Adrenocortical development: Lessons from mouse models

Autor: T. Dumontet, Pierre Val, Nathanaëlle Montanier, Antoine Martinez, Isabelle Sahut-Barnola, Anne Marie Lefrançois-Martinez, David T. Breault, Ingrid Plotton, Amandine Septier, Jean Christophe Pointud, Véronique Ducros, Mohamad Zubair, Florence Roucher-Boulez, Ken Ichirou Morohashi

Publikováno v: Annales d'Endocrinologie
Annales d'Endocrinologie, Elsevier Masson, 2018, 79 (3), pp.95-97. ⟨10.1016/j.ando.2018.03.014⟩
Annales d'Endocrinologie, 2018, 79 (3), pp.95-97. ⟨10.1016/j.ando.2018.03.014⟩

International audience; The adrenocortical gland undergoes structural and functional remodelling in the fetal and postnatal periods. After birth, the fetal zone of the gland undergoes rapid involution in favor of the definitive cortex, which reaches

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335657b17af848457e450b1a76c0b5ef
https://hal.archives-ouvertes.fr/hal-02366434

Differential gene dosage effects of Ad4BP/SF-1 on target tissue development

Autor: Mohamad Zubair, Satoru Ishihara, Yuko Fukui-Katoh, Fatchiyah, Ken Ichirou Morohashi, Yuichi Shima, Sanae Oka

Publikováno v: Biochemical and Biophysical Research Communications. 341:1036-1045

Ad4BP/SF-1 (NR5A1) was identified as a key regulator of the hypothalamus-pituitary-gonadal and -adrenal axes. Loss-of-function studies revealed that Ad4BP/SF-1 is essential for the development of these tissues and spleen. Here, we generated transgeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63e82b708cece83ce04be5dfe7ee266
https://doi.org/10.1016/j.bbrc.2006.01.058

Genetic labelling of specific axonal pathways in the mouse central nervous system

Autor: Eiji Watanabe, Masaharu Noda, Mohamad Zubair, Masahide Fukada

Publikováno v: European Journal of Neuroscience. 15:807-814

We report on transgenic mouse lines in which several sensory systems in the brain are specifically visualized genetically. We employed GAP-lacZ as an axon-targeted reporter protein that was constructed by fusing the membrane-anchoring domain of the G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3080f38dd70e3b9904a3042973bb5590
https://doi.org/10.1046/j.1460-9568.2002.01911.x

The paternal methylation imprint of the mouseH19locus is acquired in the gonocyte stage during foetal testis development

Autor: Takayuki Ueda, Kuniya Abe, Yoshihide Hayashizaki, Asuka Miura, Motoko Noguchi, Yoichi Matsuda, Misako Yuzuriha, Hiroyuki Sasaki, Yosuke Kawase, Mohamad Zubair, Katsutoshi Niwa, Hideo Shibata, Hirokazu Fujimoto, Tomohiro Kono

Publikováno v: Genes to Cells. 5:649-659

Background Germline-specific differential DNA methylation that persists through fertilization and embryonic development is thought to be the ‘imprint’ distinguishing the parental alleles of imprinted genes. If such methylation is to work as the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eee728b01053781ddc47ca44e37b5dd3
https://doi.org/10.1046/j.1365-2443.2000.00351.x

The fetal and adult adrenal cortex

Autor: Ken Ichirou Morohashi, Mohamad Zubair

Publikováno v: Molecular and cellular endocrinology. 336(1-2)

The orphan nuclear receptor AD4BP/SF-1 (adrenal-4-binding protein/steroidogenic factor-1 (NR5A1)) is essential for the proper development and function of reproductive and steroidogenic tissues. Although the expression of Ad4BP/Sf-1 is specific for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6c03bd71be844df93291985ae70305
https://pubmed.ncbi.nlm.nih.gov/21130838