Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mohamed Ghilan"'
Autor:
Jessica M. Simpson, Joana Gil-Mohapel, Mahmoud A. Pouladi, Mohamed Ghilan, Yuanyun Xie, Michael R. Hayden, Brian R. Christie
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 249-260 (2011)
Perturbations in neurogenesis in the adult brain have been implicated in impaired learning and memory. In the present study, we investigated which stages of the neurogenic process are affected in the transgenic YAC128 mouse model of Huntington diseas
Externí odkaz:
https://doaj.org/article/41e68437097a457b898bbc4609b4e210
Autor:
Patricia S. Brocardo, Joana Gil-Mohapel, Mohamed Ghilan, Luis E.B. Bettio, Athena Noonan, Brian R. Christie
Publikováno v:
Behavioural brain research. 350
Fragile X syndrome (FXS) is the most common form of inherited intellectual impairment. The Fmr1-/y mouse model has been previously shown to have deficits in context discrimination tasks but not in the elevated plus-maze. To further characterize this
Autor:
Patricia S. Brocardo, Brett N. Hryciw, Crystal A. Bostrom, Mohamed Ghilan, Brian R. Christie, Joana Gil-Mohapel
Publikováno v:
Neurobiology of Disease, Vol 77, Iss, Pp 26-34 (2015)
The fragile X mental retardation protein (FMRP) is an important regulator of protein translation, and a lack of FMRP expression leads to a cognitive disorder known as fragile X syndrome (FXS). Clinical symptoms characterizing FXS include learning imp
Autor:
B.D Eadie, J. Chiu, Brett N. Hryciw, Ryan C. Wortman, Christine J. Fontaine, S. Sawchuk, Mohamed Ghilan, Brian R. Christie, A. Truesdell, Alicia Meconi, E. Truesdell, Suk Yu Yau, Crystal A. Bostrom, Christine Chiu
Publikováno v:
Neurobiology of Disease, Vol 96, Iss, Pp 261-270 (2016)
Fragile-X syndrome (FXS) is caused by the transcriptional repression of the Fmr1 gene resulting in loss of the Fragile-X mental retardation protein (FMRP). This leads to cognitive impairment in both male and female patients, however few studies have
Publikováno v:
Brain Research. 1406:84-105
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by an unstable expansion of CAG repeats in the HD gene. The symptoms include cognitive dysfunction and severe motor impairments. The neuropathology is characterized
Autor:
Mohamed Ghilan, Jessica M. Simpson, Brian R. Christie, Mahmoud A. Pouladi, Yuanyun Xie, Joana Gil-Mohapel, Michael R. Hayden
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 2, Pp 249-260 (2011)
Perturbations in neurogenesis in the adult brain have been implicated in impaired learning and memory. In the present study, we investigated which stages of the neurogenic process are affected in the transgenic YAC128 mouse model of Huntington diseas
Autor:
Brett N. Hryciw, Joana Gil-Mohapel, Brian R. Christie, Mohamed Ghilan, Jessica M. Simpson, Crystal A. Bostrom
Publikováno v:
Brain research. 1581
Huntington's disease (HD) is a progressive and fatal neurodegenerative disorder caused by a polyglutamine expansion in the gene encoding the protein huntingtin. The disease progresses over decades, but often patients develop cognitive impairments tha
Autor:
Alaa Alshaibat, Mohamed Ghilani, Mohammad Sidiq, Wadha Alenazi, Mohammad Qasim, Faizan Kashoo, Mehrunnisha Ahmad
Publikováno v:
International Journal of Physiotherapy, Vol 8, Iss 2 (2021)
Background: A 15-year-old boy met with a road traffic accident in October 2016. The patient sustained a complete spinal cord injury at T11, resulting in paraplegia. Case Description: Later in 2019, the patient was admitted to our hospital with bilate
Externí odkaz:
https://doaj.org/article/b65b6755c5964615992ae9d5f3bdaaee