The Editorial Position on ‘Recent Advances in Multifunctional Antimicrobial Peptides as Preclinical Therapeutic Studies and Clinical Future Applications’

Autor: Francesco Scavello, Mohamed Amiche, Jean-Eric Ghia

Publikováno v: Pharmaceutics, Vol 15, Iss 10, p 2383 (2023)

Antibiotic resistance has recently been recognized as an alarming issue and one of the leading causes of death worldwide [...]

Externí odkaz: https://doaj.org/article/9b061816f92c4b9c92122512469f1819

Enhanced Antibacterial Activity of Dermaseptin through Its Immobilization on Alginate Nanoparticles—Effects of Menthol and Lactic Acid on Its Potentialization

Autor: Noura Hazime, Yanath Belguesmia, Alexandre Barras, Mohamed Amiche, Rabah Boukherroub, Djamel Drider

Publikováno v: Antibiotics, Vol 11, Iss 6, p 787 (2022)

Dermaseptin B2 (DRS-B2) is an antimicrobial peptide secreted by Phyllomedusa bicolor, which is an Amazonian tree frog. Here, we show that the adsorption of DRS-B2 on alginate nanoparticles (Alg NPs) results in a formulation (Alg NPs + DRS-B2) with a

Externí odkaz: https://doaj.org/article/c23a315e3adf40a6ab0ddd60976c17d6

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans.

Autor: Célia Dos Santos, Sabah Hamadat, Karen Le Saux, Clara Newton, Meriem Mazouni, Loussiné Zargarian, Mickael Miro-Padovani, Patricia Zadigue, Jean Delbé, Yamina Hamma-Kourbali, Mohamed Amiche

Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0182926 (2017)

Dermaseptin-B2 (DRS-B2) is a multifunctional cationic antimicrobial peptide (CAP) isolated from frog skin secretion. We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we

Externí odkaz: https://doaj.org/article/3b02bf40888a4211bad00eaf50f6d847

Dermaseptins, Multifunctional Antimicrobial Peptides: A Review of Their Pharmacology, Effectivity, Mechanism of Action, and Possible Future Directions

Autor: Douwe Dekker, Mohamed Amiche, Emiel Jacob Henri Bartels

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Frontiers, 2019, 10, pp.1421. ⟨10.3389/fphar.2019.01421⟩
Frontiers in Pharmacology, Vol 10 (2019)

Peptides produced by animals could be an inspiration for biopharmaceutical drugs. Dermaseptins, multifunctional antimicrobial peptides, isolated from the Amazonian tree-frog of Phyllomedusa genus, are a group of α-helical shaped polycationic peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5b2b7c9aaf05a92efd671650a09e73
https://hal.archives-ouvertes.fr/hal-02381539/document

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

Autor: Mohamed Amiche, Patricia Zadigue, Jean Delbé, Loussiné Zargarian, Clara Newton, Yamina Hamma-Kourbali, Mickael Miro-Padovani, Karen Le Saux, Meriem Mazouni, Célia Dos Santos, Sabah Hamadat

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, Vol 12, Iss 8, p e0182926 (2017)
PLoS ONE

Dermaseptin-B2 (DRS-B2) is a multifunctional cationic antimicrobial peptide (CAP) isolated from frog skin secretion. We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f414675995572ef1c7cc9b09ecdefd
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0182926