Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Mohamed D H Hassona"'
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Akademický článek
Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis.
Autor: Mohammad T Elnakish, Mohamed D H Hassona, Mazin A Alhaj, Leni Moldovan, Paul M L Janssen, Mahmood Khan, Hamdy H Hassanain
Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42500 (2012)
The pathways inducing the critical transition from compensated hypertrophy to cardiac dilation and failure remain poorly understood. The goal of our study is to determine the role of Rac-induced signaling in this transition process. Our previous resu
Externí odkaz: https://doaj.org/article/ea38a26efa12406a9c86da1d46a7d7a6
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2
Vascular hypertrophy-associated hypertension of profilin1 transgenic mouse model leads to functional remodeling of peripheral arteries
Autor: Zeinb A. Abouelnaga, Mohammad T. Elnakish, Hamdy H. Hassanain, Mohamed D. H. Hassona, Pascal J. Goldschmidt-Clermont, Mazin A. Alhaj, Mohamed M Awad
Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 298:H2112-H2120
Increased mechanical stress/hypertension in the vessel wall triggers the hypertrophic signaling pathway, resulting in structural remodeling of vasculature. Vascular hypertrophy of resistance vessels leads to reduced compliance and elevation of blood
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4089ff2e6cfd0ac8cec50b4a309d96b
https://doi.org/10.1152/ajpheart.00016.2010
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3
Abstract 107: Mechanism of anticancer activity of BPS-001 (lyophilized leech saliva extract)
Autor: Amr Ammar, Abbas Mohammad Ghawi, Omer Kucuk, Abdualrahman Mohammed Abdualkader, Emma S. Tomlinson Guns, Mohamed Alaama, A. B. M. Helal Uddin, Mohamed D. H. Hassona
Publikováno v: Cancer Research. 77:107-107
Recent studies, investigating the composition and therapeutic potential of leech saliva have identified many peptides and proteins with multiple therapeutic properties including anti-thrombotic, antimicrobial and anti-metastatic. In vitro anti-cancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f12b8d0bac488e62d0aaf17a68c7940
https://doi.org/10.1158/1538-7445.am2017-107
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7
The effect of selective antihypertensive drugs on the vascular remodeling-associated hypertension: insights from a profilin1 transgenic mouse model
Autor: Altaf A. Wani, Zeinb A. Abouelnaga, Mazin A. Alhaj, Hamdy H. Hassanain, Mohammad T. Elnakish, Mohamed D. H. Hassona
Publikováno v: Journal of cardiovascular pharmacology. 57(5)
Hypertension represents a major risk factor for cardiovascular diseases. We have developed a novel transgenic mouse model by overexpressing the cDNA of human profilin1 in the blood vessels of transgenic mice, which led to vascular hypertrophy and hyp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4efe95aebae526d40860ddc697f3ba
https://pubmed.ncbi.nlm.nih.gov/21326111
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