Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mohamed H. Noureldein"'
Autor:
Kevin S. Chen, Mohamed H. Noureldein, Lisa M. McGinley, John M. Hayes, Diana M. Rigan, Jacquelin F. Kwentus, Shayna N. Mason, Faye E. Mendelson, Masha G. Savelieff, Eva L. Feldman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
IntroductionStem cells are a promising therapeutic in Alzheimer’s disease (AD) given the complex pathophysiologic pathways involved. However, the therapeutic mechanisms of stem cells remain unclear. Here, we used spatial transcriptomics to elucidat
Externí odkaz:
https://doaj.org/article/34fd950a9d53474a8e6ce622502373c2
Autor:
Rosemary E. Henn, Kai Guo, Sarah E. Elzinga, Mohamed H. Noureldein, Faye E. Mendelson, John M. Hayes, Diana M. Rigan, Masha G. Savelieff, Junguk Hur, Eva L. Feldman
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106164- (2023)
Summary: Obesity is a growing global concern in adults and youth with a parallel rise in associated complications, including cognitive impairment. Obesity induces brain inflammation and activates microglia, which contribute to cognitive impairment by
Externí odkaz:
https://doaj.org/article/238ca0dd57094fe580f23e687c6af364
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-23 (2021)
Abstract Background Doxorubicin (DOX), a widely used chemotherapeutic agent, can cause neurodegeneration in the brain, which leads to a condition known as chemobrain. In fact, chemobrain is a deteriorating condition which adversely affects the lives
Externí odkaz:
https://doaj.org/article/cbc843482bfe4acd953ca78840affa0e
Autor:
Rosemary E. Henn, Mohamed H. Noureldein, Sarah E. Elzinga, Bhumsoo Kim, Masha G. Savelieff, Eva L. Feldman
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105766- (2022)
Dementia is a complex set of disorders affecting normal cognitive function. Recently, several clinical studies have shown that diabetes, obesity, and components of the metabolic syndrome (MetS) are associated with cognitive impairment, including deme
Externí odkaz:
https://doaj.org/article/df8853ff2e414c5497ea92327495a485
Publikováno v:
Diabetes. 71
The prevalence of the metabolic syndrome (MetS) is increasing worldwide due in part to the increased consumption of a Western diet. MetS is associated with peripheral neuropathy (PN) . PN develops in a cell non-autonomous manner with involvement of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d4d9e5712087e606a2e9965d26d707f
https://doi.org/10.2337/db22-460-p
https://doi.org/10.2337/db22-460-p
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071622643
Methods in Molecular Biology ISBN: 9781071622643
Neurological diseases are highly prevalent and constitute a significant cause of mortality and disability. Neurological disorders encompass a heterogeneous group of neurodegenerative conditions, broadly characterized by injury to the peripheral and/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b7407a55ad5c001407f0e0b7c5107e
https://pubmed.ncbi.nlm.nih.gov/35437727
https://pubmed.ncbi.nlm.nih.gov/35437727
Autor:
Natalie Youssef, Frédéric Harb, Assaad A. Eid, Mohamed H. Noureldein, Rachel Njeim, Hilda E. Ghadieh, Nassim Fares, Sami T. Azar
Publikováno v:
Biomedicines; Volume 9; Issue 10; Pages: 1360
Biomedicines, Vol 9, Iss 1360, p 1360 (2021)
Biomedicines
Biomedicines, Vol 9, Iss 1360, p 1360 (2021)
Biomedicines
Diabetic kidney disease (DKD), a serious diabetic complication, results in podocyte loss and proteinuria through NADPH oxidases (NOX)-mediated ROS production. DUOX1 and 2 are NOX enzymes that require calcium for their activation which enters renal ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481efb3273d711675cd8aa744bba1376
Autor:
Frédéric Harb, Maysaa Hamza, Batoul Dia, Ramzi Sabra, Mirella El Khoury, Nadim S. Azar, Nahed Mogharbil, Lynn M. Alaeddine, Assaad A. Eid, Mohamed H. Noureldein
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 235
Diabetic cardiomyopathy (DCM) is a well-established complication of type 1 and type 2 diabetes associated with a high rate of morbidity and mortality. DCM is diagnosed at advanced and irreversible stages. Therefore, it is of utmost need to identify n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919649a6fa4f7c7eb08b489b57bd57c3
https://pubmed.ncbi.nlm.nih.gov/33746109
https://pubmed.ncbi.nlm.nih.gov/33746109
Autor:
Assaad A. Eid, Mohamed H. Noureldein
Publikováno v:
Diabetes. 69
Diabetes changes the microbiota of the host, a condition known as dysbiosis. Dysbiosis have emerged to be an important contributing factor for the pathogenesis of diabetes and diabetes-associated colorectal cancer. In this study we tangled some of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b531d324ddd3a92e5b639ea38c7a5d3
https://doi.org/10.2337/db20-1646-p
https://doi.org/10.2337/db20-1646-p
Publikováno v:
Diabetesmetabolism. 47(3)
The emergence of immune checkpoint inhibitors in the arsenal of cancer immunotherapy was a breakthrough which provided hope to many cancer patients. However, not long has passed since their discovery that some adverse effects were associated with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4010f1501e9daad4ce06ecd8131f3e15
https://pubmed.ncbi.nlm.nih.gov/33010422
https://pubmed.ncbi.nlm.nih.gov/33010422