Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Mohamed Samir Ahmed, Zaki"'
1
Akademický článek
Curcumin attenuates doxorubicin-induced cardiotoxicity via suppressing oxidative Stress, preventing inflammation and apoptosis: Ultrastructural and computational approaches
Autor: Ayed A. Shati, Refaat A. Eid, Attalla F. El-kott, Youssef A. Alqahtani, Abdullah S. Shatoor, Mohamed Samir Ahmed Zaki
Publikováno v: Heliyon, Vol 10, Iss 5, Pp e27164- (2024)
Currently, doxorubicin (DOX) is one of the medications commonly used in chemotherapy to treat different types of tumors.Nonetheless, despite being effective in multiple tumors, yet its use is limited owing to its cytotoxic effects, the therapeutic us
Externí odkaz: https://doaj.org/article/4be8d49798fe4675966d9e0dbc9594ad
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2
Akademický článek
Fish oil protects against corn oil-induced cardiac insulin resistance and left ventricular dysfunction in rats via upregulation of PPAR-β/γ and inhibition of diacylglycerol/PCK axis activation
Autor: Refaat A. Eid, Mubarak Al-Shraim, Samy M. Eleawa, Mohamed Samir Ahmed Zaki, Attalla Farag El-kott, Muhammad Alaa Eldeen, Mahmoud A. Alkhateeb, Mohammed Alassiri, Hussain Alderah
Publikováno v: Journal of Functional Foods, Vol 56, Iss , Pp 342-352 (2019)
This study investigated the effects corn oil (CO) and different ratios of corn oil plus fish oil (FO) on insulin signaling in rat's heart. Adult male rats were fed low (LFD) or isocaloric high-fat diets (HFDs) of CO alone or CO + FO (ratios of 9:1 or
Externí odkaz: https://doaj.org/article/95a3ce40069d48fcbafdf288850badaf
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8
Exendin-4 Protects Against Myocardial Ischemia-Reperfusion Injury by Upregulation of SIRT1 and SIRT3 and Activation of AMPK
Autor: Mashael Mohammed Bin-Meferij, Samah A. Alharbi, Mubarak Al-Shraim, Muhammad Alaa Eldeen, Hussain Aldera, Refaat A. Eid, Mahmoud A. Alkhateeb, Fahmy El-Sayed, Attalla F. El-kott, Mohamed Samir Ahmed Zaki, Mohammad A. Khalil, Samy M Eleawa
Publikováno v: Journal of Cardiovascular Translational Research. 14:619-635
This study evaluated if the cardioprotective effect of Exendin-4 against ischemia/reperfusion (I/R) injury in male rats involves modulation of AMPK and sirtuins. Adult male rats were divided into sham, sham + Exendin-4, I/R, I/R + Exendin-4, and I/R
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d144eee75bda48ead6978bcd5195bf9b
https://doi.org/10.1007/s12265-020-09984-5
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10
Exendin-4 Ameliorates Cardiac Remodeling in Experimentally Induced Myocardial Infarction in Rats by Inhibiting PARP1/NF-κB Axis in A SIRT1-Dependent Mechanism
Autor: Samy M Eleawa, Mohamed Samir Ahmed Zaki, Fahmy El-Sayed, Abd Al‐Rahman Salem Al‐Shudiefat, Attalla F. El-kott, Hussain Aldera, Refaat A. Eid, Muhammad Alaa Eldeen, Samah A. Alharbi
Publikováno v: Cardiovascular Toxicology. 20:401-418
Sirt1 is a potent inhibitor of both poly(ADP-ribose) polymerases1 (PARP1) and NF-kB. This study investigated the cardioprotective effect of exendin-4 on cardiac function and remodeling in rats after an expreimentally-induced myocardial infarction (MI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c0f3e0057602a9e665bf81e38ec40e
https://doi.org/10.1007/s12012-020-09567-5
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