Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Mohamed A. Mughal"'
Autor:
Jeong Seon Yoon, Jong-Hwan Lee, Tae Gen Son, Mohamed R. Mughal, Nigel H. Greig, Mark P. Mattson
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 3, Pp 624-629 (2011)
Pregabalin, a Ca2+ channel α2δ-subunit antagonist with analgesic and antiepileptic activity, reduced neuronal loss and improved functional outcome in a mouse model of focal ischemic stroke. Pregabalin administration (5–10 mg/kg, i.p.) 30–90 min
Externí odkaz:
https://doaj.org/article/51759cfcb39b4299a8a225b0c42389e1
Autor:
Sic L. Chan, Amin Yu, Jogi V. Pattisapu, Yoonsuk Cho, Dong-Gyu Jo, Srinivasulu Chigurupati, Seung Hyun Baek, Mark P. Mattson, Jinsu Park, Mohamed R Mughal, Meenu Madan
Publikováno v:
J Gerontol A Biol Sci Med Sci
The accumulation of amyloid-β (Aβ) is a characteristic event in the pathogenesis of Alzheimer’s disease (AD). Aquaporin 1 (AQP1) is a membrane water channel protein belonging to the AQP family. AQP1 levels are elevated in the cerebral cortex duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d9511c5e0c5869cec271b82f569ea5
https://europepmc.org/articles/PMC7756701/
https://europepmc.org/articles/PMC7756701/
Autor:
Eitan Okun, Boaz Barak, Ravit Saada-Madar, Sarah M Rothman, Kathleen J Griffioen, Nicholas Roberts, Kamilah Castro, Mohamed R Mughal, Mario A Pita, Alexis M Stranahan, Thiruma V Arumugam, Mark P Mattson
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47522 (2012)
Toll-like receptors (TLRs) play essential roles in innate immunity and increasing evidence indicates that these receptors are expressed in neurons, astrocytes and microglia in the brain where they mediate responses to infection, stress and injury. Ve
Externí odkaz:
https://doaj.org/article/4afce1071bb444bc9788cf6b7f464638
Autor:
Rebecca Casaday Potts, Peisu Zhang, Andrea L Wurster, Patricia Precht, Mohamed R Mughal, William H Wood, Yonqing Zhang, Kevin G Becker, Mark P Mattson, Michael J Pazin
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24515 (2011)
CHD5 is frequently deleted in neuroblastoma and is a tumor suppressor gene. However, little is known about the role of CHD5 other than it is homologous to chromatin remodeling ATPases. We found CHD5 mRNA was restricted to the brain; by contrast, most
Externí odkaz:
https://doaj.org/article/b6dc22d1f8ee429592a1873421761779
Autor:
Srinivasulu Chigurupati, Mohamed R Mughal, Sic L Chan, Thiruma V Arumugam, Akanksha Baharani, Sung-Chun Tang, Qian-Sheng Yu, Harold W Holloway, Ross Wheeler, Suresh Poosala, Nigel H Greig, Mark P Mattson
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10044 (2010)
Wound healing is a complex process involving intrinsic dermal and epidermal cells, and infiltrating macrophages and leukocytes. Excessive oxidative stress and associated inflammatory processes can impair wound healing, and antioxidants have been repo
Externí odkaz:
https://doaj.org/article/b74c5a2aed3646e7a3fc157c369f2cb9
Autor:
Karine Loulier, Justin D Lathia, Veronique Marthiens, Jenne Relucio, Mohamed R Mughal, Sung-Chun Tang, Turhan Coksaygan, Peter E Hall, Srinivasulu Chigurupati, Bruce Patton, Holly Colognato, Mahendra S Rao, Mark P Mattson, Tarik F Haydar, Charles Ffrench-Constant
Publikováno v:
PLoS Biology, Vol 7, Iss 8, p e1000176 (2009)
During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zone (VZ) lining the cerebral ventricles. They exhibit apical and basal processes that contact the ventricular surface and the pial bas
Externí odkaz:
https://doaj.org/article/5f881e0fdd104c3eb873539ae22afc01
Autor:
Srinivasulu Chigurupati, Thiruma V Arumugam, Tae Gen Son, Justin D Lathia, Shafaq Jameel, Mohamed R Mughal, Sung-Chun Tang, Dong-Gyu Jo, Simonetta Camandola, Marialuisa Giunta, Irina Rakova, Nazli McDonnell, Lucio Miele, Mark P Mattson, Suresh Poosala
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1167 (2007)
The Notch signaling pathway is critically involved in cell fate decisions during development of many tissues and organs. In the present study we employed in vivo and cell culture models to elucidate the role of Notch signaling in wound healing. The h
Externí odkaz:
https://doaj.org/article/e7d37e8a71c04d1f868f9dc864698035
Publikováno v:
INTED2019 Proceedings.
Publikováno v:
Archives of disease in childhood. Fetal and neonatal edition. 104(5)
Metabolic bone disease of prematurity (MBDP) is characterised by skeletal demineralisation, and in severe cases it can result in fragility fractures of long bones and ribs during routine handling. MBDP arises from prenatal and postnatal factors. Infa
Autor:
Omri Snir, Gad Lavie, Jie Wan Kim, Jun Ho Lee, Mark P. Mattson, Ana Lustig, Mohamed R. Mughal, Arnell Carter, Meital Halperin-Sheinfeld, Hyun Jin Tae, Eitan Okun, Dennis D. Taub, Benjamin Sredni, Dolgar Baatar
Publikováno v:
NeuroMolecular Medicine. 16:292-307
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) involving demyelinating and neurodegenerative processes. Several of the major pathological CNS alterations and behavioral deficits of MS are recapitulat