Prevalence of TP53 gene Pro72Arg (rs1042522) single nucleotide polymorphism among Egyptian breast cancer patients

Autor: Shaza Ahmed, Gehan Safwat, Mohamed M. Moneer, AbdelWahab El Ghareeb, Ahmed A. El Sherif, Samah A. Loutfy

Publikováno v: Egyptian Journal of Medical Human Genetics, Vol 24, Iss 1, Pp 1-7 (2023)

Abstract Background The P53 protein has an essential role in several cellular processes, including DNA repair, apoptosis, and cell cycle arrest. The pathophysiology of many cancer types has frequently been linked to polymorphisms in the TP53 locus. O

Externí odkaz: https://doaj.org/article/0d63fe3cca3f4386884d341da57c441e

Abstract 5842: High resolution melting technique as an economic prognostic tool for identifying deleterious mutations in BRCA1, BRCA2, and P53 genes amongst breast cancer women

Autor: Shaza Ahmed, Nasra F. Abdel Fattah, Shimaa A. Metwally, Marwa A. Abdelwahed, Hossam Taha Mohamed, Sara H. Agwa, AbdelWahab El Ghareeb, Gehan Safwat, Ahmed A. El Sherif, Mohamed M. Moneer, Samah A. Loutfy

Publikováno v: Cancer Research. 82:5842-5842

Introduction: The incidence of breast cancer (BC) has substantially increased among women younger than 50. Due to fragile economic situation in the middle east and lack of awareness, BC women are characterized by late diagnosis and thus, there is an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18765e91cadd213c05d445d1b49dd00e
https://doi.org/10.1158/1538-7445.am2022-5842

Pathological Assessment of the Response of Locally Advanced Breast Cancer to Neoadjuvant Chemotherapy and Its Implications for Surgical Management

Autor: Monir H. El-Didi, Soheir S Makarem, Hussein M. Khaled, Mohamed M. Moneer

Publikováno v: Surgery Today. 30:249-254

The effectiveness of breast-conserving surgery for patients with locally advanced breast cancer (LABC) after neoadjuvant chemotherapy (NACT) is still a controversial issue, and variable incidences of locoregional failures have been reported. The pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe9e0b58ae835be40e4013f0eb6b02d
https://doi.org/10.1007/s005950050054

Prevalence of MMTV-Like env Sequences and Its Association with BRCA1/2 Genes Mutations Among Egyptian Breast Cancer Patients.

Autor: Loutfy SA; Virology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt., Abdallah ZF; Virology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt., Shaalan M; Surgical Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt., Moneer M; Surgical Oncology Department, Materia Teaching Hospital, Cairo, Egypt., Karam A; Surgical Oncology Department, Materia Teaching Hospital, Cairo, Egypt., Moneer MM; Biostatistics and Epidemiology Department, National Cancer Institute, Cairo University, Cairo, Egypt., Sayed IM; Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA, USA., Abd El-Hafeez AA; Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, 92093, USA., Ghosh P; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, 92093, USA.; Department of Medicine, University of California, San Diego, La Jolla, CA, 92093, USA.; Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA., Zekri AN; Virology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.

Publikováno v: Cancer management and research [Cancer Manag Res] 2021 Mar 26; Vol. 13, pp. 2835-2848. Date of Electronic Publication: 2021 Mar 26 (Print Publication: 2021).