Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mohamed F. El-Mansy"'
Publikováno v:
Arkivoc. 2021:110-137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd8bbb3ed274f6e487d6e727bf786c0f
https://doi.org/10.24820/ark.5550190.p011.494
https://doi.org/10.24820/ark.5550190.p011.494
Publikováno v:
Organic Letters. 22:2999-3003
To gauge the feasibility of carbenoid eliminative cross-coupling for the synthesis of polyfunctional alkenes, a P-glycoprotein inhibitor containing an (E)-configured 4-chromanylidene-type trisubsti...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c2703040bc8471c4c081695ed60b99
https://doi.org/10.1021/acs.orglett.0c00755
https://doi.org/10.1021/acs.orglett.0c00755
Autor:
Weam S. Elserwy, Eman Y. Ahmed, Moaaz R. Abd Elaziz, Mohamed F. El-Mansy, Aya M. Serry, Abdelrahman M. Salem, Kenzi H. Elsayed, Andrew M. Abdou, Basel A. Abdelrahman
Publikováno v:
Bioorganicmedicinal chemistry letters. 48
The present work represents the design and synthesis of some azaheterocyclic coumarin derivatives which are evaluated as anti-lung cancer agents. Ten out of the twenty azaheterocyclic compounds showed superior activity than the standard drug staurosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8796664a1ef67b42bb69ed2851b18cc
https://pubmed.ncbi.nlm.nih.gov/34246754
https://pubmed.ncbi.nlm.nih.gov/34246754
Publikováno v:
Organic letters. 22(8)
To gauge the feasibility of carbenoid eliminative cross-coupling for the synthesis of polyfunctional alkenes, a P-glycoprotein inhibitor containing an (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::965ffde1a5b2c72f88d9e266bb152f6b
https://pubmed.ncbi.nlm.nih.gov/32227909
https://pubmed.ncbi.nlm.nih.gov/32227909
Publikováno v:
Angewandte Chemie. 130:9255-9259
The efficient, 12-14 step (LLS) total synthesis of (-)-halenaquinone has been achieved. Key steps in the synthetic sequence include: (a) proline sulfonamide-catalyzed, Yamada-Otani reaction to establish the C6 all-carbon quaternary stereocenter, (b)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e43ac16cc491f8ad8c6e4a037c19c77
https://doi.org/10.1002/ange.201805370
https://doi.org/10.1002/ange.201805370
Autor:
Paul R. Blakemore, Jan F. Stevens, Mohamed F. El-Mansy, Adrian F. Gombart, Duncan C. Ellinwood, Claudia S. Maier, Layhna S. Plagmann
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 60:639-648
Xanthohumol [(E)-6´-methoxy-3´-(3-methylbuten-2-yl)-2´,4´,4´´-trihydroxychalcone], the principal prenylated flavonoid from hops, has a complex bioactivity profile and 13C-labelled isotopomers of this compound are of potential use as molecular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72812f5ae6c46a1c753be12c25d27c5
https://doi.org/10.1002/jlcr.3571
https://doi.org/10.1002/jlcr.3571
Autor:
Eman Y. Ahmed, Mohamed F. El-Mansy, Nehad A. Abdel Latif, Omaima M. Abdelhafez, Weam S. Elserwy
Publikováno v:
Bioorganicmedicinal chemistry. 28(5)
Twenty five newly synthesized coumarin scaffold based derivatives were assayed for their in vitro anticancer activity against MCF-7 breast and PC-3 prostate cancer cell lines and were further assessed for their in vitro VEGFR-2 kinase inhibitory acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d568955156d9a676921cbcef5366e01f
https://pubmed.ncbi.nlm.nih.gov/31992477
https://pubmed.ncbi.nlm.nih.gov/31992477
Benzyl imidazole was successfully lithiated using n-BuLi at −78 °C and verified by deuterium incorporation. The chemical reaction of the lithiated benzimidazole was explored with a series of different electrophiles. This approach was utilized to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a89b5cd6d49c9ce17c2d46396e91b9
Publikováno v:
European Journal of Organic Chemistry. 2016:150-157
A generalized method for accessing highly functionalized amino-substituted bicyclo[2.2.2]octanes via p-dodecylphenylsulfonamide catalyst in a good enantio- and diastereoselective fashion has been developed. A discussion of the mechanistic underpinnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f84755f9caaa2d22a4618d3e330a4bd
https://doi.org/10.1002/ejoc.201501302
https://doi.org/10.1002/ejoc.201501302
Autor:
Daniel S. Sem, Matthew Flister, Mohamed F. El-Mansy, Sergey V. Lindeman, William A. Donaldson, Kelsey Kalous
Publikováno v:
Chemistry - A European Journal. 21:10886-10895
A series of eight stereoisomeric N-(tetrahydroxy bicyclo-[5.1.0]oct-2S*-yl)phthalimides were prepared in one to four steps from N-(bicyclo[5.1.0]octa-3,5-dien-2-yl)phthalimide (±)-7, which is readily available from cyclooctatetraene (62 % yield). Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8e5046e5807b8063f192868051087b
https://doi.org/10.1002/chem.201501274
https://doi.org/10.1002/chem.201501274