Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mohamed Edfawy"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Autism spectrum disorders (ASDs) are known to present sex-specific differences. At the same time, understanding how maternal behaviours are affected by pathogenic mutations is crucial to translate research efforts since rearing may recursive
Externí odkaz:
https://doaj.org/article/5f9178e15f4c4dc9895d99f8a094741b
Autor:
Mohamed Edfawy, Joana R. Guedes, Marta I. Pereira, Mariana Laranjo, Mário J. Carvalho, Xian Gao, Pedro A. Ferreira, Gladys Caldeira, Lara O. Franco, Dongqing Wang, Ana Luisa Cardoso, Guoping Feng, Ana Luisa Carvalho, João Peça
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
GPRASP2 plays a role in trafficking of GPCRs and mutations in this gene have been linked to neurodevelopmental disorders. Here the authors study the role of Gprasp2 in the CNS and show that it regulates the surface availability of mGluR5 receptors an
Externí odkaz:
https://doaj.org/article/e34c7220e13b45b1be4e855d23adeb92
Autor:
Gladys L. Caldeira, R. P. Gouveia, Carlos A. V. Barreto, João Peça, Mohamed Edfawy, Ana Luísa Carvalho, Nuno Beltrão, A. S. Inacio, Joana R. Guedes, R. Macedo, B. Cruz, Susana R. Louros, Irina S. Moreira, Tiago Rondão, M. V. Rodrigues
Publikováno v:
Molecular Psychiatry. 27:2457-2469
Mutations linked to neurodevelopmental disorders, such as intellectual disability (ID), are frequently found in genes that encode for proteins of the excitatory synapse. Transmembrane AMPA receptor regulatory proteins (TARPs) are AMPA receptor auxili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b388ee4abf1d00e2ec4917aa9ca444
https://doi.org/10.1038/s41380-022-01487-w
https://doi.org/10.1038/s41380-022-01487-w
Autor:
João Peça, Mário Jorge da Silva Carvalho, Xian Gao, Pedro A. Ferreira, Ana L. Cardoso, Gladys L. Caldeira, Mariana Laranjo, Joana R. Guedes, Guoping Feng, Ana Luísa Carvalho, Dongqing Wang, Mohamed Edfawy, Marta I Pereira, Lara O. Franco
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications
Autism spectrum disorder (ASD) is characterized by dysfunction in social interactions, stereotypical behaviours and high co-morbidity with intellectual disability. A variety of syndromic and non-syndromic neurodevelopmental disorders have been connec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4173af7a4bb1055c835242dd2d888c4
http://link.springer.com/article/10.1038/s41467-019-09382-9
http://link.springer.com/article/10.1038/s41467-019-09382-9
Autor:
Renato Sousa, Mário Jorge da Silva Carvalho, João Peça, Catarina M. Seabra, Mohamed Edfawy, Lara O. Franco, Jéssica Costa, Joana R. Guedes, Ana L. Cardoso, Pedro A. Ferreira
Publikováno v:
Neuropsychopharmacology
Social hierarchies are present in most mammalian species. In nature, hierarchies offer a tradeoff between reduction of in-group fighting between males, at the expense of an asymmetric sharing of resources. Early life experiences and stress are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21fc3bf70e3a96d122c5d9831f097d4
https://pubmed.ncbi.nlm.nih.gov/32492699
https://pubmed.ncbi.nlm.nih.gov/32492699
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3056::2f80cda5a1038d500e09e2afb418d324
Publikováno v:
International journal of toxicology. 31(3)
The current study aimed at investigating the potential hepatoprotective property and mechanism of meloxicam (MEL) against carbon tetrachloride (CCl4)-induced hepatocellular damage in rats. Subcutaneous administration of CCl4 (2 mL/kg, twice/week for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068a55169ba575aa56c4f5a5caa8f17e
https://pubmed.ncbi.nlm.nih.gov/22556387
https://pubmed.ncbi.nlm.nih.gov/22556387
Publikováno v:
Toxicology and industrial health. 28(5)
The aim of the study was to evaluate the potential hepatoprotective utility of capsaicin against carbon tetrachloride (CCl4)-induced liver injury and to explore the possible mechanisms whereby this agent mediated its beneficial effects. We randomized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8538e578e2fc514d4cae775377faea6f
https://pubmed.ncbi.nlm.nih.gov/21859771
https://pubmed.ncbi.nlm.nih.gov/21859771
Maternal behaviours disrupted by Gprasp2 deletion modulate neurodevelopmental trajectory in progeny.
Autor:
Pereira, Marta I.1,2 (AUTHOR), Laranjo, Mariana1,3,4 (AUTHOR), Gomes, Marcos1,3,4 (AUTHOR), Edfawy, Mohamed1,3,5 (AUTHOR), Peça, João1,6 (AUTHOR) jpeca@cnc.uc.pt
Publikováno v:
Scientific Reports. 5/30/2024, Vol. 14 Issue 1, p1-15. 15p.
Publikováno v:
International Journal of Toxicology (Sage); May2012, Vol. 31 Issue 3, p276-286, 11p