Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mohamed Osama Ali Abdalla"'
Autor:
Mohamed Osama Ali Abdalla, Tatsuro Yamamoto, Kazumitsu Maehara, Jumpei Nogami, Yasuyuki Ohkawa, Hisashi Miura, Rawin Poonperm, Ichiro Hiratani, Hideki Nakayama, Mitsuyoshi Nakao, Noriko Saitoh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Long term estrogen deprivation can result in apoptosis in breast cancer cells. Here, the authors show that this apoptosis is induced by the long-range chromatin interaction of loci containing the ESR1 and FOXO 3 genes, resulting in FOXO 3-mediated ap
Externí odkaz:
https://doaj.org/article/942f290119a6494eac46f39607ac50db
Autor:
Hideki Nakayama, Yasuyuki Ohkawa, Hisashi Miura, Noriko Saitoh, Rawin Poonperm, Kazumitsu Maehara, Tatsuro Yamamoto, Jumpei Nogami, Mohamed Osama Ali Abdalla, Mitsuyoshi Nakao, Ichiro Hiratani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
MCF7 cells acquire estrogen-independent proliferation after long-term estrogen deprivation (LTED), which recapitulates endocrine therapy resistance. LTED cells can become primed for apoptosis, but the underlying mechanism is largely unknown. We previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0646180633d5862cead2e070f2831952
https://doi.org/10.1038/s41467-019-11378-4
https://doi.org/10.1038/s41467-019-11378-4
Autor:
Joeji Wakimoto, Seiji Okada, Yamoto Motooka, Shinji Kudoh, Yoshiki Naito, Mohamed Osama Ali Abdalla, Koichi Higaki, Yuichi Ishikawa, Wael Abdo Hassan, Kosuke Fujino, Shin-ichiro Takebayashi, Mituyoshi Nakao, Takaaki Ito, Yonosuke Sato
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 97(8)
Combined small-cell lung carcinoma (cSCLC) is composed of small-cell lung carcinoma (SCLC) admixed with non-small-cell lung carcinoma (NSCLC). Evaluating the molecular differences between SCLC and NSCLC could lead to a better understanding of the pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a321e0173a5eaed4fc010249ff0fe27
https://pubmed.ncbi.nlm.nih.gov/28414324
https://pubmed.ncbi.nlm.nih.gov/28414324
Autor:
Saori, Tomita, Mohamed Osama Ali, Abdalla, Saori, Fujiwara, Tatsuro, Yamamoto, Hirotaka, Iwase, Mitsuyoshi, Nakao, Noriko, Saitoh
Publikováno v:
Wiley interdisciplinary reviews. RNA. 8(2)
The cell nucleus is highly organized and functionally compartmentalized. Double-stranded naked DNA is complexed with core histones and assembled into nucleosomes and chromatin, which are surrounded by nuclear domains composed of RNAs and proteins. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4e03c7a3a110d79335200a115472194
https://pubmed.ncbi.nlm.nih.gov/27489248
https://pubmed.ncbi.nlm.nih.gov/27489248
Autor:
Kanako Niimori-Kita, Yamato Motooka, Shinji Kudoh, Mohamed Osama Ali Abdalla, Yonosuke Sato, Koki Hasegawa, Takaaki Ito, Wael Abdo Hassan, Ichiro Kubota, Kosuke Fujino, Joeji Wakimoto, Hironori Kobayashi, Makoto Suzuki
Publikováno v:
The American journal of pathology. 185(12)
Insulinoma-associated protein 1 (INSM1) is expressed exclusively in embryonic developing neuroendocrine (NE) tissues. INSM1 gene expression is specific for small-cell lung cancer (SCLC), along with achaete-scute homolog-like 1 (ASCL1) and several NE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bc16ad990ef97b77571f47872509df
https://pubmed.ncbi.nlm.nih.gov/26482608
https://pubmed.ncbi.nlm.nih.gov/26482608
Autor:
Mohamed Osama Ali Abdalla, Noriko Saitoh, Mitsuyoshi Nakao, Saori Tomita, Saori Fujiwara, Hirotaka Iwase, Yasuyuki Ohkawa, Kazumitsu Maehara, Haruka Matsumori
Publikováno v:
Nature Communications
Estrogen receptor-α (ER)-positive breast cancer cells undergo hormone-independent proliferation after deprivation of oestrogen, leading to endocrine therapy resistance. Up-regulation of the ER gene (ESR1) is critical for this process, but the underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf70b5d15f632cbbddaa514f2d5e17f
https://pubmed.ncbi.nlm.nih.gov/25923108
https://pubmed.ncbi.nlm.nih.gov/25923108
Autor:
Tatsuro Yamamoto, Hirotaka Iwase, Noriko Saitoh, Saori Fujiwara, Saori Tomita, Mohamed Osama Ali Abdalla, Mitsuyoshi Nakao
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 8:e1384
The cell nucleus is highly organized and functionally compartmentalized. Double-stranded naked DNA is complexed with core histones and assembled into nucleosomes and chromatin, which are surrounded by nuclear domains composed of RNAs and proteins. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7af6be92f9944c5d0aa61c3114f6dd2
https://doi.org/10.1002/wrna.1384
https://doi.org/10.1002/wrna.1384