Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Mohamed, Chami"'
Autor:
Kaili Chen, Adrian Najer, Patrick Charchar, Catherine Saunders, Chalaisorn Thanapongpibul, Anna Klöckner, Mohamed Chami, David J. Peeler, Inês Silva, Luca Panariello, Kersti Karu, Colleen N. Loynachan, Leah C. Frenette, Michael Potter, John S. Tregoning, Ivan P. Parkin, Andrew M. Edwards, Thomas B. Clarke, Irene Yarovsky, Molly M. Stevens
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Staphylococcus aureus is a leading cause of nosocomial implant-associated infections, causing significant morbidity and mortality, underscoring the need for rapid, non-invasive, and cost-effective diagnostics. Here, we optimise the synthesis
Externí odkaz:
https://doaj.org/article/cce09cda3cc44bc1a4d83bbce5d35001
Autor:
Narges Seyfizadeh, David Kalbermatter, Thomas Imhof, Moritz Ries, Christian Müller, Leonie Jenner, Elisabeth Blumenschein, Alexandra Yendrzheyevskiy, Frank Grün, Kevin Moog, Daniel Eckert, Ronja Engel, Philipp Diebolder, Mohamed Chami, Jürgen Krauss, Torsten Schaller, Michaela Arndt
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-22 (2024)
Abstract Background Infections with Herpes simplex virus (HSV)-1 or -2 usually present as mild chronic recurrent disease, however in rare cases can result in life-threatening conditions with a large spectrum of pathology. Monoclonal antibody therapy
Externí odkaz:
https://doaj.org/article/90dc32068a724229a0d3541e5d8a5ec7
Autor:
Manish K. Yadav, Parishmita Sarma, Jagannath Maharana, Manisankar Ganguly, Sudha Mishra, Nashrah Zaidi, Annu Dalal, Vinay Singh, Sayantan Saha, Gargi Mahajan, Saloni Sharma, Mohamed Chami, Ramanuj Banerjee, Arun K. Shukla
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The Hydroxycarboxylic acid receptor 2 (HCA2), also known as the niacin receptor or GPR109A, is a prototypical GPCR that plays a central role in the inhibition of lipolytic and atherogenic activities. Its activation also results in vasodilati
Externí odkaz:
https://doaj.org/article/81a025e0280946b39508480f0e82854e
Autor:
Enja Tatjana Kipfer, David Hauser, Martin J Lett, Fabian Otte, Lorena Urda, Yuepeng Zhang, Christopher MR Lang, Mohamed Chami, Christian Mittelholzer, Thomas Klimkait
Publikováno v:
eLife, Vol 12 (2023)
Reverse genetic systems enable the engineering of RNA virus genomes and are instrumental in studying RNA virus biology. With the recent outbreak of the coronavirus disease 2019 pandemic, already established methods were challenged by the large genome
Externí odkaz:
https://doaj.org/article/54577bf2a8de47538fbd50df01e9ec39
Autor:
Valérie Biou, Ricardo Jorge Diogo Adaixo, Mohamed Chami, Pierre-Damien Coureux, Benoist Laurent, Véronique Yvette Ntsogo Enguéné, Gisele Cardoso de Amorim, Nadia Izadi-Pruneyre, Christian Malosse, Julia Chamot-Rooke, Henning Stahlberg, Philippe Delepelaire
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/c7af059ed5c746c0a2b73aef15023f62
Autor:
Valérie Biou, Ricardo Jorge Diogo Adaixo, Mohamed Chami, Pierre-Damien Coureux, Benoist Laurent, Véronique Yvette Ntsogo Enguéné, Gisele Cardoso de Amorim, Nadia Izadi-Pruneyre, Christian Malosse, Julia Chamot-Rooke, Henning Stahlberg, Philippe Delepelaire
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Cryo-EM structures of the ExbB and ExbB-ExbD membrane protein complexes in the Gram-negative bacteria Serratia marcescens reveal insights into inner membrane machinery and interactions specific to the Has system.
Externí odkaz:
https://doaj.org/article/c3d4aa894c984ee69a3fe045882230f3
Autor:
Mathieu Botte, Dongchun Ni, Stephan Schenck, Iwan Zimmermann, Mohamed Chami, Nicolas Bocquet, Pascal Egloff, Denis Bucher, Matilde Trabuco, Robert K. Y. Cheng, Janine D. Brunner, Markus A. Seeger, Henning Stahlberg, Michael Hennig
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Lateral opening of the LptDE transporter in the outer membrane of Gram-negative bacteria is necessary for insertion of lipopolysaccharides. Here, Botte et al. report a cryo-EM structure of a partially opened LptDE transporter, in complex with rigid c
Externí odkaz:
https://doaj.org/article/25e3d626c5e9434d8732b67049815a5b
Autor:
Lenka Horváthová, Vojtěch Žárský, Tomáš Pánek, Romain Derelle, Jan Pyrih, Alžběta Motyčková, Veronika Klápšťová, Martina Vinopalová, Lenka Marková, Luboš Voleman, Vladimír Klimeš, Markéta Petrů, Zuzana Vaitová, Ivan Čepička, Klára Hryzáková, Karel Harant, Michael W. Gray, Mohamed Chami, Ingrid Guilvout, Olivera Francetic, B. Franz Lang, Čestmír Vlček, Anastasios D. Tsaousis, Marek Eliáš, Pavel Doležal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Bacteria use the type 2 secretion system to secrete enzymes and toxins across the outer membrane to the environment. Here the authors analyse the T2SS pathway in three protist lineages and suggest that the early mitochondrion may have been capable of
Externí odkaz:
https://doaj.org/article/994e70e482df4d9db87d65239e08f13f
Autor:
Ana C. Reis, Boris A. Kolvenbach, Mohamed Chami, Luís Gales, Conceição Egas, Philippe F.-X. Corvini, Olga C. Nunes
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract Background Microbial communities recurrently establish metabolic associations resulting in increased fitness and ability to perform complex tasks, such as xenobiotic degradation. In a previous study, we have described a sulfonamide-degrading
Externí odkaz:
https://doaj.org/article/0dd810ea15bc46ebaab0ff72b99e21a2
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
2D crystals of the MloK1 potassium channel diffract to only 10 Å. Here the authors present a method, where they apply cryo-EM single-particle image processing to recorded 2D crystal images, which reveals conformational conformational variability of
Externí odkaz:
https://doaj.org/article/714e4f4cdcf04cc487fb9cd2715a0b91