Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mohamad Wessam, Alnouri"'
Autor:
Nils Helge Schebb, Hartmut Kühn, Astrid S. Kahnt, Katharina M. Rund, Valerie B. O’Donnell, Nicolas Flamand, Marc Peters-Golden, Per-Johan Jakobsson, Karsten H. Weylandt, Nadine Rohwer, Robert C. Murphy, Gerd Geisslinger, Garret A. FitzGerald, Julien Hanson, Claes Dahlgren, Mohamad Wessam Alnouri, Stefan Offermanns, Dieter Steinhilber
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 1
Externí odkaz:
https://doaj.org/article/4d550b6401b044cfacb01d9180ee3c13
Autor:
Sisignano, Saskia Wedel, Lisa Hahnefeld, Mohamad Wessam Alnouri, Stefan Offermanns, Felix Hausch, Gerd Geisslinger, Marco
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14274
Neuropathic pain is a pathological pain state with a broad symptom scope that affects patients after nerve injuries, but it can also arise after infections or exposure to toxic substances. Current treatment possibilities are still limited because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::ed6be2adcd64842956203f0203562962
Autor:
Saskia, Wedel, Lisa, Hahnefeld, Mohamad Wessam, Alnouri, Stefan, Offermanns, Felix, Hausch, Gerd, Geisslinger, Marco, Sisignano
Publikováno v:
International journal of molecular sciences. 23(22)
Neuropathic pain is a pathological pain state with a broad symptom scope that affects patients after nerve injuries, but it can also arise after infections or exposure to toxic substances. Current treatment possibilities are still limited because of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dda1b68ac9e720a1eedfa7f278c3c70
https://pubmed.ncbi.nlm.nih.gov/36430751
https://pubmed.ncbi.nlm.nih.gov/36430751
Autor:
Alan Le Mercier, Weijia Yu, Boris Strilic, Remy Bonnavion, Yannick Jäger, Xinyi Chen, Hyun-Woo Jeong, Mohamad Wessam Alnouri, Michael A. Rieger, Yang Zhang, Stefan Offermanns, Sophie Ramas, Kishor K. Sivaraj, Tjeerd Sijmonsma, Haaglim Cho, Timm Schroeder, Ralf H. Adams, Kenneth Anthony Roquid
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 118 (17)
Proceedings of the National Academy of Sciences of the United States of America, 118 (17)
G protein–coupled receptor 182 (GPR182) has been shown to be expressed in endothelial cells; however, its ligand and physiological role has remained elusive. We found GPR182 to be expressed in microvascular and lymphatic endothelial cells of most o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088d86aaf670dfd5c694c17127f3a38f
http://europepmc.org/articles/PMC8092405
http://europepmc.org/articles/PMC8092405
Autor:
Aliaa, Abdelrahman, Swapnil G, Yerande, Vigneshwaran, Namasivayam, Tim A, Klapschinski, Mohamad Wessam, Alnouri, Ali, El-Tayeb, Christa E, Müller
Publikováno v:
European journal of medicinal chemistry. 186
Adenosine acts as a powerful signaling molecule via four distinct G protein-coupled receptors, designated A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb0ae0a1e289bd5dba290ea7fde1f636
https://pubmed.ncbi.nlm.nih.gov/31780082
https://pubmed.ncbi.nlm.nih.gov/31780082
Autor:
Ali El-Tayeb, Christa E. Müller, Mohamad Wessam Alnouri, Swapnil G. Yerande, Aliaa Abdelrahman, Tim A. Klapschinski, Vigneshwaran Namasivayam
Publikováno v:
European Journal of Medicinal Chemistry. 186:111879
Adenosine acts as a powerful signaling molecule via four distinct G protein-coupled receptors, designated A1, A2A, A2B and A3 adenosine receptors (ARs). A2A and A2B ARs are Gs-coupled, while A1 and A3 ARs inhibit cAMP production via Gi proteins. Anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8961c47e894c6a83567a61b0c76aea8
https://doi.org/10.1016/j.ejmech.2019.111879
https://doi.org/10.1016/j.ejmech.2019.111879
Autor:
Sonja Hinz, Stephan Jepards, Christa E. Müller, Anke C. Schiedel, Mohamad Wessam Alnouri, Alessandro Casari
Adenosine receptors (ARs) have emerged as new drug targets. The majority of data on affinity/potency and selectivity of AR ligands described in the literature has been obtained for the human species. However, preclinical studies are mostly performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8a1cbf2f3d928f8b830ab5fa3bcd0b
https://europepmc.org/articles/PMC4529847/
https://europepmc.org/articles/PMC4529847/
Autor:
Jamshed Iqbal, Jürgen Gäb, Minka Paskaleva, Mohamad Wessam Alnouri, Michael Gütschow, Christa E. Müller, Silvia Scolari, Miriam Schlenk
Publikováno v:
Journal of medicinal chemistry. 55(7)
2-(Acyl)amino-4H-3,1-benzothiazin-4-ones and related thienothiazinones were identified as structurally novel antagonists at adenosine receptors (ARs). 6-Methyl-2-benzoylamino-4H-3,1-benzothiazin-4-one (10d) was found to be a balanced AR antagonist wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdf1af168c43a67d454e5451c98a891
https://pubmed.ncbi.nlm.nih.gov/22409573
https://pubmed.ncbi.nlm.nih.gov/22409573