Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mohamed Slaoui"'
Autor:
David Balayssac, Jérôme Busserolles, Catherine Broto, Cristelle Dalbos, Laetitia Prival, Sylvain Lamoine, Damien Richard, Mercedes Quintana, Aurélia Herbet, Sandrine Hilairet, Yang Hu, Irena Loryan, Warren E. Glaab, Laura Micheli, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Olivier Perrault, Mohamed Slaoui
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115535- (2023)
Identifying compounds that are neurotoxic either toward the central or the peripheral nervous systems (CNS or PNS) would greatly benefit early stages of drug development by derisking liabilities and selecting safe compounds. Unfortunately, so far ass
Externí odkaz:
https://doaj.org/article/efd0b2fddcb7403794d7295e4d4dd042
Autor:
Laurent Pradier, Véronique Blanchard-Brégeon, Andrees Bohme, Thomas Debeir, Jean Menager, Patrick Benoit, Pascal Barneoud, Véronique Taupin, Philippe Bertrand, Philippe Dugay, Béatrice Cameron, Yi Shi, Souad Naimi, Marc Duchesne, Marie Gagnaire, Tim Weeden, Tara Travaline, David Reczek, Leonard Khiroug, Mohamed Slaoui, Pascale Brunel, Hidehiro Fukuyama, Jeffrey Ravetch, Thierry Canton, Caroline Cohen
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-23 (2018)
Abstract Background Anti-amyloid β (Aβ) immunotherapy represents a major area of drug development for Alzheimer’s disease (AD). However, Aβ peptide adopts multiple conformations and the pathological forms to be specifically targeted have not bee
Externí odkaz:
https://doaj.org/article/8e1251be3bb94110879a8c1cd6a6d727
Autor:
Xiaobing Zhou, Isabelle Guizon, Bo Li, Yaligara Veeranagouda, Tianyi Zhang, Mohamed Slaoui, Philippe Detilleux, Zhe Qu, Jufeng Wang, Yang Yang, Thierry Gury, Oliver Poetz, Jean-Charles Gautier, Bart H.J. van den Berg, Xavier Palazzi, Thomas O. Joos, Jean-François Léonard, Aziz Filali-Ansary, Eric Boitier
Publikováno v:
Toxicology and Applied Pharmacology. 303:1-10
Most studies to evaluate kidney safety biomarkers have been performed in rats. This study was conducted in Cynomolgus monkeys in order to evaluate the potential usefulness of novel biomarkers of nephrotoxicity in this species. Groups of 3 males were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3139e50ff5d0659eefc47ab57bd61e29
https://doi.org/10.1016/j.taap.2016.04.012
https://doi.org/10.1016/j.taap.2016.04.012
Autor:
Marie Gagnaire, Souad Naimi, Hidehiro Fukuyama, Véronique Taupin, Leonard Khiroug, Thierry Canton, Patrick Benoit, Mohamed Slaoui, Pascale Brunel, Yi Shi, Laurent Pradier, Weeden Timothy E, Tara Travaline, Beatrice Cameron, Caroline Cohen, Philippe Bertrand, Jean Menager, Thomas Debeir, Pascal Barneoud, David Reczek, Jeffrey V. Ravetch, Andrees Bohme, Véronique Blanchard-Bregeon, Marc Duchesne, Philippe Dugay
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-23 (2018)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background Anti-amyloid β (Aβ) immunotherapy represents a major area of drug development for Alzheimer’s disease (AD). However, Aβ peptide adopts multiple conformations and the pathological forms to be specifically targeted have not been identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e993b8130a9f905cbd824ac1496b5c1
https://doi.org/10.1186/s13195-018-0447-y
https://doi.org/10.1186/s13195-018-0447-y
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1641
Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ noticeable grossly changes should be recorded and critical tissue samples may be stored for the subsequent evaluation. It is therefore important that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb0117dd1802ca8484a676237c596fff
https://pubmed.ncbi.nlm.nih.gov/28748458
https://pubmed.ncbi.nlm.nih.gov/28748458
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971701
Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ noticeable grossly changes should be recorded and critical tissue samples may be stored for the subsequent evaluation. It is therefore important that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a5c1f9495ece7b8663b48f4a2bb091
https://doi.org/10.1007/978-1-4939-7172-5_3
https://doi.org/10.1007/978-1-4939-7172-5_3
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971701
Histological procedures aim at providing good-quality sections that can be used for a light microscopic evaluation of tissue. These are applicable to identify either spontaneous or diseases-induced changes. Routinely, tissues are fixed with neutral f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e160fa54f739c37a80be389c65ca9def
https://doi.org/10.1007/978-1-4939-7172-5_4
https://doi.org/10.1007/978-1-4939-7172-5_4
Publikováno v:
Toxicologic Pathology. 39:1115-1128
Kidney is a major target organ in preclinical studies. In recent years, intense research has been undertaken to characterize novel renal toxicity biomarkers. In this context, we studied nephron segment specific antibodies against aquaporin-1 (AQP-1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a20d2991cf479ba8d9abfefee72d056
https://doi.org/10.1177/0192623311425060
https://doi.org/10.1177/0192623311425060
Publikováno v:
Nature. 496:159-161
Kristoffer Famm and colleagues unveil a multidisciplinary initiative to develop medicines that use electrical impulses to modulate the body's neural circuits.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ef30de2a374d29a8a8f008792aea35
https://doi.org/10.1038/496159a
https://doi.org/10.1038/496159a
Autor:
Moncef Mohamed Slaoui, David I. Bernstein, Fernando J. Bravo, Lawrence R. Stanberry, Nigel Bourne, Myriam Francotte, Martin G. Myers
Publikováno v:
The Journal of Infectious Diseases. 187:542-549
In two recent clinical trials, a vaccine containing herpes simplex virus (HSV) type 2 glycoprotein D (gD2) and a novel adjuvant AS04 comprising alum (Al) and 3-deactylated monophosphoryl lipid A (3-dMPL) afforded HSV-seronegative women significant pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4d123e0bd63b7dd31e06b50034d138
https://doi.org/10.1086/374002
https://doi.org/10.1086/374002