Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mohamed Siyabeldin E. Ahmed"'
Autor:
Jakob Voelkl, Kousi Alzoubi, Abdel-Karim Mamar, Mohamed Siyabeldin E. Ahmed, Majed Abed, Florian Lang
Publikováno v:
Kidney & Blood Pressure Research, Vol 38, Iss 1, Pp 42-51 (2014)
Background/Aim: Anemia in renal insufficiency results in part from impaired erythrocyte formation due to erythropoietin and iron deficiency. Beyond that, renal insufficiency enhances eryptosis, the suicidal erythrocyte death characterized by phosphat
Externí odkaz:
https://doaj.org/article/1349b727556342989a85289427fc2c89
Autor:
Ioana Alesutan, Martina Feger, Tatsiana Pakladok, Sobuj Mia, Mohamed Siyabeldin E. Ahmed, Jakob Voelkl, Florian Lang
Publikováno v:
Kidney & Blood Pressure Research, Vol 37, Iss 4-5, Pp 475-487 (2013)
Background: Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney, is required for the suppression of 1,25(OH)2D3-generating 25-hydroxyvitamin D3 1-alpha-hydroxylase (Cyp27b1) by FGF23. Conversely, 1,25(OH)2D3 stimulates, b
Externí odkaz:
https://doaj.org/article/1578cafcbe754456838e019c5be08c75
Autor:
Jakob Voelkl, Venkanna Pasham, Mohamed Siyabeldin E. Ahmed, Britta Walker, Kalina Szteyn, Dietmar Kuhl, Bernhard Metzler, Ioana Alesutan, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 1, Pp 25-38 (2013)
Background/Aims: The serum- and glucocorticoid-inducible kinase Sgk1 contributes to cardiac remodeling and development of heart failure, which is paralelled by Sgk1-dependent stimulation of the cardiac Na+/H+ exchanger Nhe1. Glucocorticoids are power
Externí odkaz:
https://doaj.org/article/62d24f05e4ea4dfeba55901cf771ff29
Publikováno v:
Kidney & Blood Pressure Research, Vol 37, Iss 2-3, Pp 158-167 (2013)
Background: Anemia is a major complication of end stage renal disease. The anemia is mainly the result of impaired formation of erythrocytes due to lack of erythropoietin and iron deficiency. Compelling evidence, however, points to the contribution o
Externí odkaz:
https://doaj.org/article/4b69c02d70dc48829bb46f7c13c2fd30
Autor:
Florian Lang, Ioana Alesutan, Jakob Voelkl, Martina Feger, Tatsiana Pakladok, Mohamed Siyabeldin E. Ahmed, Sobuj Mia
Publikováno v:
Kidney & Blood Pressure Research, Vol 37, Iss 4-5, Pp 475-487 (2013)
Background: Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney, is required for the suppression of 1,25(OH)2D3-generating 25-hydroxyvitamin D3 1-alpha-hydroxylase (Cyp27b1) by FGF23. Conversely, 1,25(OH)2D3 stimulates, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9748e2e1543ea7c265319f9785aaea1f
https://doi.org/10.1159/000355728
https://doi.org/10.1159/000355728
Autor:
Mohamed Siyabeldin E. Ahmed, Shuchen Gu, Florian Lang, Balasaheb Siraskar, Evi Schmid, Jakob Völkl, Michael Föller, Christina Leibrock, Undine E. Lang, Michael Hierlmeier
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 462:811-819
Glycogen synthase kinase 3 (GSK3) plays a decisive role in the regulation of multiple functions. GSK3 is phosphorylated and its activity inhibited by protein kinase B (PKB/Akt) and serum and glucocorticoid inducible kinase (SGK) isoforms, which are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15dde6b3e5505e051d9e9718b397f56
https://doi.org/10.1007/s00424-011-1006-6
https://doi.org/10.1007/s00424-011-1006-6
Autor:
Jakob Voelkl, Kousi Alzoubi, Abdel-Karim Mamar, Mohamed Siyabeldin E. Ahmed, Majed Abed, Florian Lang
Publikováno v:
Kidney & Blood Pressure Research, Vol 38, Iss 1, Pp 42-51 (2014)
Background/Aim: Anemia in renal insufficiency results in part from impaired erythrocyte formation due to erythropoietin and iron deficiency. Beyond that, renal insufficiency enhances eryptosis, the suicidal erythrocyte death characterized by phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4397c16bfd9d8a5a9c64ad7c421d5560
https://pubmed.ncbi.nlm.nih.gov/24556698
https://pubmed.ncbi.nlm.nih.gov/24556698
Autor:
Leticia Quintanilla-Martinez, Volker Kuhn, Kevin P. Rosenblatt, Martina Feger, Florian Lang, Mohamed Siyabeldin E. Ahmed, Ioana Alesutan, Sobuj Mia, Makoto Kuro-o, Christina Leibrock, Jakob Voelkl
Klotho is a potent regulator of 1,25-hydroxyvitamin D3 [1,25(OH)2D3] formation and calcium-phosphate metabolism. Klotho-hypomorphic mice (kl/kl mice) suffer from severe growth deficits, rapid aging, hyperphosphatemia, hyperaldosteronism, and extensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9df5aadda4352ec88d6aedd16cb733
https://europepmc.org/articles/PMC3561808/
https://europepmc.org/articles/PMC3561808/
Autor:
Jakob Voelkl, Florian Lang, Martina Feger, Sobuj Mia, Bernhard Metzler, Shuchen Gu, Yun Lin, Mohamed Siyabeldin E. Ahmed, Ambrish Saxena, Ioana Alesutan, Dietmar Kuhl, Bernd J. Pichler, Venkanna Pasham
Publikováno v:
Basic Research in Cardiology. 107
Sustained increase of cardiac workload is known to trigger cardiac remodeling with eventual development of cardiac failure. Compelling evidence points to a critical role of enhanced cardiac Na(+)/H(+) exchanger (NHE1) activity in the underlying patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8680e8a317d9757b9a946b8779f3f4eb
https://doi.org/10.1007/s00395-011-0236-2
https://doi.org/10.1007/s00395-011-0236-2
Publikováno v:
BMC Nephrology
Background Anemia in end stage renal disease is attributed to impaired erythrocyte formation due to erythropoietin and iron deficiency. On the other hand, end stage renal disease enhances eryptosis, the suicidal erythrocyte death characterized by cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4948b52c827346381b5f2ed57b1209a9