Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mohamad Zubair"'
Publikováno v:
Biology of Reproduction. 79:1074-1083
The nuclear receptor steroidogenic factor 1 (SF-1 [officially designated NR5A1]) is essential for fetal gonadal development, but its roles in postnatal ovarian function are less well defined. Herein, we have extended our analyses of knockout (KO) mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d762de050ee62726ba15d01d4f7dca9
https://doi.org/10.1095/biolreprod.108.069435
https://doi.org/10.1095/biolreprod.108.069435
Autor:
Mohamad Zubair, Satoru Ishihara, Yuko Fukui-Katoh, Fatchiyah, Ken Ichirou Morohashi, Yuichi Shima, Sanae Oka
Publikováno v:
Biochemical and Biophysical Research Communications. 341:1036-1045
Ad4BP/SF-1 (NR5A1) was identified as a key regulator of the hypothalamus-pituitary-gonadal and -adrenal axes. Loss-of-function studies revealed that Ad4BP/SF-1 is essential for the development of these tissues and spleen. Here, we generated transgeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63e82b708cece83ce04be5dfe7ee266
https://doi.org/10.1016/j.bbrc.2006.01.058
https://doi.org/10.1016/j.bbrc.2006.01.058
Autor:
Hiroyuki Sasaki, Takashi Sado, Ken Tsutsui, Wahyu Purbowasito, Takaaki Yokomine, Chikako Suda, Mohamad Zubair
Publikováno v:
DNA Research. 11:391-407
Mammalian imprinted genes, which are expressed from only one of the parental alleles, have a tendency to form clusters and are regulated by long-range mechanisms. Nuclear matrix-attachment regions (MARs), the anchor points of loop domains, are involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd56c6dd7979f6fbcad4b35444d9c6ff
https://doi.org/10.1093/dnares/11.6.391
https://doi.org/10.1093/dnares/11.6.391
Publikováno v:
European Journal of Neuroscience. 15:807-814
We report on transgenic mouse lines in which several sensory systems in the brain are specifically visualized genetically. We employed GAP-lacZ as an axon-targeted reporter protein that was constructed by fusing the membrane-anchoring domain of the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3080f38dd70e3b9904a3042973bb5590
https://doi.org/10.1046/j.1460-9568.2002.01911.x
https://doi.org/10.1046/j.1460-9568.2002.01911.x
Autor:
Mohamad Zubair, Tomonobu Hasegawa, Richard J. Auchus, Tomohiro Ishii, Goro Sasaki, Toshikatsu Mitsui
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 28(7)
The steroidogenic acute regulatory protein (StAR) facilitates the delivery of cholesterol to the inner mitochondrial membrane, where the cholesterol side-chain cleavage enzyme catalyzes the initial step of steroid hormone biosynthesis. StAR was initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82546280b070bfe00b5760e3826089d
https://pubmed.ncbi.nlm.nih.gov/24850413
https://pubmed.ncbi.nlm.nih.gov/24850413
Autor:
Takayuki Ueda, Kuniya Abe, Yoshihide Hayashizaki, Asuka Miura, Motoko Noguchi, Yoichi Matsuda, Misako Yuzuriha, Hiroyuki Sasaki, Yosuke Kawase, Mohamad Zubair, Katsutoshi Niwa, Hideo Shibata, Hirokazu Fujimoto, Tomohiro Kono
Publikováno v:
Genes to Cells. 5:649-659
Background Germline-specific differential DNA methylation that persists through fertilization and embryonic development is thought to be the ‘imprint’ distinguishing the parental alleles of imprinted genes. If such methylation is to work as the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee728b01053781ddc47ca44e37b5dd3
https://doi.org/10.1046/j.1365-2443.2000.00351.x
https://doi.org/10.1046/j.1365-2443.2000.00351.x
Autor:
Hiroyuki Sasaki, B. Bailleul, Mohamad Zubair, Robert Feil, Tom Moore, Wolf Reik, Miguel Constancia
Publikováno v:
Proceedings of the National Academy of Sciences. 94:12509-12514
The mouse insulin-like growth factor 2 ( Igf2 ) locus is a complex genomic region that produces multiple transcripts from alternative promoters. Expression at this locus is regulated by parental imprinting. However, despite the existence of putative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33082282366c41091ca007a78204a44
https://doi.org/10.1073/pnas.94.23.12509
https://doi.org/10.1073/pnas.94.23.12509
Autor:
Ken Ichirou Morohashi, Mohamad Zubair
Publikováno v:
Molecular and cellular endocrinology. 336(1-2)
The orphan nuclear receptor AD4BP/SF-1 (adrenal-4-binding protein/steroidogenic factor-1 (NR5A1)) is essential for the proper development and function of reproductive and steroidogenic tissues. Although the expression of Ad4BP/Sf-1 is specific for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6c03bd71be844df93291985ae70305
https://pubmed.ncbi.nlm.nih.gov/21130838
https://pubmed.ncbi.nlm.nih.gov/21130838
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 23(10)
Deficiency of adrenal 4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1; NR5A1) impairs adrenal development in a dose-dependent manner, whereas overexpression of Ad4BP/SF-1 is associated with adrenocortical tumorigenesis. Despite its essential rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb3445faa578a436790a217f65574a1
https://pubmed.ncbi.nlm.nih.gov/19628584
https://pubmed.ncbi.nlm.nih.gov/19628584
Publikováno v:
IFMBE Proceedings ISBN: 9783540928409
The purpose of this study is addressed the function of Ad4BP/SF1 in developing spleen of Ad4BP/SF-1 KO mouse. I have modified the BAC-Ad4BP endogenous by homologous recombinant with modification cassette-containing tetracycline transactivator system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9118cbce4b548a76b64bb11f2ce9948a
https://doi.org/10.1007/978-3-540-92841-6_477
https://doi.org/10.1007/978-3-540-92841-6_477
