Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mohamed Shaimi"'
Publikováno v:
Front. Heat Mass Transf.. 20
Publikováno v:
Proceedings of the 8th World Congress on Mechanical, Chemical, and Material Engineering.
Publikováno v:
International Conference on Fluid Flow, Heat and Mass Transfer.
Autor:
Mohamed Shaimi, Jayesh Mistry, Huw D. Lewis, Jonathan D. Best, Christopher J. Welch, Andrew Madin, Michael Reilly, Fraser Murray, Timothy Harrison, Jonathan D.J. Wrigley, Ian Collins, Mark S. Shearman, Laura Catherine Cooper, Earl E. Clarke, Linda Elizabeth Keown
Publikováno v:
Journal of Medicinal Chemistry. 52:3441-3444
The development of potent gamma-secretase inhibitors having substituted heterocycles attached to a benzobicyclo[4.2.1]nonane core is described. This work led to the identification of [6S,9R,11R]-2',3',4',5,5',6,7,8,9,10-decahydro-2-(5-(4-fluorophenyl
Autor:
Derek W. Henderson, Christopher J. Welch, Dave Conlon, Mohamed Shaimi, Brenda Pipik, David J. Schenk
Publikováno v:
Organic Process Research & Development. 14:905-907
Preparative chromatography was used to overcome the difficult selectivity challenge of accessing a single isomer of a mono tert-butyldimethylsilyl (TBDMS) derivative of an unsymmetrical diol. Chromatographic purification allowed rapid purification of
Publikováno v:
Journal of chromatography. A. 865(1-2)
In this paper, we describe the direct, preparative enantioselective chromatography of racemic ( rac )-propranolol hydrochloride (HCl) and rac -thioridazine·HCl using Chiralpak AD chiral stationary phase and mobile phase systems containing carbon dio
Autor:
David L. Hughes, Derek W. Henderson, Enrique Vazquez, Christopher J. Welch, Ian W. Davies, Audrey Wong, Jeffrey T. Kuethe, Mohamed Shaimi
Publikováno v:
Organic & Biomolecular Chemistry. 2:168
A facile preparation of enantiopure ethyl (1S,5S,6S)-6-fluoro-2-oxobicyclo[3.1.0]hexane-6-carboxylate 1 is described. The key feature of the synthesis involves copper-catalyzed enantioselective intramolecular cyclopropanation of a diazoketone to form
Autor:
Linda E. Keown, Ian Collins, Laura C. Cooper, Timothy Harrison, Andrew Madin, Jayesh Mistry, Michael Reilly, Mohamed Shaimi, Christopher J. Welch, Earl E. Clarke, Huw D. Lewis, Jonathan D. J. Wrigley, Jonathan D. Best, Fraser Murray, Mark S. Shearman
Publikováno v:
Journal of Medicinal Chemistry; Jun2009, Vol. 52 Issue 11, p3441-3444, 4p