C-Terminal Amidation of Chlorotoxin Does Not Affect Tumour Cell Proliferation and Has No Effect on Toxin Cytotoxicity

Autor: Mohamed A. Abdel-Rahman, Zohour I. Nabil, Aya S. Ayed, Mohamed Alaa A. Omran, Kirsti A. Newton, Peter Strong

Publikováno v: International Journal of Peptide Research and Therapeutics. 27:659-667

Chlorotoxin (Cltx), a cell-penetrating peptide from the venom of the scorpion Leiurus quinquestriatus has selective activity on a range of neuroectodermal tumours and related cell lines. Although the precise mechanism of Cltx action is not clear, Clt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8eb0e7a6bd00f2758d2677bdb7961a3
https://doi.org/10.1007/s10989-020-10117-4

TOXIN EVOLUTION IN SCORPION VENOM: EVIDENCE FOR TOXIN DIVERGENCE UNDER STRONG NEGATIVE SELECTION INLEIURUS QUINQUESTRIATUSSUBSPECIES

Autor: Patrick J. Hussey, Andrei Smertenko, Mohamed Alaa A. Omran, Alistair McVean

Publikováno v: Journal of Toxicology: Toxin Reviews. 20:229-244

The Buthid scorpion Leiurus quinquestriatus is divided into two sub-species whose region of contact occurs at the Suez Isthmus. L.q. quinquestriatus, found in the North Africa is distinguished from L.q. hebraeus by minor differences in morphology. De

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae8441e359f1aab20d34a61831647401
https://doi.org/10.1081/txr-100108558

Extraction and phytochemical investigation of Calotropis procera: effect of plant extracts on the activity of diverse muscles

Autor: Zohour I. Nabil, Amal M. Youssef Moustafa, Mohamed Alaa A. Omran, S. H. Ahmed, Aida A. Hussein

Publikováno v: Pharmaceutical biology. 48(10)

Calotropis procera (Ait.) R.Br. (Asclepiadaceae) is a shrub or small tree that grows wild in Egypt. Calotropis acts as a purgative, anthelmintic, anticoagulant, palliative (in problems with respiration, blood pressure), antipyretic, and analgesic, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6cc3b075bea502b36ac570e47020a0
https://pubmed.ncbi.nlm.nih.gov/20690894

Biochemical and morphological analysis of cell death induced by Egyptian cobra (Naja haje) venom on cultured cells

Autor: Mohamed Alaa A. Omran, George Dickson, Stewart A. Fabb

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 10, Issue: 3, Pages: 219-241, Published: 2004
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 10, Iss 3, Pp 219-241 (2004)
Journal of Venomous Animals and Toxins including Tropical Diseases v.10 n.3 2004
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP

We investigated the in vitro process of cell death caused by Egyptian cobra venom on primary human embryonic kidney (293T) and mouse myoblast (C2C12) cell lines. The aim of these studies was to provide further information about triggering cell death,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83649c3db1c44591db0ee5d5a543611
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992004000300004&lng=en&tlng=en

Changes in the arterial blood pressure, heart rate and normal ECG parameters of rat after envenomation with Egyptian cobra (Naja haje) venom

Autor: Ismail M. Abdel-Nabi, Mohamed Alaa A. Omran

Publikováno v: Humanexperimental toxicology. 16(6)

1 The effect of Egyptian cobra (Naja haje) venom on the normal electrical activity of the cardiac muscles (ECG) and arterial blood pressure of envenomated rats were investigated in this study. 2 Rats were divided into three groups. The first group wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159f97dc10fca95135819beb4d7e1e29
https://pubmed.ncbi.nlm.nih.gov/9219029