Assessment of Landslide Risks Through a Multi-Disciplinary Approach: A Case Study of Al Hoceima, Northern Morocco

Autor: Mohamed El Khattabi, Jamal El Khattabi, Ali Azdimousa, Pierre Plotto, Gharibi El Khadir

Publikováno v: Journal of Disaster Research. 18:424-435

Landslides are very dangerous phenomena dependent upon several parameters and criteria widespread in Northern Morocco. Their management is complex because of the dangers posed to the population and by the habitat, but also due to the difficulty of re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a2dd96ed5bd409fc167861b8c94195b
https://doi.org/10.20965/jdr.2023.p0424

Data from Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies

Autor: Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe

Bone morphogenetic proteins (BMP) have important but distinct roles in tissue homeostasis and disease, including carcinogenesis and tumor progression. A large number of BMP inhibitors are available to study BMP function; however, as most of these ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10d83c17fc91e5e3adde4774a0324064
https://doi.org/10.1158/1535-7163.c.6536857.v1

Table S1 from Effective Inhibition of Bone Morphogenetic Protein Function by Highly Specific Llama-Derived Antibodies

Autor: Kausilia K. Krishnadath, Hergen Spits, Jan Paul Medema, C. Theo Verrips, Edward Dolk, Cheryl Zimberlin, Lucy Rutten, Mohamed El Khattabi, Koen Wagner, Silvia Calpe

Summary of epitope binning experiments of the VHHs and controls

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d561ed6d3a9847aeff23646344834
https://doi.org/10.1158/1535-7163.22501657.v1

A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition.

Autor: David Lutje Hulsik, Ying-ying Liu, Nika M Strokappe, Simone Battella, Mohamed El Khattabi, Laura E McCoy, Charles Sabin, Andreas Hinz, Miriam Hock, Pauline Macheboeuf, Alexandre M J J Bonvin, Johannes P M Langedijk, David Davis, Anna Forsman Quigley, Marlén M I Aasa-Chapman, Michael S Seaman, Alejandra Ramos, Pascal Poignard, Adrien Favier, Jean-Pierre Simorre, Robin A Weiss, C Theo Verrips, Winfried Weissenhorn, Lucy Rutten

Publikováno v: PLoS Pathogens, Vol 9, Iss 3, p e1003202 (2013)

The membrane proximal external region (MPER) of the HIV-1 glycoprotein gp41 is targeted by the broadly neutralizing antibodies 2F5 and 4E10. To date, no immunization regimen in animals or humans has produced HIV-1 neutralizing MPER-specific antibodie

Externí odkaz: https://doaj.org/article/bedacc53dae644739bdc70b2ea981c66

Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights

Autor: Eleanor R, Gray, Jennifer C, Brookes, Christophe, Caillat, Valérian, Turbé, Benjamin L J, Webb, Luke A, Granger, Benjamin S, Miller, Laura E, McCoy, Mohamed, El Khattabi, C Theo, Verrips, Robin A, Weiss, Dorothy M, Duffy, Winfried, Weissenhorn, Rachel A, McKendry

Publikováno v: ACS Infectious Diseases
ACS Infectious Diseases, 2017, ⟨10.1021/acsinfecdis.6b00189⟩
ACS Infectious Diseases, American Chemical Society, 2017, ⟨10.1021/acsinfecdis.6b00189⟩

International audience; Preventing the spread of infectious diseases remains an urgent priority worldwide, and this is driving the development of advanced nanotechnology to diagnose infections at the point of care. Herein, we report the creation of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5630792871cceb574d2be8bcb941599
https://hal.univ-grenoble-alpes.fr/hal-01561577