Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mohamed Abdelmaboud Sobhy"'
Autor:
Vlad-Stefan Raducanu, Alfredo De Biasio, Souvika Bakshi, Ramon Crehuet, Masateru Takahashi, Matthew Percival, Samir M. Hamdan, Timothy J. Ragan, Frederick W. Muskett, Mohamed Abdelmaboud Sobhy, Muhammad Tehseen, Claudia Lancey, Kerry Blair
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Y-family DNA polymerase κ (Pol κ) can replicate damaged DNA templates to rescue stalled replication forks. Access of Pol κ to DNA damage sites is facilitated by its interaction with the processivity clamp PCNA and is regulated by PCNA mono-ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c8329d6696675e9fca9f1a4038b024
https://doaj.org/article/fcb4f0fc2e6645adb3f4b1e3da3263f8
https://doaj.org/article/fcb4f0fc2e6645adb3f4b1e3da3263f8
Autor:
Sara Mfarrej, Anwar M. Hashem, Afrah Alsomali, Asim Khogeer, Kosuke Sakashita, Fadwa S. Alofi, Takahiro Kusakabe, Hiroaki Mon, Mohamed Abdelmaboud Sobhy, Sharif Hala, Arnab Pain, Muhammad Tehseen, Samir M. Hamdan, Masateru Takahashi, Fatimah S. Alhamlan, Rahul Salunke, Gerardo Ramos Mandujano, Mo Li, Jae Man Lee, Ahmed A. Al-Qahtani, Naif A.M. Almontashiri, Etsuko Takahashi
One-step RT-qPCR is the most widely applied method for COVID-19 diagnostics. Designing in-house one-step RT-qPCR kits is restricted by the patent-rights for the production of enzymes and the lack of information about the components of the commercial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830fa410fdcab2fc35f38095d50e1063
Autor:
Ramon Crehuet, Claudia Lancey, Muhammad Tehseen, Samir M. Hamdan, Timothy J. Ragan, Masateru Takahashi, Mohamed Abdelmaboud Sobhy, Alfredo De Biasio
Replacement of the stalled replicative polymerase (Pol δ) at a DNA lesion by the error-prone DNA polymerase κ (Pol κ) restarts synthesis past the lesion to prevent genome instability. The switching from Pol δ to Pol κ is mediated by the processi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c21b85d37d8150796d31729cb5379f7
https://doi.org/10.1101/2020.07.10.196956
https://doi.org/10.1101/2020.07.10.196956
Autor:
Ulrich Stingl, Intikhab Alam, Jasmeen S. Merzaban, Etsuko Takahashi, Anastassja Akal, Luay I. Joudeh, Gobind Das, Samir M. Hamdan, Enzo Di Fabrizio, Muhammad Tehseen, Mohamed Abdelmaboud Sobhy, Masateru Takahashi, Mohamed M. Elshenawy, Monica Marini, Kosuke Sakashita
Publikováno v:
The FASEB Journal
The deep-sea brines of the Red Sea are remote and unexplored environments characterized by high temperatures, anoxic water, and elevated concentrations of salt and heavy metals. This environment provides a rare system to study the interplay between h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49fbb7b69907bace5241b487c558425
http://europepmc.org/articles/PMC6051491
http://europepmc.org/articles/PMC6051491
Autor:
Samir M. Hamdan, Amer Bralic, Fahad Rashid, Vlad-Stefan Raducanu, Muhammad Tehseen, Mohamed Abdelmaboud Sobhy, Yujing Ouyang, Manal S. Zaher, Masateru Takahashi
Publikováno v:
Journal of Visualized Experiments.
Bulk methods measure the ensemble behavior of molecules, in which individual reaction rates of the underlying steps are averaged throughout the population. Single-molecule Förster resonance energy transfer (smFRET) provides a recording of the confor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb27a422be41b9c596cf939b17e0cba
https://doi.org/10.3791/60045
https://doi.org/10.3791/60045
Autor:
Masateru Takahashi, Samir M. Hamdan, Muhammad Tehseen, Amer Bralic, Fahad Rashid, Vlad-Stefan Raducanu, Manal S. Zaher, Mohamed Abdelmaboud Sobhy
Publikováno v:
Nucleic Acids Research
Human GEN1 is a cytosolic homologous recombination protein that resolves persisting four-way Holliday junctions (HJ) after the dissolution of the nuclear membrane. GEN1 dimerization has been suggested to play key role in the resolution of the HJ, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9252e6e5d640f9157efb1768ad4b6cb
https://pubmed.ncbi.nlm.nih.gov/30590761
https://pubmed.ncbi.nlm.nih.gov/30590761
Autor:
Samir M. Hamdan, Luay I. Joudeh, Manal S. Zaher, Bo Song, Muhammad Tehseen, Fahad Rashid, Manju M. Hingorani, Mohamed Abdelmaboud Sobhy
Publikováno v:
Nucleic Acids Research
RNA–DNA hybrid primers synthesized by low fidelity DNA polymerase α to initiate eukaryotic lagging strand synthesis must be removed efficiently during Okazaki fragment (OF) maturation to complete DNA replication. In this process, each OF primer is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c849240aef573848f5fc043286e3d7
Autor:
Dalaver H. Anjum, Samir M. Hamdan, Ali Reza Behzad, Rachid Sougrat, Fahad Rashid, Mohamed Abdelmaboud Sobhy
Publikováno v:
Microscopy and Microanalysis. 25:1014-1015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200c38371257864cc726d0071f02e66e
https://doi.org/10.1017/s1431927619005804
https://doi.org/10.1017/s1431927619005804
Autor:
Samir M. Hamdan, Mohamed M. Elshenawy, Aaron J. Oakley, Masateru Takahashi, Slobodan Jergic, Nicholas E. Dixon, Zhi-Qiang Xu, Mohamed Abdelmaboud Sobhy
Publikováno v:
Nature. 525:394-398
In all domains of life, DNA synthesis occurs bidirectionally from replication origins. Despite variable rates of replication fork progression, fork convergence often occurs at specific sites. Escherichia coli sets a 'replication fork trap' that allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0acb761453f7c19d31987ee25de959
https://doi.org/10.1038/nature14866
https://doi.org/10.1038/nature14866
Autor:
Ivaylo Ivanov, Samir M. Hamdan, Hubert Marek Piwonski, Chunli Yan, John A. Tainer, Satoshi Habuchi, Mohamed Abdelmaboud Sobhy, Paul D. Harris, Luay I. Joudeh, Fahad Rashid, Susan E. Tsutakawa, Manal S. Zaher
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Human flap endonuclease 1 (FEN1) and related structure-specific 5’nucleases precisely identify and incise aberrant DNA structures during replication, repair and recombination to avoid genomic instability. Yet, it is unclear how the 5’nuclease mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e3f06bf0b1b0751532ecce92783791
https://doi.org/10.7554/elife.21884
https://doi.org/10.7554/elife.21884