Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mohamed, Hagras"'
Publikováno v:
The Egyptian Journal of Internal Medicine, Vol 36, Iss 1, Pp 1-8 (2024)
Abstract Background Smoking is a major preventable risk factor for cardiovascular morbidity and mortality. Tobacco smoking induces atherosclerosis, ischemic heart diseases, and arrhythmias. The impact of electronic cigarettes on cardiovascular health
Externí odkaz:
https://doaj.org/article/980a38b9873a4d48841d1c8cebeeef7b
Autor:
Ibrahim H. Eissa, Hazem Elkady, Mahmoud Rashed, Alaa Elwan, Mohamed Hagras, Mohammed A. Dahab, Mohammed S. Taghour, Ibrahim M. Ibrahim, Dalal Z. Husein, Eslam B. Elkaeed, Hanan A. Al-ghulikah, Ahmed M. Metwaly, Hazem A. Mahdy
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24005- (2024)
In this study, a series of seven novel 2,4-dioxothiazolidine derivatives with potential anticancer and VEGFR-2 inhibiting abilities were designed and synthesized as VEGFR-2 inhibitors. The synthesized compounds were tested in vitro for their potentia
Externí odkaz:
https://doaj.org/article/941a6ba96f1444fc9f1952738aba1c7c
Autor:
Mohamed Hagras, Marwa A. Saleh, Rogy R. Ezz Eldin, Abdelrahman A. Abuelkhir, Emad Gamil Khidr, Ahmed A. El-Husseiny, Hesham A. El-Mahdy, Eslam B. Elkaeed, Ibrahim H. Eissa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 386-402 (2022)
In the current work, some 1,3,4-oxadiazole-naphthalene hybrids were designed and synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for their antiproliferative activity against two human cancer cell lines namely, Hep
Externí odkaz:
https://doaj.org/article/428f05a2945c4f5b90792359899b4312
Autor:
Asmaa A. Mandour, Ibrahim F. Nassar, Mohammed T. Abdel Aal, Mahmoud A. E. Shahin, Wael A. El-Sayed, Maghawry Hegazy, Amr Mohamed Yehia, Ahmed Ismail, Mohamed Hagras, Eslam B. Elkaeed, Hanan M. Refaat, Nasser S. M. Ismail
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1957-1973 (2022)
Cyclin-dependent kinase inhibition is considered a promising target for cancer treatment for its crucial role in cell cycle regulation. Pyrazolo pyrimidine derivatives were well established for their antitumor activity via CDK2 inhibition. In this re
Externí odkaz:
https://doaj.org/article/1e6ab14dd8874e4886ee7d210668ea2f
Autor:
Heba S. A. Elzahabi, Eman S. Nossier, Rania A. Alasfoury, May El-Manawaty, Sara M. Sayed, Eslam B. Elkaeed, Ahmed M. Metwaly, Mohamed Hagras, Ibrahim H. Eissa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1053-1076 (2022)
A new series of pyrido[2,3-d]pyrimidin-4(3H)-one derivatives having the essential pharmacophoric features of EGFR inhibitors has been designed and synthesised. Cell viability screening was performed for these compounds against A-549, PC-3, HCT-116, a
Externí odkaz:
https://doaj.org/article/043a1c62528a44f39d1f4e0955ba4c9b
Autor:
Ahmed Fayez Ghaith, Mohamed Hasan Radwan, Mohamed Rashed Taha, Mohamed Ahmed Elbendary, Mahmoud Elsayed Al Damhogy, Ayman Mohamed Hagras
Publikováno v:
Archivio Italiano di Urologia e Andrologia, Vol 94, Iss 4 (2022)
Objectives: The aim of this study was to assess changes in quality of life and pain alleviation in women with refractory Interstitial Cystitis/Painful Bladder syndrome following a combined intravesical injection of Botulinum Toxin-A and Hyaluronic Ac
Externí odkaz:
https://doaj.org/article/9dfce8688ddc481083f4cdad2e862e5a
Autor:
Khaled Mohamed Almekaty, Mohamed Hasan Zahran, Mohamed Lotfy Amer, Ayman Mohamed Hagras, Khaled Abdelaziz Salem, Ayman Sayed Rashed, Ahmed Fayez Ghaith
Publikováno v:
Archivio Italiano di Urologia e Andrologia, Vol 94, Iss 3 (2022)
Objectives: To report on the live birth rates (LBRs) following percutaneous epididymal sperm aspiration (PESA) in men with obstructive azoospermia (OA) and factors affecting treatment outcome which is under reported in the literature. Methods: This i
Externí odkaz:
https://doaj.org/article/a8f42f768c40475c8b94eba10a0dbab5
Autor:
Omnia R. Elbatrawy, Mohamed Hagras, Moshira A. El Deeb, Fatimah Agili, Maghawry Hegazy, Ahmed A. El-Husseiny, Mahmoud Mohamed Mokhtar, Samy Y. Elkhawaga, Ibrahim H. Eissa, Samar El-Kalyoubi
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 966 (2023)
Background: Histone deacetylase inhibitors (HDACIs) are a relatively new class of potential drugs for treating cancer. Aim: Discovery of new anticancer agents targeting HDAC. Methods: New uracil and thiouracil derivatives panels were designed and syn
Externí odkaz:
https://doaj.org/article/aaf9f96a1e06487090579a384e6ac32f
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract Background The heterocyclic compounds particularly pyridine displayed clinical and biological implementation. Pyridine scaffolds have been detected in most relevant drug molecules that included pyridine provided a great possibility for treat
Externí odkaz:
https://doaj.org/article/11343823743540ac910a7749e4b3f1ab
Autor:
Mohamed Hagras, Moshira A. El Deeb, Heba S. A. Elzahabi, Eslam B. Elkaeed, Ahmed B. M. Mehany, Ibrahim H. Eissa
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 640-658 (2021)
Discovering of new anticancer agents with potential activity against tubulin polymerisation is still a promising approach. Colchicine binding site inhibitors are the most relevant anti-tubulin polymerisation agents. Thus, new quinoline derivatives ha
Externí odkaz:
https://doaj.org/article/1b5aa93b573e4bc2a093e3d51380f374