Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mohamed Abou El Hassan"'
Autor:
Mohamed Abou El Hassan, Katherine Huang, Manoja B K Eswara, Michael Zhao, Lan Song, Tao Yu, Yu Liu, Jeffrey C Liu, Sean McCurdy, Anqi Ma, Joan Wither, Jian Jin, Eldad Zacksenhaus, Jeffrey L Wrana, Rod Bremner
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0126466 (2015)
Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator induced in many cancers. It is thought to drive tumorigenesis by repressing division, stemness, and/or developmental regulators. Cancers evade immune detection, and diverse immune regula
Externí odkaz:
https://doaj.org/article/deb2dbf67a804f41b647a9f6ee0bd3a6
Publikováno v:
BioTechniques, Vol 55, Iss 4, Pp 204-206 (2013)
Tools for studying replication fork dynamics are critical for dissecting the mechanisms of DNA replication, DNA repair, histone deposition, and epigenetic memory. Isolation of protein on nascent DNA (iPOND) is an elegant method for purifying replicat
Externí odkaz:
https://doaj.org/article/afe48e01fcd54ba8ae4ef04d59126aea
Autor:
Philipp Knopf, Manal O. Elnenaei, Mohamed Abou El Hassan, Julie Wagner, Shashi Gujar, Daniel Gaston, Barry E. Kennedy, Jeanette E. Boudreau, Clinton J. V. Campbell, Samuel D. Cutler, Andrea J. Thoni, Nicholas A. Forward, Darrell White, Marissa Goudie
Publikováno v:
The Journal of Molecular Diagnostics. 23:1699-1714
Multiple myeloma presents with numerous primary genomic lesions that broadly dichotomize cases into hyperdiploidy or IgH translocated. Clinically, these large alterations are assessed by fluorescence in situ hybridization (FISH) for risk stratificati
Publikováno v:
Clinical Biochemistry. 93:99-103
Background Immunoassays provide a rapid tool for the screening of drugs-of-abuse (DOA). However, results are presumptive and confirmatory testing is warranted. To reduce associated cost and delay, laboratories should employ assays with high positive
Autor:
Samuel D, Cutler, Philipp, Knopf, Clinton J V, Campbell, Andrea, Thoni, Mohamed, Abou El Hassan, Nicholas, Forward, Darrell, White, Julie, Wagner, Marissa, Goudie, Jeanette E, Boudreau, Barry E, Kennedy, Shashi, Gujar, Daniel, Gaston, Manal O, Elnenaei
Publikováno v:
The Journal of molecular diagnostics : JMD. 23(12)
Multiple myeloma presents with numerous primary genomic lesions that broadly dichotomize cases into hyperdiploidy or IgH translocated. Clinically, these large alterations are assessed by fluorescence in situ hybridization (FISH) for risk stratificati
Autor:
Edward Randell, Yanping Gong, Kent Dooley, Vilte E. Barakauskas, Peter Catomeris, Jason L. Robinson, Mohamed Abou El Hassan, Julie L.V. Shaw, Nicole White-Al Habeeb, Jennifer Taher, Lori A. Beach, Vathany Kulasingam, Dana Bailey, Ivan M. Blasutig, Danijela Konforte, Paul M. Yip, Peter A. Kavsak
Publikováno v:
Clinical Biochemistry
Highlights • SARS-CoV-2 serology offers limited clinical utility for individuals. • SARS-CoV-2 serology may be useful for seroprevalence studies. • Claims regarding protective immunity or infectivity cannot be made using serology. • Assay cli
Publikováno v:
Critical Reviews in Clinical Laboratory Sciences. 55:516-534
Diurnal rhythm complicates the acquisition of clinical laboratory samples by adding a predictable time-dependent component to the pre-analytical variation that, if not taken into account, degrades ...
Autor:
Mohamed Abou El Hassan, Wenda L. Greer, Nicholas A. Forward, Clinton J. V. Campbell, Samuel D. Cutler, Philipp Knopf, Manal O. Elnenaei, Julie Wagner, Daniel Gaston, Darrell White, Keaton Sinclair, Stephen Couban, Marissa Goudie
Publikováno v:
Clinical genetics. 96(2)
Multiple myeloma (MM) is an incurable hematological malignancy that relies on cytogenetic determination of copy number abnormalities (CNAs) for prognosis and management. Low-depth whole genome sequencing (LD-WGS) is a cost-effective alternative to ta
Publikováno v:
The Journal of biological chemistry. 293(26)
Transcriptional activators bind DNA and recruit cofactors to modify chromatin. The extent to which these two events are separable is unclear. Here, using a custom ChIP tiling array to map chromatin modifications, we show that interferon-γ-induced DN
Publikováno v:
The Journal of Immunology. 194:5007-5013
CIITA (or MHC2TA) coordinates constitutive and IFN-γ–induced expression of MHC class II genes. IFN-γ responsiveness of CIITA requires BRG1 (SMARCA4), the ATPase engine of the chromatin remodeling SWI/SNF complex (also called BAF). SWI/SNF is defe