Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mohamed M. Bekhite"'
Publikováno v:
Cells, Vol 10, Iss 12, p 3483 (2021)
A comprehensive understanding of the pathophysiology and cellular responses to drugs in human heart disease is limited by species differences between humans and experimental animals. In addition, isolation of human cardiomyocytes (CMs) is complicated
Externí odkaz:
https://doaj.org/article/6bbc9464d5ff407b9f793df6d0b63487
Autor:
Tom Kretzschmar, Mohamed M. Bekhite, Jasmine M. F. Wu, Daniela Haase, Martin Förster, Tina Müller, Sandor Nietzsche, Martin Westermann, Marcus Franz, Markus H. Gräler, P. Christian Schulze
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11852 (2021)
Doxorubicin (Dox) is a chemotherapeutic agent with cardiotoxicity associated with profibrotic effects. Dox increases ceramide levels with pro-inflammatory effects, cell death, and fibrosis. The purpose of our study was to identify the underlying cera
Externí odkaz:
https://doaj.org/article/6c46b5dcf5a94933a40b90adf86c3617
Autor:
Jurgen Bogoviku, Mohamed M. Bekhite, Ali Hamadanchi, Julian G. Westphal, Sven Möbius-Winkler, Daniel A. Morris, Marat Fudim, Tarek Bekfani, P. Christian Schulze, Steffen Derlien, Shun Ijuin, Jenny Nisser, Rüdiger C. Braun-Dullaeus
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 8, Iss 6, Pp 4528-4538 (2021)
ESC Heart Failure, Vol 8, Iss 6, Pp 4528-4538 (2021)
Aims Left atrial strain (LAS) and skeletal muscle endurance demonstrate a linear relationship to peak VO2. Less is known about the relationship between central (cardiac) and peripheral (muscle endurance) limitations of exercise capacity in patients w
Autor:
Boris Greber, Tarek Bekfani, Mohamed M. Bekhite, Marcus Franz, Jasmine M F Wu, Tom Kretzschma, Maria Wartenberg, Tina Müller, Christian Schulze, Andres González-Delgado, Markus H. Gräler
BackgroundOversupply of fatty acids (FAs) to cardiomyocytes (CMs) is associated with increased ceramide content and elevated the risk of lipotoxic cardiomyopathy. Here we investigate the role of ceramide accumulation on mitochondrial function and mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e764f3280587b2018f6e6bf3c50b0d93
https://doi.org/10.21203/rs.3.rs-47563/v1
https://doi.org/10.21203/rs.3.rs-47563/v1
Autor:
Desirée M, Möhner, Anne, Bernhardt, Mohamed M, Bekhite, P Christian, Schulze, Heinrich, Sauer, Maria, Wartenberg
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1867(11)
Ca
Autor:
Heinrich Sauer, P. Christian Schulze, Maria Wartenberg, Anne Bernhardt, Mohamed M. Bekhite, Desirée M. Möhner
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1867:118796
Ca2+-activated potassium (KCa) channels of small and intermediate conductance influence proliferation, apoptosis, and cell metabolism. We analysed whether prolonged activation of KCa channels by zoxazolamine (ZOX) induces differentiation of mouse emb
Autor:
Nabil K. El-Fiky, Ibrahim K. El-Shourbagy, Andreas Finkensieper, Mohamed M. Bekhite, Maria Wartenberg, Heinrich Sauer, Khaled M. Omar, Fouad A. Abou-Zaid
Publikováno v:
Reproductive Toxicology. 65:46-58
Man-made magnetic fields (MFs) may exert adverse effects on mammalian embryonic development. Herein, we analysed the effect of 10mT 50Hz sinusoidal (AC) or static (DC) MFs versus 1mT MFs on embryonic development of mice. Exposure for 20days during ge
Autor:
Jorge Hurtado-Oliveros, Heinrich Sauer, Maria Wartenberg, Fatemeh Sharifpanah, Sepali De Silva, Mohamed M. Bekhite, Klaus T. Preissner
Publikováno v:
Free Radical Biology and Medicine. 89:1203-1217
Objective Cell injury releases nucleic acids supporting inflammation and stem cell activation. Here, the impact of extracellular ribonucleic acid, especially transfer RNA (ex-tRNA), on vasculogenesis and leukopoiesis of mouse embryonic stem (ES) cell
Publikováno v:
Cell and Tissue Research. 358:443-452
The β-adrenoceptor antagonist Propranolol has been successfully used to treat infantile hemangioma. However, its mechanism of action is so far unknown. The hypothesis of this research was that β-adrenoceptor antagonists may interfere with endotheli
Autor:
Stefan Schultze-Mosgau, Stephanie Huse, Hans-Reiner Figulla, Heinrich Sauer, Mohamed M. Bekhite, Jennifer Rebhan, Andreas Finkensieper, Maria Wartenberg
Publikováno v:
Stem Cells and Development. 23:333-351
The plasticity of human adipose tissue-derived stem cells (hASCs) is promising, but differentiation in vitro toward endothelial cells is poorly understood. Flow cytometry demonstrated that hASCs isolated from excised fat tissue were positive for CD29