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (EAMT) as a potential therapeutic agent. The crystal structure was
Publikováno v:
Polymers; Volume 15; Issue 13; Pages: 2808
Supramolecular fexofenadine sensors have been constructed. Although noncovalent intermolecular and intramolecular interactions, which are far weaker than covalent contacts, are the main focus of supramolecular chemistry, they can be used to create se
Publikováno v:
Separations; Volume 10; Issue 6; Pages: 330
Tepotinib (MSC2156119) is a potent mesenchymal–epithelial transition (MET) factor inhibitor, a receptor tyrosine kinase that plays a crucial role in promoting cancer cell malignant progression. Adverse effects of tepotinib (TEP), such as peripheral
Publikováno v:
Molecules; Volume 28; Issue 10; Pages: 4225
Fenebrutinib is an orally available Bruton tyrosine kinase inhibitor. It is currently in multiple phase III clinical trials for the management of B-cell tumors and autoimmune disorders. Elementary in-silico studies were first performed to predict sus