Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mohamed Nabil Aboul-Enein"'
Publikováno v:
Drug Development Research
The 7-chloro-4-(piperazin-1-yl)quinoline structure is an important scaffold in medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores diverse pharmacological profiles such as: antimalarial, antiparasitic, anti-HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc37e9b3ce5a2b7fefcf325da2466517
https://doi.org/10.1002/ddr.21678
https://doi.org/10.1002/ddr.21678
Autor:
Aida A. El-Azzouny, Rasha M. Hassan, Mohammed S. Abdel-Maksoud, Mohamed Nabil Aboul-Enein, Chang-Hyun Oh
Publikováno v:
Bioorganic chemistry. 117
A new series of N-(2-((4-(1,3-diphenyl-1H-pyrazol-4-yl)pyridine sulfonamide derivatives 11a-o were designed and synthesized based on our previous works. The new series was tested for its anticancer and anti-inflammatory effects. The anticancer profil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fcf199c8ffc724c3ac8582ba5f673b
https://pubmed.ncbi.nlm.nih.gov/34678604
https://pubmed.ncbi.nlm.nih.gov/34678604
Publikováno v:
Bioorganic Chemistry. 71:135-145
A series of (1-(benzyl (aryl) amino) cyclohexyl) methyl esters 7a-n were prepared and screened for their anticonvulsant profile. Screening of these esters 7a-n and their starting alcohols 6a and 6b revealed that compound 7k was the most potent one in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6935b7e2402c7ae05235e986b712c24c
https://doi.org/10.1016/j.bioorg.2017.01.021
https://doi.org/10.1016/j.bioorg.2017.01.021
Autor:
Walaa Hamada Abd-Allah, Mohamed Nabil Aboul-Enein, Aida A. El-Azzouny, Mona E Aboutabl, Rasha M. Hassan
Publikováno v:
Bioorganic chemistry. 94
In this work a set of novel derivatives of parabanic acid 9a-d, 12a-d and 13a-d was synthesized and their anticonvulsant potential was evaluated. All the compounds under investigation exhibited anticonvulsant activity in both scPTZ and MES tests. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500655c8b86d69b487132b6f10b8597e
https://pubmed.ncbi.nlm.nih.gov/31831160
https://pubmed.ncbi.nlm.nih.gov/31831160
Autor:
Aida A. El-Azzouny, Mohamed Nabil Aboul-Enein, Ola A. Saleh, Hazem A. Ghabbour, Mohamed I. Attia, Rasha M. Hassan
Publikováno v:
Zeitschrift für Kristallographie-New Crystal Structures, Vol 232, Iss 3, Pp 433-435 (2017)
C28H37N3O2, monoclinic, P21/c (no. 14), a = 11.0454(4) Å, b = 21.9125(8) Å, c = 11.6544(4) Å, β = 111.783(1)°, V = 2619.33(16) Å3, Z = 4, Rgt(F) = 0.0658, wRref(F2) = 0.1940, T = 293(2) K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14a52cced752726c31fd761bc39a9b3
https://doi.org/10.1515/ncrs-2016-0304
https://doi.org/10.1515/ncrs-2016-0304
Autor:
Hazem A. Ghabbour, Ola A. Saleh, Rasha M. Hassan, Mohamed I. Attia, Mohamed Nabil Aboul-Enein, Aida A. El-Azzouny
Publikováno v:
Zeitschrift für Kristallographie - New Crystal Structures. 232:465-467
C26H31N3O3, monoclinic, P21/c (no. 14), a = 8.8698(5) Å, b = 24.4835(13) Å, c = 11.7890(6) Å, β = 113.024(3)°, V = 2356.2(2) Å3, Z = 4, R gt(F) = 0.0606, wR ref(F 2) = 0.1597, T = 293(2) K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7247a749853db45921b63e7a0d96889
https://doi.org/10.1515/ncrs-2016-0319
https://doi.org/10.1515/ncrs-2016-0319
Autor:
Kamilia M. Amin, Mohamed Nabil Aboul-Enein, Mona E Aboutabl, Mai I Abo-Elmagd, Aida A. El-Azzouny
Publikováno v:
Archiv der Pharmazie. 351(12)
A series of 1-((2-hydroxyethyl)(aryl)amino)-N-substituted cycloalkanecarboxamides IXa-l and their acetate esters Xa-l were designed and synthesized as new anticovulsant agents. The evaluation of the anticonvulsant effect was performed in vivo by subc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8fc34d292142f197164ba5676428ec
https://pubmed.ncbi.nlm.nih.gov/30461033
https://pubmed.ncbi.nlm.nih.gov/30461033
Autor:
Kamilia M. Amin, Yousreya Ali Maklad, Rasha M. Hassan, Aida A. El-Azzouny, Mohamed Nabil Aboul-Enein, Ola A. Saleh
Publikováno v:
Archiv der Pharmazie. 348:575-588
A series of novel spiroimidazolidinone derivatives 6a-d and 8a-x were synthesized and biologically evaluated for their anticonvulsant activity in the maximal electroshock seizure (MES) assay and the subcutaneous pentylenetetrazole (scPTZ) screening t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7397f17981329256d9d7238e2ca85982
https://doi.org/10.1002/ardp.201500092
https://doi.org/10.1002/ardp.201500092
Autor:
Mohamed Nabil Aboul-Enein, Ola A. Saleh, Hassan Y. Aboul-Enein, Aida A. El-Azzouny, Rasha M. Hassan, Kamilia M. Amin
Publikováno v:
Journal of chromatographic science. 56(2)
Enantioseparation of substituted 1,3-diazaspiro[4.5]decan-4-ones (1-14) was achieved using different polysaccharide type chiral stationary phases (CSPs), namely, Chiralcel OJ, Chiralcel OD and Lux-Amylose-2 using different mobile phases which were ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c84bc11e4cc68180ceb62fce6da9ceb
https://pubmed.ncbi.nlm.nih.gov/29190324
https://pubmed.ncbi.nlm.nih.gov/29190324
Autor:
Mohammed Farrag El-Behairy, Amany Sayed Maghraby, Aida A. El-Azzouny, Mona E Aboutabl, Mohamed Nabil Aboul-Enein, Y. A. Maklad, Ola A. Saleh
Publikováno v:
European Journal of Chemistry. 5:488-496
New series of arylthiadiazole hydrazinecarboxamides (5a-e) have been synthesized by hydrazinolysis of carbamates (4a-e) and spectrally characterized. The new candidates have been screened for their anticonvulsant and immunomodulatory activities. Comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f931073dd3e690e7ec7b8dd3d31e387
https://doi.org/10.5155/eurjchem.5.3.488-496.1073
https://doi.org/10.5155/eurjchem.5.3.488-496.1073